Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 36636896 . G A CCDS12489.1:NM_001003962.1:c.544Gac>Aac_NP_001003962.1:p.182D>N Homo sapiens calpain, small subunit 1 (CAPNS1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1kfu 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 ASP B:98 S:882 2.0 0.013 -137.8 73.7 2.0 0.013 0.0 HOH
 3.920
 N
 O
1kfx 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 ASP B:98 S:882 9.0 0.06 -105.1 98.2 9.0 0.06 0.0 HOH
 6.873
 O
 O
4phj 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:87 A:182 5.0 0.033 -84.7 71.1 5.0 0.033 0.0 CA
HOH
 2.292
4.620
 OD1
OD1
 CA
O
ASP B:87 B:182 4.0 0.027 -85.8 69.5 4.0 0.027 0.0 CA
HOH
 2.265
2.812
 OD1
OD2
 CA
O
4phk 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:87 A:182 6.0 0.04 -79.4 48.0 6.0 0.04 0.0 CA
HOH
 2.246
4.412
 OD1
OD1
 CA
O
ASP B:87 B:182 3.0 0.02 -79.7 70.2 3.0 0.02 0.0 CA
HOH
 2.235
2.998
 OD1
OD2
 CA
O
4phm 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:87 A:182 7.0 0.047 -85.3 66.8 7.0 0.047 0.0 CA
HOH
 2.116
4.164
 OD1
OD1
 CA
O
ASP B:87 B:182 3.0 0.02 -79.2 68.3 3.0 0.02 0.0 CA
HOH
 2.341
2.936
 OD1
OD2
 CA
O
4wq2 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:87 A:182 3.0 0.02 -89.6 70.2 3.0 0.02 0.0 CA
HOH
 2.307
2.853
 OD1
OD2
 CA
O
ASP B:87 B:182 7.0 0.047 -84.1 72.6 7.0 0.047 0.0 CA
HOH
 2.346
2.591
 OD1
OD2
 CA
O
4wq3 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:87 A:182 5.0 0.033 -86.8 68.6 5.0 0.033 0.0 CA
HOH
 2.280
2.765
 OD1
OD2
 CA
O
ASP B:87 B:182 3.0 0.02 -81.9 66.9 3.0 0.02 0.0 CA
HOH
 2.288
2.707
 OD1
OD2
 CA
O
5d69 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:87 A:182 4.0 0.027 -78.5 68.2 4.0 0.027 0.0 CA
HOH
 2.279
4.380
 OD1
OD1
 CA
O
ASP B:87 B:182 4.0 0.027 -80.1 67.6 4.0 0.027 0.0 CA
HOH
 2.351
2.805
 OD1
OD2
 CA
O
1df0 2 Q64537 92.35 6e-129 X-RAY
 2000-06-21 ASP B:98 B:98 6.0 0.04 -90.1 69.7 6.0 0.04 0.0 HOH
 2.368
 OD2
 O
1u5i 2 Q64537 92.35 6e-129 X-RAY
 2005-01-18 ASP B:98 B:98 10.0 0.067 -86.0 43.2 10.0 0.067 0.0 HOH
 3.007
 O
 O
3bow 2 Q64537 92.35 6e-129 X-RAY
 2008-11-25 ASP B:98 B:184 15.0 0.1 -83.8 71.5 15.0 0.1 0.0 CA
 2.324
 OD1
 CA
3df0 2 Q64537 92.35 6e-129 X-RAY
 2008-11-11 ASP B:98 B:184 5.0 0.033 -79.9 83.1 5.0 0.033 0.0 CA
 2.522
 OD2
 CA
1dvi 1 Q64537 91.8 7e-128 X-RAY
 1998-05-27 ASP A:98 A:184 16.0 0.107 -81.6 67.6 16.0 0.107 0.0 CA
HOH
 2.413
3.052
 OD1
OD2
 CA
O
ASP B:98 B:184 17.0 0.113 -91.4 67.0 17.0 0.113 0.0 CA
HOH
 2.324
2.632
 OD1
OD2
 CA
O
1alv 1 P04574 97.11 8e-126 X-RAY
 1998-06-03 ASP A:87 A:180 6.0 0.04 -84.8 64.9 6.0 0.04 0.0 CA
HOH
 2.184
4.361
 OD1
OD1
 CA
O
ASP B:87 B:180 5.0 0.033 -90.7 73.4 5.0 0.033 0.0 CA
HOH
 2.197
2.084
 OD1
OD2
 CA
H2
1alw 1 P04574 97.11 8e-126 X-RAY
 1998-06-10 ASP A:87 A:180 10.0 0.067 -83.7 68.4 10.0 0.067 0.0 CA
HOH
 2.112
4.109
 OD1
OD1
 CA
O
ASP B:87 B:180 3.0 0.02 -94.6 71.9 3.0 0.02 0.0 CA
HOH
 2.053
3.049
 OD1
OD2
 CA
O
1nx0 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:87 A:180 4.0 0.027 -90.0 67.3 4.0 0.027 0.0 CA
HOH
 2.324
2.858
 OD1
OD2
 CA
O
ASP B:87 B:480 18.0 0.12 -91.1 64.5 18.0 0.12 0.0 CA
HOH
 2.481
4.796
 OD1
OD2
 CA
O
1nx1 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:87 A:180 2.0 0.013 -88.3 75.2 2.0 0.013 0.0 CA
HOH
 2.274
2.580
 OD1
OD2
 CA
O
ASP B:87 B:480 4.0 0.027 -94.4 67.4 4.0 0.027 0.0 CA
 2.499
 OD1
 CA
1nx2 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:87 A:180 7.0 0.047 -86.5 67.4 7.0 0.047 0.0 CA
HOH
 2.331
4.964
 OD1
N
 CA
O
1nx3 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:87 A:180 6.0 0.04 -87.9 59.6 6.0 0.04 0.0 CA
HOH
 2.323
4.803
 OD1
N
 CA
O
4phn 1 P04574 97.11 8e-126 X-RAY
 2014-08-13 ASP A:87 A:180 3.0 0.02 -84.7 72.8 3.0 0.02 0.0 CA
HOH
 2.297
2.787
 OD1
OD2
 CA
O
ASP B:87 B:180 6.0 0.04 -85.8 68.4 6.0 0.04 0.0 CA
HOH
 2.264
2.928
 OD1
OD2
 CA
O
6qlb 1 P04632 92.49 1e-121 X-RAY
 2020-02-05 ASP A:87 A:87 6.0 0.04 -82.2 70.7 6.0 0.04 0.0 CA
HOH
 2.236
4.320
 OD1
OD1
 CA
O
ASP B:87 B:87 4.0 0.027 -82.9 69.1 4.0 0.027 0.0 CA
HOH
 2.373
2.665
 OD1
OD2
 CA
O
ASP C:87 C:87 10.0 0.067 -84.7 71.3 10.0 0.067 0.0 CA
HOH
 2.332
5.114
 OD1
OD1
 CA
O
ASP D:87 D:87 5.0 0.033 -85.3 69.4 5.0 0.033 0.0 CA
HOH
 2.039
4.087
 OD1
OD1
 CA
O
1aj5 1 Q64537 91.91 2e-120 X-RAY
 1998-05-20 ASP A:87 A:184 0.0 0.0 -94.7 58.0 0.0 0.0 0.0 HOH
 2.548
 OD2
 O
ASP B:87 B:184 1.0 0.007 -89.5 63.2 NA NA NA
1qxp 1 Q07009,P97571,505658 91.76 2e-117 X-RAY
 2004-02-03 GLU A:814 NA:NA DO NA DO DO DO NA NA NA
GLU B:814 B:807 182.0 0.958 T 135.3 -33.0 NA NA NA
1np8 1 Q64537 91.82 2e-109 X-RAY
 2003-11-18 ASP A:94 A:98 20.0 0.133 -84.0 73.3 19.0 0.127 0.006 B:Q64537:0.007
 CD
CD
CD
HOH
 6.603
2.075
9.640
2.770
 OD1
OD1
OD2
OD2
 CD
CD
CD
O
ASP B:94 B:598 20.0 0.133 -84.6 73.5 20.0 0.133 0.0 CD
CD
HOH
 1.979
9.492
3.202
 OD1
OD2
OD2
 CD
CD
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04632-f1 1 P04632 100.0 0.0 ASP A:182 A:182 18.0 0.12 -71.5 75.4