Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42471895 . C A CCDS12594.1:NM_152296.4:c.2840gGg>gTg_NP_689509.1:p.947G>V Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLY A:950 A:950 0.0 0.0 H -57.2 -41.1 0.0 0.0 0.0 PC1
 7.688
 O
 C2D
GLY D:950 C:950 1.0 0.013 H -55.8 -39.5 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 GLY A:950 A:950 1.0 0.013 H -60.3 -47.7 1.0 0.013 0.0 PC1
 7.366
 O
 C2D
GLY D:950 C:950 0.0 0.0 H -56.5 -39.1 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 GLY A:955 A:955 0.0 0.0 H -54.1 -51.1 0.0 0.0 0.0 CLR
 8.911
 C
 C26
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 GLY A:955 A:950 0.0 0.0 H -66.0 -45.5 0.0 0.0 0.0 CLR
 7.598
 C
 C26
GLY D:955 C:950 0.0 0.0 H -66.7 -46.5 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 GLY A:955 A:950 0.0 0.0 H -58.2 -47.0 0.0 0.0 0.0
GLY D:955 C:950 0.0 0.0 H -57.4 -47.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLY A:955 A:950 0.0 0.0 H -49.6 -45.2 0.0 0.0 0.0
GLY D:955 C:950 0.0 0.0 H -49.4 -46.9 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 GLY A:955 A:950 0.0 0.0 H -59.2 -50.8 0.0 0.0 0.0
GLY D:955 C:950 0.0 0.0 H -59.0 -51.1 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 GLY A:955 A:950 0.0 0.0 H -62.6 -38.9 0.0 0.0 0.0
GLY D:955 C:950 0.0 0.0 H -63.8 -38.5 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -63.5 -29.4 0.0 0.0 0.0 PCW
 7.209
 CA
 O31
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -65.1 -38.3 0.0 0.0 0.0 PCW
 8.967
 CA
 O31
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -61.0 -43.9 0.0 0.0 0.0 PCW
 6.823
 CA
 O31
GLY C:950 C:950 0.0 0.0 H -61.9 -42.8 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -61.1 -44.1 0.0 0.0 0.0 PCW
 7.556
 CA
 C32
GLY D:950 C:950 0.0 0.0 H -62.5 -42.6 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -63.2 -31.1 0.0 0.0 0.0 PCW
 7.075
 CA
 O31
GLY D:950 C:950 0.0 0.0 H -64.0 -36.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -62.9 -42.9 0.0 0.0 0.0 PCW
 8.688
 CA
 O31
GLY D:950 C:950 0.0 0.0 H -63.1 -42.4 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -60.2 -44.3 0.0 0.0 0.0 PCW
 8.326
 CA
 O31
GLY D:950 C:950 0.0 0.0 H -60.4 -43.4 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -61.1 -43.8 0.0 0.0 0.0 PCW
 6.878
 N
 O31
GLY D:950 C:950 0.0 0.0 H -62.1 -42.2 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -63.3 -33.6 0.0 0.0 0.0 PCW
 6.622
 CA
 O31
GLY D:950 C:950 0.0 0.0 H -64.0 -36.6 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 GLY A:950 A:950 0.0 0.0 H -62.6 -43.4 0.0 0.0 0.0 PCW
 6.413
 CA
 O31
GLY D:950 C:950 0.0 0.0 H -62.6 -41.8 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 GLY A:932 A:950 2.0 0.027 H 172.7 -41.7 2.0 0.027 0.0
GLY D:932 C:950 0.0 0.0 H -134.7 -23.3 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 GLY A:932 A:950 0.0 0.0 H -47.6 -45.4 0.0 0.0 0.0
GLY D:932 C:950 0.0 0.0 H -47.5 -45.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLY A:926 A:950 0.0 0.0 H -64.6 -42.0 0.0 0.0 0.0
GLY D:926 C:950 0.0 0.0 H -64.8 -41.7 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0 HOH
 5.485
 O
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 GLY A:962 A:957 0.0 0.0 H -60.8 -45.7 0.0 0.0 0.0 HOH
 5.518
 O
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.6 -44.5 0.0 0.0 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.8 -44.3 0.0 0.0 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.5 0.0 0.0 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.3 0.0 0.0 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.8 -44.4 0.0 0.0 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.3 0.0 0.0 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.4 0.0 0.0 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.3 0.0 0.0 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.7 -44.3 0.0 0.0 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -55.8 -44.3 0.0 0.0 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 GLY A:962 A:957 0.0 0.0 H -54.0 -48.7 0.0 0.0 0.0 HOH
 5.538
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 GLY A:947 A:947 0.0 0.0 H -55.5 -47.7
af-p50993-f1 1 P50993 88.81 0.0 GLY A:954 A:954 0.0 0.0 H -56.1 -48.5
af-p05023-f1 1 P05023 88.03 0.0 GLY A:957 A:957 0.0 0.0 H -55.5 -48.4