Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42474363 . A C CCDS12594.1:NM_152296.4:c.2516cTc>cGc_NP_689509.1:p.839L>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:842 A:842 1.0 0.006 H -82.5 -27.9 1.0 0.006 0.0 PC1
CLR
 6.345
7.075
 CD2
C
 C32
C6
LEU D:842 C:842 1.0 0.006 H -83.8 -41.6 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LEU A:842 A:842 1.0 0.006 H -76.7 -31.7 1.0 0.006 0.0 CLR
PC1
 6.712
6.620
 C
CD2
 C6
C32
LEU D:842 C:842 2.0 0.012 H -84.8 -32.6 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 LEU A:847 A:847 1.0 0.006 H -60.6 -48.4 1.0 0.006 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 LEU A:847 A:842 1.0 0.006 H -56.2 -40.5 1.0 0.006 0.0
LEU D:847 C:842 1.0 0.006 H -56.3 -40.1 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 LEU A:847 A:842 0.0 0.0 H -56.7 -45.7 0.0 0.0 0.0 17F
17F
 6.649
6.694
 C
N
 C18
O2
LEU D:847 C:842 1.0 0.006 H -57.0 -45.8 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:847 A:842 1.0 0.006 H -58.6 -55.3 1.0 0.006 0.0
LEU D:847 C:842 0.0 0.0 H -57.3 -54.3 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LEU A:847 A:842 1.0 0.006 H -64.9 -50.7 1.0 0.006 0.0 17F
17F
 7.808
6.435
 N
N
 O2
O4
LEU D:847 C:842 1.0 0.006 H -64.7 -50.5 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 LEU A:847 A:842 0.0 0.0 H -62.6 -42.1 0.0 0.0 0.0 PCW
CLR
 9.469
8.757
 N
C
 O4P
C6
LEU D:847 C:842 0.0 0.0 H -62.9 -40.2 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -63.4 -39.5 0.0 0.0 0.0 PCW
 6.609
 C
 O31
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -62.5 -40.7 0.0 0.0 0.0 PCW
CLR
 8.233
7.752
 C
C
 O31
C6
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -66.6 -36.9 0.0 0.0 0.0 PCW
 7.439
 N
 O2P
LEU C:842 C:842 0.0 0.0 H -68.7 -39.1 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -66.6 -38.4 0.0 0.0 0.0 PCW
 8.209
 N
 O4P
LEU D:842 C:842 0.0 0.0 H -68.9 -37.6 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -61.7 -38.4 0.0 0.0 0.0 PCW
CLR
 8.312
8.544
 N
C
 C5
C6
LEU D:842 C:842 1.0 0.006 H -62.7 -38.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -60.5 -46.3 0.0 0.0 0.0 PCW
CLR
 7.935
8.728
 N
C
 C5
C6
LEU D:842 C:842 0.0 0.0 H -61.0 -46.3 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -60.3 -44.8 0.0 0.0 0.0 PCW
 8.212
 N
 O4P
LEU D:842 C:842 1.0 0.006 H -60.0 -42.9 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -81.8 -38.2 0.0 0.0 0.0 PCW
 7.759
 N
 O2P
LEU D:842 C:842 0.0 0.0 H -91.3 -40.7 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -61.5 -44.8 0.0 0.0 0.0 PCW
CLR
 8.194
8.753
 N
C
 C5
C6
LEU D:842 C:842 1.0 0.006 H -61.9 -43.5 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LEU A:842 A:842 0.0 0.0 H -66.3 -35.9 0.0 0.0 0.0 PCW
CLR
 8.050
8.633
 N
C
 C5
C6
LEU D:842 C:842 0.0 0.0 H -68.4 -36.4 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 LEU A:824 A:842 2.0 0.012 H -71.3 -68.0 2.0 0.012 0.0 PC1
 7.473
 C
 C14
LEU D:824 C:842 1.0 0.006 H -40.6 -60.0 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 LEU A:824 A:842 0.0 0.0 H -88.3 -51.4 0.0 0.0 0.0 CLR
 7.024
 C
 C6
LEU D:824 C:842 0.0 0.0 H -87.6 -51.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LEU A:818 A:842 0.0 0.0 H -70.1 -28.9 0.0 0.0 0.0
LEU D:818 C:842 1.0 0.006 H -69.4 -29.2 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
HOH
 6.793
8.254
 C
CD1
 C6
O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 LEU A:854 A:849 0.0 0.0 H -89.8 -36.8 0.0 0.0 0.0 CLR
HOH
 6.986
8.784
 C
CD1
 C6
O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.4 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.792
 C
 C6
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.2 -46.5 0.0 0.0 0.0 CLR
 6.794
 C
 C6
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.2 -46.7 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.6 0.0 0.0 0.0 CLR
 6.792
 C
 C6
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.4 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.794
 C
 C6
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.794
 C
 C6
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.792
 C
 C6
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.794
 C
 C6
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.3 -46.5 0.0 0.0 0.0 CLR
 6.794
 C
 C6
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -69.2 -46.6 0.0 0.0 0.0 CLR
 6.793
 C
 C6
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LEU A:854 A:849 0.0 0.0 H -68.0 -47.7 0.0 0.0 0.0 CLR
HOH
 6.715
8.060
 C
CD1
 C6
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 LEU A:839 A:839 0.0 0.0 H -63.0 -47.9
af-p50993-f1 1 P50993 88.81 0.0 LEU A:846 A:846 1.0 0.006 H -63.3 -47.5
af-p05023-f1 1 P05023 88.03 0.0 LEU A:849 A:849 0.0 0.0 H -63.2 -48.5