Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42472976 . C A CCDS12594.1:NM_152296.4:c.2780tGc>tTc_NP_689509.1:p.927C>F Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 CYS A:930 A:930 1.0 0.007 T -85.0 27.2 1.0 0.007 0.0 NA
 7.206
 SG
 NA
CYS D:930 C:930 7.0 0.052 T -79.9 13.3 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 CYS A:930 A:930 1.0 0.007 T -86.4 27.2 1.0 0.007 0.0 NA
 6.935
 SG
 NA
CYS D:930 C:930 6.0 0.044 T -80.0 11.8 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 CYS A:935 A:935 4.0 0.03 H -76.1 -20.0 4.0 0.03 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 CYS A:935 A:930 1.0 0.007 H -74.2 -20.9 1.0 0.007 0.0 NA
 6.784
 SG
 NA
CYS D:935 C:930 0.0 0.0 H -74.2 -20.6 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 CYS A:935 A:930 5.0 0.037 H -79.0 -13.1 5.0 0.037 0.0
CYS D:935 C:930 5.0 0.037 H -79.0 -13.3 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 CYS A:935 A:930 2.0 0.015 H -81.0 -21.1 2.0 0.015 0.0
CYS D:935 C:930 2.0 0.015 H -81.0 -21.0 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 CYS A:935 A:930 4.0 0.03 H -74.7 -16.4 4.0 0.03 0.0
CYS D:935 C:930 4.0 0.03 H -75.4 -16.4 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 CYS A:935 A:930 5.0 0.037 H -70.4 -17.7 5.0 0.037 0.0
CYS D:935 C:930 4.0 0.03 H -69.7 -17.2 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 6.0 0.044 H -78.6 -8.7 6.0 0.044 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 7.0 0.052 H -76.9 -11.1 7.0 0.052 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 3.0 0.022 H -73.0 -21.0 3.0 0.022 0.0
CYS C:930 C:930 4.0 0.03 H -71.0 -20.7 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 3.0 0.022 H -73.8 -21.5 3.0 0.022 0.0
CYS D:930 C:930 4.0 0.03 H -71.1 -21.7 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 6.0 0.044 H -73.4 -17.5 6.0 0.044 0.0
CYS D:930 C:930 6.0 0.044 H -73.1 -16.8 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 1.0 0.007 H -82.8 -19.1 1.0 0.007 0.0
CYS D:930 C:930 1.0 0.007 H -82.7 -18.0 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 5.0 0.037 H -71.7 -20.5 5.0 0.037 0.0
CYS D:930 C:930 5.0 0.037 H -71.2 -19.9 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 2.0 0.015 H -73.6 -21.4 2.0 0.015 0.0
CYS D:930 C:930 4.0 0.03 H -71.1 -21.0 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 3.0 0.022 H -72.9 -20.8 3.0 0.022 0.0
CYS D:930 C:930 4.0 0.03 H -72.6 -19.3 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 CYS A:930 A:930 2.0 0.015 H -72.8 -22.5 2.0 0.015 0.0
CYS D:930 C:930 3.0 0.022 H -71.3 -22.8 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 CYS A:912 A:930 9.0 0.067 S -100.0 -4.9 9.0 0.067 0.0
CYS D:912 C:930 8.0 0.059 S -84.1 44.5 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 CYS A:912 A:930 3.0 0.022 S -90.9 24.2 3.0 0.022 0.0
CYS D:912 C:930 3.0 0.022 S -90.1 23.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 CYS A:906 A:930 0.0 0.0 S -94.5 -19.3 0.0 0.0 0.0
CYS D:906 C:930 0.0 0.0 S -94.9 -19.9 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0 HOH
 7.375
 O
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 CYS A:942 A:937 1.0 0.007 H -78.3 -9.3 1.0 0.007 0.0 HOH
 8.969
 CB
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.3 1.0 0.007 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.2 1.0 0.007 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.2 1.0 0.007 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.4 1.0 0.007 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.2 1.0 0.007 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.2 1.0 0.007 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.3 1.0 0.007 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.2 1.0 0.007 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.6 -8.2 1.0 0.007 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 1.0 0.007 T -68.5 -8.4 1.0 0.007 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 CYS A:942 A:937 0.0 0.0 H -70.5 -12.5 0.0 0.0 0.0 HOH
 7.460
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 CYS A:927 A:927 4.0 0.03 H -65.3 -19.9
af-p50993-f1 1 P50993 88.81 0.0 CYS A:934 A:934 4.0 0.03 H -65.4 -20.2
af-p05023-f1 1 P05023 88.03 0.0 CYS A:937 A:937 4.0 0.03 H -61.8 -22.6