Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 36634002 . C A CCDS12489.1:NM_001003962.1:c.428aCa>aAa_NP_001003962.1:p.143T>K Homo sapiens calpain, small subunit 1 (CAPNS1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1kfu 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 THR B:59 S:843 7.0 0.05 H -59.2 -54.0 7.0 0.05 0.0 HOH
 3.072
 N
 O
1kfx 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 THR B:59 S:843 7.0 0.05 H -54.2 -47.7 7.0 0.05 0.0 HOH
 3.085
 OG1
 O
4phj 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 THR A:48 A:143 39.0 0.279 H -61.8 -40.9 9.0 0.064 0.215 B:P04632:0.214
 CA
HOH
 7.103
2.821
 OG1
O
 CA
O
THR B:48 B:143 40.0 0.286 H -59.9 -42.0 8.0 0.057 0.229 A:P04632:0.229
 CA
HOH
 7.009
2.526
 OG1
OG1
 CA
O
4phk 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 THR A:48 A:143 36.0 0.257 H -62.8 -40.0 10.0 0.071 0.186 B:P04632:0.186
 CA
CA
HOH
 7.264
9.981
2.829
 OG1
N
O
 CA
CA
O
THR B:48 B:143 39.0 0.279 H -56.5 -40.1 11.0 0.079 0.2 A:P04632:0.2
 CA
HOH
 7.033
2.859
 OG1
N
 CA
O
4phm 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 THR A:48 A:143 42.0 0.3 H -63.1 -42.1 14.0 0.1 0.2 B:P04632:0.2
 CA
HOH
 7.319
2.782
 OG1
N
 CA
O
THR B:48 B:143 47.0 0.336 H -55.1 -39.4 15.0 0.107 0.229 A:P04632:0.229
 CA
HOH
 7.093
2.819
 OG1
N
 CA
O
4wq2 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 THR A:48 A:143 39.0 0.279 H -58.4 -42.2 9.0 0.064 0.215 B:P04632:0.214
 CA
EDO
HOH
 6.980
8.174
2.944
 OG1
O
N
 CA
C1
O
THR B:48 B:143 42.0 0.3 H -61.9 -41.5 12.0 0.086 0.214 A:P04632:0.214
 CA
HOH
 7.117
3.186
 OG1
OG1
 CA
O
4wq3 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 THR A:48 A:143 36.0 0.257 H -66.9 -39.0 8.0 0.057 0.2 B:P04632:0.2
 CA
HOH
 7.230
2.845
 OG1
O
 CA
O
THR B:48 B:143 40.0 0.286 H -55.6 -44.7 7.0 0.05 0.236 A:P04632:0.236
 CA
HOH
 6.944
2.910
 OG1
O
 CA
O
5d69 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 THR A:48 A:143 38.0 0.271 H -65.0 -39.0 10.0 0.071 0.2 B:P04632:0.2
 CA
HOH
 7.219
3.093
 OG1
OG1
 CA
O
THR B:48 B:143 40.0 0.286 H -61.3 -40.5 11.0 0.079 0.207 A:P04632:0.207
 CA
HOH
 7.034
3.103
 OG1
OG1
 CA
O
1df0 2 Q64537 92.35 6e-129 X-RAY
 2000-06-21 THR B:59 B:59 8.0 0.057 H -64.0 -42.6 5.0 0.036 0.021 A:Q07009:0.021
 HOH
 6.500
 OG1
 O
1u5i 2 Q64537 92.35 6e-129 X-RAY
 2005-01-18 THR B:59 B:59 5.0 0.036 H -51.0 -38.4 1.0 0.007 0.029 A:Q07009:0.029
 HOH
 3.043
 OG1
 O
3bow 2 Q64537 92.35 6e-129 X-RAY
 2008-11-25 THR B:59 B:145 23.0 0.164 H -65.8 -43.0 23.0 0.164 0.0 CA
CA
HOH
 8.371
7.020
4.582
 N
OG1
OG1
 CA
CA
O
3df0 2 Q64537 92.35 6e-129 X-RAY
 2008-11-11 THR B:59 B:145 41.0 0.293 H -75.0 -34.0 24.0 0.171 0.122 A:Q07009:0.121
 CA
CA
 9.305
7.743
 N
CG2
 CA
CA
1dvi 1 Q64537 91.8 7e-128 X-RAY
 1998-05-27 THR A:59 A:145 38.0 0.271 H -68.2 -37.7 8.0 0.057 0.214 B:Q64537:0.214
 CA
CA
HOH
 6.695
9.898
2.952
 OG1
N
OG1
 CA
CA
O
THR B:59 B:145 39.0 0.279 H -70.2 -39.9 9.0 0.064 0.215 A:Q64537:0.214
 CA
CA
HOH
 9.663
6.829
2.906
 N
OG1
OG1
 CA
CA
O
1alv 1 P04574 97.11 8e-126 X-RAY
 1998-06-03 THR A:48 A:141 39.0 0.279 H -65.1 -41.8 10.0 0.071 0.208 B:P04574:0.207
 CA
CA
HOH
 6.950
9.617
2.288
 OG1
H
OG1
 CA
CA
H1
THR B:48 B:141 39.0 0.279 H -62.0 -41.4 9.0 0.064 0.215 A:P04574:0.214
 CA
CA
HOH
 9.782
6.858
1.306
 H
OG1
H
 CA
CA
H2
1alw 1 P04574 97.11 8e-126 X-RAY
 1998-06-10 THR A:48 A:141 28.0 0.2 H -68.9 -40.0 8.0 0.057 0.143 B:P04574:0.143
 CA
CA
HOH
 7.490
9.838
2.769
 CG2
N
CG2
 CA
CA
O
THR B:48 B:141 36.0 0.257 H -66.0 -38.6 7.0 0.05 0.207 A:P04574:0.207
 CA
HOH
 6.938
2.923
 OG1
OG1
 CA
O
1nx0 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 THR A:48 A:141 36.0 0.257 H -61.3 -37.8 12.0 0.086 0.171 B:P04574:0.171
 HOH
 4.689
 CG2
 O
THR B:48 B:441 33.0 0.236 H -63.2 -44.4 13.0 0.093 0.143 A:P04574:0.143
 HOH
 2.657
 OG1
 O
1nx1 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 THR A:48 A:141 41.0 0.293 H -62.6 -38.1 11.0 0.079 0.214 B:P04574:0.214
 CA
HOH
 7.239
2.606
 OG1
OG1
 CA
O
THR B:48 B:441 39.0 0.279 H -62.7 -37.6 10.0 0.071 0.208 A:P04574:0.207
 CA
HOH
 7.535
2.976
 OG1
N
 CA
O
1nx2 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 THR A:48 A:141 39.0 0.279 H -64.2 -40.7 10.0 0.071 0.208 A:P04574:0.207
 CA
CA
HOH
 6.843
9.926
2.841
 OG1
N
OG1
 CA
CA
O
1nx3 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 THR A:48 A:141 37.0 0.264 H -61.1 -40.6 6.0 0.043 0.221 A:P04574:0.221
 CA
CA
HOH
 6.734
9.918
2.696
 OG1
N
OG1
 CA
CA
O
4phn 1 P04574 97.11 8e-126 X-RAY
 2014-08-13 THR A:48 A:141 38.0 0.271 H -55.1 -43.3 8.0 0.057 0.214 B:P04574:0.214
 CA
CA
HOH
 7.129
9.855
2.763
 OG1
N
OG1
 CA
CA
O
THR B:48 B:141 34.0 0.243 H -65.1 -46.5 12.0 0.086 0.157 A:P04574:0.157
 CA
CA
HOH
 9.844
6.780
2.950
 N
OG1
O
 CA
CA
O
6qlb 1 P04632 92.49 1e-121 X-RAY
 2020-02-05 THR A:48 A:48 38.0 0.271 H -61.8 -42.9 11.0 0.079 0.192 B:P04632:0.193
 CA
CA
HOH
 7.048
9.870
2.984
 OG1
N
OG1
 CA
CA
O
THR B:48 B:48 38.0 0.271 H -60.6 -44.3 12.0 0.086 0.185 A:P04632:0.186
 CA
CA
HOH
 9.780
7.240
3.182
 N
OG1
OG1
 CA
CA
O
THR C:48 C:48 38.0 0.271 H -60.7 -45.1 13.0 0.093 0.178 D:P04632:0.179
 CA
CA
HOH
 6.999
9.850
4.796
 OG1
N
O
 CA
CA
O
THR D:48 D:48 37.0 0.264 H -59.3 -44.8 10.0 0.071 0.193 C:P04632:0.193
 CA
CA
HOH
 9.729
7.146
2.932
 N
OG1
O
 CA
CA
O
1aj5 1 Q64537 91.91 2e-120 X-RAY
 1998-05-20 THR A:48 A:145 31.0 0.221 H -58.3 -42.0 31.0 0.221 0.0 HOH
 3.661
 CA
 O
THR B:48 B:145 10.0 0.071 H -61.7 -40.6 NA NA NA
1qxp 1 Q07009,P97571,505658 91.76 2e-117 X-RAY
 2004-02-03 THR A:775 A:768 34.0 0.243 H -37.9 -69.0 34.0 0.243 0.0 HOH
 4.892
 CA
 O
THR B:775 B:768 35.0 0.25 H -43.1 -24.3 NA NA NA
1np8 1 Q64537 91.82 2e-109 X-RAY
 2003-11-18 THR A:55 A:59 26.0 0.186 H -66.8 -38.0 26.0 0.186 0.0 CD
HOH
 7.922
3.120
 CG2
N
 CD
O
THR B:55 B:559 34.0 0.243 H -67.7 -35.4 34.0 0.243 0.0 CD
CD
HOH
 9.252
8.248
3.187
 N
CG2
N
 CD
CD
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04632-f1 1 P04632 100.0 0.0 THR A:143 A:143 33.0 0.236 H -59.0 -47.3