Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 11491875 . A C CCDS12260.1:NM_000121.3:c.596cTg>cGg_NP_000112.1:p.199L>R Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2jix 2 P19235 100.0 5e-161 X-RAY
 2007-07-10 LEU B:175 B:175 110.0 0.647 -73.9 153.1 NA NA NA
LEU C:175 C:175 116.0 0.682 -56.0 144.4 116.0 0.682 0.0
LEU E:175 E:175 119.0 0.7 -47.7 143.1 NA NA NA
1cn4 1 P19235 98.23 9e-159 X-RAY
 1999-08-11 LEU A:178 A:175 109.0 0.641 -69.1 136.3 109.0 0.641 0.0 HOH
 8.723
 C
 O
LEU B:178 B:175 122.0 0.718 E -73.4 163.3 122.0 0.718 0.0
1eer 2 P19235 98.22 3e-156 X-RAY
 1999-10-01 LEU B:176 B:175 119.0 0.7 -45.7 143.9 118.0 0.694 0.006 A:P01588:0.006
 HOH
 3.618
 CG
 O
LEU C:176 C:175 111.0 0.653 -60.6 145.2 111.0 0.653 0.0 HOH
 3.313
 N
 O
4y5v 3 P19235 99.08 7e-155 X-RAY
 2015-04-29 LEU C:173 C:175 105.0 0.618 -66.7 156.2 105.0 0.618 0.0 HOH
 4.571
 N
 O
LEU F:173 F:175 108.0 0.635 -66.2 155.8 108.0 0.635 0.0 HOH
 5.769
 N
 O
LEU I:173 I:175 107.0 0.629 -66.1 156.9 NA NA NA
4y5x 3 P19235 99.08 7e-155 X-RAY
 2015-03-18 LEU C:173 C:175 119.0 0.7 -63.0 159.6 102.0 0.6 0.1 L:P19235:0.1
LEU F:173 F:175 110.0 0.647 -61.4 160.2 NA NA NA
LEU I:173 I:175 138.0 0.812 -63.2 158.6 NA NA NA
LEU L:173 L:175 117.0 0.688 -64.1 158.6 102.0 0.6 0.088 C:P19235:0.088
6moe 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU C:173 C:175 116.0 0.682 -62.4 158.0 NA NA NA
LEU D:173 D:175 106.0 0.624 -63.3 158.4 106.0 0.624 0.0 HOH
 4.831
 N
 O
6mof 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU B:173 B:175 111.0 0.653 -67.9 172.8 111.0 0.653 0.0
6moh 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU C:173 C:175 146.0 0.859 -60.7 144.4 90.0 0.529 0.33 D:P19235:0.329
LEU D:173 D:175 141.0 0.829 -60.6 145.9 51.0 0.3 0.529 C:P19235:0.529
6moi 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU B:173 B:175 86.0 0.506 -65.6 173.8 19.0 0.112 0.394 B:P19235:0.394
 HOH
 3.575
 CD2
 O
6moj 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU B:173 B:175 111.0 0.653 -54.7 158.3 111.0 0.653 0.0 TAR
HOH
 8.390
9.313
 N
N
 O2
O
6mok 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU B:173 B:175 91.0 0.535 -68.4 172.1 91.0 0.535 0.0
6mol 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 LEU B:173 B:175 108.0 0.635 -67.7 150.8 108.0 0.635 0.0
LEU C:173 C:175 100.0 0.588 -65.3 149.5 100.0 0.588 0.0
1eba 1 P19235 100.0 2e-153 X-RAY
 1998-11-11 LEU A:166 A:175 91.0 0.535 -48.6 132.5 45.0 0.265 0.27 B:P19235:0.271
LEU B:166 B:175 100.0 0.588 -65.4 165.3 56.0 0.329 0.259 A:P19235:0.259
4y5y 3 P19235 99.07 3e-152 X-RAY
 2015-03-18 LEU C:173 C:175 50.0 NA -115.7 172.5 50.0 NA NA
LEU F:173 F:175 96.0 0.565 -115.1 170.6 96.0 0.565 0.0
1ern 1 P19235 100.0 8e-152 X-RAY
 2000-01-07 LEU A:166 A:175 91.0 0.535 -109.0 173.7 91.0 0.535 0.0 HOH
 8.017
 C
 O
LEU B:166 B:175 107.0 0.629 -55.1 -149.6 107.0 0.629 0.0 HOH
 6.879
 O
 O
1ebp 1 P19235 100.0 1e-150 X-RAY
 1997-07-29 LEU A:166 A:175 100.0 0.588 -80.9 155.3 63.0 0.371 0.217 B:P19235:0.218
LEU B:166 B:175 85.0 0.5 -71.6 156.3 37.0 0.218 0.282 A:P19235:0.282

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19235-f1 1 P19235 100.0 0.0 LEU A:199 A:199 137.0 0.806 -57.0 155.0