Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 11492666 | . | G | A | CCDS12260.1:NM_000121.3:c.367Cgc>Tgc_NP_000112.1:p.123R>C | Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2jix | 2 | P19235 | 100.0 | 5e-161 |
X-RAY |
2007-07-10 | ARG | B:99 | B:99 | 105.0 | 0.467 | E | -136.2 | 116.6 | NA | NA | NA | ||||||
ARG | C:99 | C:99 | 107.0 | 0.476 | E | -122.5 | 123.7 | 3.0 | 0.013 | 0.463 |
A:None:0.071 F:None:0.444 |
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ARG | E:99 | E:99 | 117.0 | 0.52 | E | -139.1 | 107.6 | NA | NA | NA | |||||||||||||
1cn4 | 1 | P19235 | 98.23 | 9e-159 |
X-RAY |
1999-08-11 | ARG | A:102 | A:99 | 94.0 | 0.418 | E | -129.5 | 117.6 | 94.0 | 0.418 | 0.0 |
HOH |
6.955 |
O |
O |
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ARG | B:102 | B:99 | 106.0 | 0.471 | E | -135.8 | 118.4 | 106.0 | 0.471 | 0.0 | |||||||||||||
1eer | 2 | P19235 | 98.22 | 3e-156 |
X-RAY |
1999-10-01 | ARG | B:100 | B:99 | 99.0 | 0.44 | E | -143.6 | 120.4 | 99.0 | 0.44 | 0.0 |
HOH |
2.674 |
NH2 |
O |
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ARG | C:100 | C:99 | 101.0 | 0.449 | E | -151.2 | 130.6 | 101.0 | 0.449 | 0.0 |
HOH |
2.871 |
O |
O |
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4y5v | 3 | P19235 | 99.08 | 7e-155 |
X-RAY |
2015-04-29 | ARG | C:97 | C:99 | 79.0 | 0.351 | E | -145.1 | 116.9 | 79.0 | 0.351 | 0.0 |
HOH |
8.322 |
CA |
O |
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ARG | F:97 | F:99 | 82.0 | 0.364 | E | -144.3 | 115.7 | 82.0 | 0.364 | 0.0 |
HOH |
6.116 |
NH2 |
O |
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ARG | I:97 | I:99 | 97.0 | 0.431 | E | -142.6 | 116.3 | NA | NA | NA | |||||||||||||
4y5x | 3 | P19235 | 99.08 | 7e-155 |
X-RAY |
2015-03-18 | ARG | C:97 | C:99 | 88.0 | 0.391 | E | -155.6 | 119.0 | 88.0 | 0.391 | 0.0 |
PEG |
3.613 |
NH2 |
O4 |
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ARG | F:97 | F:99 | 86.0 | 0.382 | E | -154.3 | 117.7 | NA | NA | NA | |||||||||||||
ARG | I:97 | I:99 | 91.0 | 0.404 | E | -153.9 | 117.5 | NA | NA | NA | |||||||||||||
ARG | L:97 | L:99 | 84.0 | 0.373 | E | -153.4 | 117.6 | 84.0 | 0.373 | 0.0 |
PEG |
7.363 |
NH1 |
O1 |
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6moe | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | C:97 | C:99 | 101.0 | 0.449 | E | -134.7 | 135.5 | NA | NA | NA | ||||||
ARG | D:97 | D:99 | 103.0 | 0.458 | E | -134.2 | 135.6 | 5.0 | 0.022 | 0.436 |
A:None:0.436 |
EDO PO4 HOH |
7.011 9.907 2.857 |
CD N NH2 |
C1 O2 O |
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6mof | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | B:97 | B:99 | 96.0 | 0.427 | E | -143.6 | 118.8 | 4.0 | 0.018 | 0.409 |
A:None:0.409 |
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6moh | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | C:97 | C:99 | 106.0 | 0.471 | E | -146.0 | 133.8 | 6.0 | 0.027 | 0.444 |
B:None:0.444 |
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ARG | D:97 | D:99 | 93.0 | 0.413 | E | -147.8 | 135.4 | 6.0 | 0.027 | 0.386 |
A:None:0.387 |
PO4 |
9.809 |
NH1 |
O4 |
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6moi | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | B:97 | B:99 | 96.0 | 0.427 | E | -142.3 | 124.1 | 4.0 | 0.018 | 0.409 |
A:None:0.409 |
EDO PEG EDO HOH |
6.304 7.093 9.708 2.990 |
NH1 CD N O |
O2 C1 C2 O |
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6moj | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | B:97 | B:99 | 101.0 | 0.449 | E | -140.9 | 128.0 | 4.0 | 0.018 | 0.431 |
A:None:0.431 |
HOH |
2.697 |
NH2 |
O |
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6mok | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | B:97 | B:99 | 87.0 | 0.387 | E | -143.0 | 128.6 | 2.0 | 0.009 | 0.378 |
A:None:0.378 |
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6mol | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | ARG | B:97 | B:99 | 108.0 | 0.48 | E | -146.7 | 121.6 | 7.0 | 0.031 | 0.449 |
A:None:0.449 |
GOL |
5.434 |
NH2 |
O1 |
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ARG | C:97 | C:99 | 109.0 | 0.484 | E | -146.6 | 121.5 | 4.0 | 0.018 | 0.466 |
A:None:0.467 |
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1eba | 1 | P19235 | 100.0 | 2e-153 |
X-RAY |
1998-11-11 | ARG | A:90 | A:99 | 72.0 | 0.32 | E | -143.2 | 138.9 | 72.0 | 0.32 | 0.0 | ||||||
ARG | B:90 | B:99 | 107.0 | 0.476 | E | -127.1 | 122.8 | 107.0 | 0.476 | 0.0 | |||||||||||||
4y5y | 3 | P19235 | 99.07 | 3e-152 |
X-RAY |
2015-03-18 | ARG | C:97 | C:99 | 81.0 | 0.36 | E | -145.3 | 127.0 | 81.0 | 0.36 | 0.0 | ||||||
ARG | F:97 | F:99 | 81.0 | 0.36 | E | -145.6 | 127.5 | 81.0 | 0.36 | 0.0 |
HOH |
7.909 |
NH2 |
O |
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1ern | 1 | P19235 | 100.0 | 8e-152 |
X-RAY |
2000-01-07 | ARG | A:90 | A:99 | 73.0 | 0.324 | E | -146.7 | 114.7 | 73.0 | 0.324 | 0.0 |
HOH |
2.760 |
O |
O |
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ARG | B:90 | B:99 | 90.0 | 0.4 | E | -169.7 | 118.9 | 90.0 | 0.4 | 0.0 |
HOH |
2.969 |
O |
O |
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1ebp | 1 | P19235 | 100.0 | 1e-150 |
X-RAY |
1997-07-29 | ARG | A:90 | A:99 | 75.0 | 0.333 | E | -156.0 | 126.4 | 75.0 | 0.333 | 0.0 | ||||||
ARG | B:90 | B:99 | 108.0 | 0.48 | E | -141.9 | 118.4 | 108.0 | 0.48 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p19235-f1 | 1 | P19235 | 100.0 | 0.0 | ARG | A:123 | A:123 | 105.0 | 0.467 | E | -134.5 | 128.3 |