Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41858709 . A C CCDS33031.1:NM_000660.4:c.241Tac>Gac_NP_000651.3:p.81Y>D Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 TYR C:54 C:52 137.0 0.596 H -67.8 -34.6 15.0 0.065 0.531 D:P01137:0.53
 NAG
NAG
 5.769
9.863
 CE2
CE2
 O6
C8
TYR D:54 D:52 146.0 0.635 H -66.4 -32.3 19.0 0.083 0.552 C:P01137:0.552
 NAG
NAG
 6.084
9.951
 CD2
CD2
 O6
C1
TYR G:54 G:52 135.0 0.587 H -70.0 -35.3 19.0 0.083 0.504 H:P01137:0.504
 NAG
NAG
 4.581
7.319
 CE2
CE2
 O6
C8
TYR H:54 H:52 144.0 0.626 H -66.2 -32.2 20.0 0.087 0.539 G:P01137:0.539
 NAG
NAG
 6.047
9.996
 CD2
CD2
 O6
C1
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 TYR A:54 A:52 136.0 0.591 H -66.9 -41.3 14.0 0.061 0.53 A:P01137:0.53
 NAG
NAG
 5.239
8.682
 CE2
CE2
 O6
C8
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 TYR C:54 D:52 72.0 NA H -53.5 -47.2 72.0 NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 TYR A:54 A:52 134.0 0.583 H -56.7 -42.5 8.0 0.035 0.548 B:P07200:0.548
 NAG
 6.501
 C
 C1
TYR B:54 B:52 135.0 0.587 H -56.7 -42.6 10.0 0.043 0.544 A:P07200:0.543
 NAG
NAG
 6.500
9.245
 C
CE2
 C1
O7
TYR C:54 C:52 132.0 0.574 H -56.6 -42.6 NA NA NA
TYR D:54 D:52 135.0 0.587 H -56.8 -42.5 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 TYR A:54 A:52 139.0 0.604 H -66.8 -28.6 9.0 0.039 0.565 B:P07200:0.565
TYR B:54 B:52 124.0 0.539 H -66.7 -36.0 6.0 0.026 0.513 A:P07200:0.513
 NAG
 6.063
 CD2
 C1
TYR C:54 C:52 125.0 0.543 H -66.6 -34.9 NA NA NA
TYR D:54 D:52 129.0 0.561 H -64.6 -34.2 NA NA NA
6gff 1 P01137 100.0 0.0 X-RAY
 2018-11-07 TYR A:52 A:81 132.0 0.574 H -64.0 -32.3 24.0 0.104 0.47 D:P01137:0.47
TYR C:52 C:81 136.0 0.591 H -66.3 -33.6 12.0 0.052 0.539 B:P01137:0.539
TYR E:52 E:81 152.0 0.661 H -67.0 -34.5 NA NA NA
TYR G:52 G:81 123.0 0.535 H -66.2 -34.3 NA NA NA
6p7j 1 P01137 100.0 0.0 X-RAY
 2020-03-11 TYR A:52 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 TYR A:81 A:81 16.0 0.07 H -62.8 -49.6