Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 36636745 . A C CCDS12489.1:NM_001003962.1:c.494aAg>aCg_NP_001003962.1:p.165K>T Homo sapiens calpain, small subunit 1 (CAPNS1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1kfu 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 LYS B:81 S:865 49.0 0.245 H -63.7 -31.6 49.0 0.245 0.0 HOH
 4.225
 O
 O
1kfx 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 LYS B:81 S:865 57.0 0.285 H -41.7 -65.5 57.0 0.285 0.0
4phj 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 LYS A:70 A:165 81.0 0.405 H -57.1 -45.1 81.0 0.405 0.0 HOH
 3.113
 CE
 O
LYS B:70 B:165 78.0 0.39 H -56.1 -46.8 78.0 0.39 0.0 HOH
 3.384
 NZ
 O
4phk 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 LYS A:70 A:165 62.0 0.31 H -59.5 -43.4 62.0 0.31 0.0 HOH
 3.467
 CE
 O
LYS B:70 B:165 69.0 0.345 H -61.2 -42.1 69.0 0.345 0.0 HOH
 3.028
 CE
 O
4phm 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 LYS A:70 A:165 57.0 0.285 H -59.7 -45.6 57.0 0.285 0.0 2UD
HOH
 9.267
4.676
 O
O
 CAC
O
LYS B:70 B:165 72.0 0.36 H -57.8 -47.3 72.0 0.36 0.0 2UD
HOH
 9.537
3.549
 O
O
 CAC
O
4wq2 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 LYS A:70 A:165 65.0 0.325 H -59.6 -41.6 65.0 0.325 0.0 EDO
HOH
 4.406
2.795
 CD
NZ
 O2
O
LYS B:70 B:165 73.0 0.365 H -60.4 -44.9 73.0 0.365 0.0 3SU
HOH
 9.747
3.651
 O
CE
 NAA
O
4wq3 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 LYS A:70 A:165 64.0 0.32 H -60.9 -39.4 64.0 0.32 0.0 3SU
3SU
HOH
 8.469
8.269
3.093
 CA
O
NZ
 BR
OAN
O
LYS B:70 B:165 79.0 0.395 H -57.0 -47.1 79.0 0.395 0.0 3SU
3SU
HOH
 8.635
9.583
3.779
 CG
O
CE
 OAN
NAA
O
5d69 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 LYS A:70 A:165 71.0 0.355 H -60.3 -45.8 71.0 0.355 0.0 57T
HOH
 8.609
3.842
 N
O
 IAT
O
LYS B:70 B:165 72.0 0.36 H -57.8 -41.7 72.0 0.36 0.0 57T
HOH
 8.461
3.851
 N
CE
 IAZ
O
1df0 2 Q64537 92.35 6e-129 X-RAY
 2000-06-21 LYS B:81 B:81 30.0 0.15 H -67.2 -45.4 30.0 0.15 0.0 HOH
 3.425
 NZ
 O
1u5i 2 Q64537 92.35 6e-129 X-RAY
 2005-01-18 LYS B:81 B:81 21.0 0.105 H -70.6 -49.0 21.0 0.105 0.0 HOH
 2.105
 NZ
 O
3bow 2 Q64537 92.35 6e-129 X-RAY
 2008-11-25 LYS B:81 B:167 64.0 0.32 H -59.3 -46.6 64.0 0.32 0.0 HOH
 9.220
 CE
 O
3df0 2 Q64537 92.35 6e-129 X-RAY
 2008-11-11 LYS B:81 B:167 52.0 0.26 H -48.2 -52.6 52.0 0.26 0.0 CA
 9.623
 N
 CA
1dvi 1 Q64537 91.8 7e-128 X-RAY
 1998-05-27 LYS A:81 A:167 50.0 0.25 H -66.0 -48.1 50.0 0.25 0.0 HOH
 2.763
 NZ
 O
LYS B:81 B:167 62.0 0.31 H -63.5 -47.7 62.0 0.31 0.0 HOH
 3.128
 CD
 O
1alv 1 P04574 97.11 8e-126 X-RAY
 1998-06-03 LYS A:70 A:163 73.0 0.365 H -61.7 -48.6 73.0 0.365 0.0 CA
HOH
 9.588
3.432
 H
CB
 CA
H1
LYS B:70 B:163 70.0 0.35 H -59.9 -41.7 70.0 0.35 0.0 CA
HOH
 9.663
2.817
 H
HZ2
 CA
H1
1alw 1 P04574 97.11 8e-126 X-RAY
 1998-06-10 LYS A:70 A:163 53.0 0.265 H -69.6 -40.8 53.0 0.265 0.0 HOH
 7.419
 C
 O
LYS B:70 B:163 64.0 0.32 H -63.1 -36.5 64.0 0.32 0.0 HOH
 4.141
 CB
 O
1nx0 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 LYS A:70 A:163 51.0 0.255 H -60.1 -45.3 51.0 0.255 0.0 HOH
 4.021
 CE
 O
LYS B:70 B:463 45.0 0.225 H -59.0 -43.1 45.0 0.225 0.0 HOH
 3.802
 CE
 O
1nx1 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 LYS A:70 A:163 32.0 0.16 H -64.9 -39.8 32.0 0.16 0.0 HOH
 3.165
 NZ
 O
LYS B:70 B:463 38.0 0.19 H -66.5 -44.4 38.0 0.19 0.0 HOH
 6.429
 CE
 O
1nx2 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 LYS A:70 A:163 52.0 0.26 H -61.0 -46.0 52.0 0.26 0.0 HOH
 3.049
 NZ
 O
1nx3 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 LYS A:70 A:163 59.0 0.295 H -67.5 -46.2 59.0 0.295 0.0 ISA
HOH
 9.997
3.400
 O
CD
 S3
O
4phn 1 P04574 97.11 8e-126 X-RAY
 2014-08-13 LYS A:70 A:163 73.0 0.365 H -50.6 -53.8 73.0 0.365 0.0 HOH
 3.670
 CE
 O
LYS B:70 B:163 75.0 0.375 H -56.6 -46.4 75.0 0.375 0.0 HOH
 2.605
 NZ
 O
6qlb 1 P04632 92.49 1e-121 X-RAY
 2020-02-05 LYS A:70 A:70 56.0 0.28 H -55.3 -49.0 56.0 0.28 0.0 HOH
 7.565
 O
 O
LYS B:70 B:70 64.0 0.32 H -55.6 -47.5 64.0 0.32 0.0 HOH
 7.087
 O
 O
LYS C:70 C:70 62.0 0.31 H -56.0 -47.0 62.0 0.31 0.0 P4G
HOH
 7.249
3.996
 C
CB
 C4
O
LYS D:70 D:70 65.0 0.325 H -55.0 -48.7 65.0 0.325 0.0 P4G
HOH
 7.499
9.743
 C
CD
 O3
O
1aj5 1 Q64537 91.91 2e-120 X-RAY
 1998-05-20 LYS A:70 A:167 36.0 0.18 H -59.9 -44.3 36.0 0.18 0.0 HOH
 3.840
 NZ
 O
LYS B:70 B:167 43.0 0.215 H -63.3 -39.3 NA NA NA
1qxp 1 Q07009,P97571,505658 91.76 2e-117 X-RAY
 2004-02-03 LYS A:797 A:790 41.0 NA H -33.9 -41.5 41.0 NA NA HOH
 4.422
 CB
 O
LYS B:797 B:790 122.0 0.61 H -42.5 -71.6 NA NA NA
1np8 1 Q64537 91.82 2e-109 X-RAY
 2003-11-18 LYS A:77 A:81 77.0 0.385 H -58.7 -47.4 77.0 0.385 0.0 HOH
 3.699
 CB
 O
LYS B:77 B:581 62.0 0.31 H -60.2 -45.0 62.0 0.31 0.0 HOH
 4.052
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04632-f1 1 P04632 100.0 0.0 LYS A:165 A:165 62.0 0.31 H -59.6 -47.4