Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 36637203 . A C CCDS12489.1:NM_001003962.1:c.710gAc>gCc_NP_001003962.1:p.237D>A Homo sapiens calpain, small subunit 1 (CAPNS1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1kfu 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 ASP B:153 S:937 33.0 0.22 H -51.9 -37.8 33.0 0.22 0.0 HOH
 3.147
 OD1
 O
1kfx 2 P04632 100.0 1e-140 X-RAY
 2001-12-07 ASP B:153 S:937 18.0 0.12 H -40.7 -44.4 18.0 0.12 0.0 HOH
 4.328
 OD2
 O
4phj 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:142 A:237 22.0 0.147 H -57.3 -46.5 22.0 0.147 0.0 HOH
 2.558
 OD1
 O
ASP B:142 B:237 21.0 0.14 H -56.6 -45.0 21.0 0.14 0.0 HOH
 2.644
 OD2
 O
4phk 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:142 A:237 20.0 0.133 H -56.3 -44.4 20.0 0.133 0.0 HOH
 2.430
 OD2
 O
ASP B:142 B:237 18.0 0.12 H -56.7 -42.6 18.0 0.12 0.0 HOH
 2.615
 OD2
 O
4phm 1 P04632 100.0 2e-131 X-RAY
 2014-08-13 ASP A:142 A:237 20.0 0.133 H -51.8 -48.8 20.0 0.133 0.0 HOH
 2.594
 OD2
 O
ASP B:142 B:237 19.0 0.127 H -49.8 -47.9 19.0 0.127 0.0 HOH
 2.755
 OD2
 O
4wq2 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:142 A:237 20.0 0.133 H -57.0 -42.9 20.0 0.133 0.0 HOH
 2.744
 OD2
 O
ASP B:142 B:237 24.0 0.16 H -56.1 -46.3 24.0 0.16 0.0 EDO
HOH
 9.235
2.642
 C
OD2
 O2
O
4wq3 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:142 A:237 23.0 0.153 H -56.9 -51.8 23.0 0.153 0.0 HOH
 2.468
 OD1
 O
ASP B:142 B:237 21.0 0.14 H -53.7 -44.8 21.0 0.14 0.0 HOH
 2.687
 OD2
 O
5d69 1 P04632 100.0 2e-131 X-RAY
 2015-09-02 ASP A:142 A:237 21.0 0.14 H -58.4 -41.3 21.0 0.14 0.0 HOH
 2.760
 OD2
 O
ASP B:142 B:237 21.0 0.14 H -57.4 -45.0 21.0 0.14 0.0 HOH
 2.647
 OD2
 O
1df0 2 Q64537 92.35 6e-129 X-RAY
 2000-06-21 ASP B:153 B:153 20.0 0.133 H -64.6 -50.7 20.0 0.133 0.0 HOH
 5.600
 OD1
 O
1u5i 2 Q64537 92.35 6e-129 X-RAY
 2005-01-18 ASP B:153 B:153 21.0 0.14 H -61.9 -44.6 21.0 0.14 0.0 HOH
 3.340
 OD2
 O
3bow 2 Q64537 92.35 6e-129 X-RAY
 2008-11-25 ASP B:153 B:239 21.0 0.14 H -61.4 -41.1 21.0 0.14 0.0 HOH
 2.625
 OD2
 O
3df0 2 Q64537 92.35 6e-129 X-RAY
 2008-11-11 ASP B:153 B:239 22.0 0.147 H -54.1 -37.1 22.0 0.147 0.0
1dvi 1 Q64537 91.8 7e-128 X-RAY
 1998-05-27 ASP A:153 A:239 18.0 0.12 H -56.7 -49.6 18.0 0.12 0.0 HOH
 2.937
 OD1
 O
ASP B:153 B:239 19.0 0.127 H -57.0 -48.1 19.0 0.127 0.0 HOH
 3.113
 OD1
 O
1alv 1 P04574 97.11 8e-126 X-RAY
 1998-06-03 ASP A:142 A:235 23.0 0.153 H -62.6 -44.6 23.0 0.153 0.0 HOH
 2.578
 OD2
 H2
ASP B:142 B:235 22.0 0.147 H -61.6 -42.5 22.0 0.147 0.0 HOH
 2.980
 OD1
 O
1alw 1 P04574 97.11 8e-126 X-RAY
 1998-06-10 ASP A:142 A:235 20.0 0.133 H -64.1 -43.0 20.0 0.133 0.0 HOH
 2.670
 OD2
 O
ASP B:142 B:235 22.0 0.147 H -65.2 -42.4 22.0 0.147 0.0 HOH
 2.401
 OD2
 O
1nx0 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:142 A:235 20.0 0.133 H -64.5 -48.5 3.0 0.02 0.113 E:None:0.113
 HOH
 5.485
 OD1
 O
ASP B:142 B:535 27.0 0.18 H -58.3 -48.1 27.0 0.18 0.0 HOH
 2.856
 OD1
 O
1nx1 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:142 A:235 26.0 0.173 H -59.7 -44.6 26.0 0.173 0.0 HOH
 2.505
 OD1
 O
ASP B:142 B:535 26.0 0.173 H -54.0 -48.4 26.0 0.173 0.0 HOH
 2.605
 OD2
 O
1nx2 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:142 A:235 22.0 0.147 H -56.6 -41.8 22.0 0.147 0.0 HOH
 2.697
 OD2
 O
1nx3 1 P04574 97.11 8e-126 X-RAY
 2003-08-19 ASP A:142 A:235 21.0 0.14 H -55.7 -43.7 21.0 0.14 0.0 HOH
 2.678
 OD2
 O
4phn 1 P04574 97.11 8e-126 X-RAY
 2014-08-13 ASP A:142 A:235 19.0 0.127 H -51.7 -47.1 19.0 0.127 0.0 HOH
 2.622
 OD1
 O
ASP B:142 B:235 21.0 0.14 H -56.3 -41.5 21.0 0.14 0.0 HOH
 2.658
 OD2
 O
6qlb 1 P04632 92.49 1e-121 X-RAY
 2020-02-05 ASP A:142 A:142 18.0 0.12 H -58.3 -50.9 18.0 0.12 0.0 HOH
 2.963
 OD1
 O
ASP B:142 B:142 19.0 0.127 H -59.6 -49.9 19.0 0.127 0.0 HOH
 2.849
 OD2
 O
ASP C:142 C:142 19.0 0.127 H -60.3 -49.2 19.0 0.127 0.0 P4G
HOH
 6.690
2.478
 OD2
OD2
 O2
O
ASP D:142 D:142 16.0 0.107 H -61.1 -47.3 16.0 0.107 0.0 P4G
HOH
 6.735
2.611
 OD2
OD2
 C6
O
1aj5 1 Q64537 91.91 2e-120 X-RAY
 1998-05-20 ASP A:142 A:239 20.0 0.133 H -61.4 -39.0 20.0 0.133 0.0 HOH
 2.803
 OD2
 O
ASP B:142 B:239 15.0 0.1 H -58.7 -44.9 NA NA NA
1qxp 1 Q07009,P97571,505658 91.76 2e-117 X-RAY
 2004-02-03 ASP A:869 A:862 13.0 0.087 H -66.8 -57.6 13.0 0.087 0.0 HOH
 5.403
 OD2
 O
ASP B:869 B:862 12.0 0.08 H -82.3 -77.9 NA NA NA
1np8 1 Q64537 91.82 2e-109 X-RAY
 2003-11-18 ASP A:149 A:153 12.0 0.08 H -52.8 -52.7 12.0 0.08 0.0 HOH
 2.711
 OD1
 O
ASP B:149 B:653 6.0 0.04 H -66.6 -43.6 6.0 0.04 0.0 HOH
 2.686
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04632-f1 1 P04632 100.0 0.0 ASP A:237 A:237 1.0 0.007 H -53.9 -50.0