Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42485662 . T A CCDS12594.1:NM_152296.4:c.1429Aaa>Taa_NP_689509.1:p.477K>* Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LYS A:480 A:480 16.0 0.08 61.3 25.3 16.0 0.08 0.0 MG
ALF
MG
ADP
HOH
 8.376
6.354
9.996
3.038
9.272
 NZ
NZ
NZ
NZ
CA
 MG
F3
MG
O2A
O
LYS D:480 C:480 17.0 0.085 69.4 24.3 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 LYS A:480 A:480 14.0 0.07 62.8 32.7 14.0 0.07 0.0 MG
ALF
ADP
HOH
 8.664
6.574
2.745
9.032
 NZ
NZ
NZ
CA
 MG
F3
O1A
O
LYS D:480 C:480 17.0 0.085 72.5 30.2 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 LYS A:485 A:485 71.0 0.355 43.8 40.2 71.0 0.355 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 LYS A:485 A:480 25.0 0.125 T 75.8 6.7 25.0 0.125 0.0 ADP
ALF
 3.961
7.402
 CD
NZ
 C5'
F4
LYS D:485 C:480 23.0 0.115 T 74.8 6.6 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 LYS A:485 A:480 89.0 0.445 41.7 39.2 89.0 0.445 0.0
LYS D:485 C:480 102.0 0.51 56.1 53.0 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LYS A:485 A:480 25.0 0.125 T 43.7 38.9 25.0 0.125 0.0
LYS D:485 C:480 25.0 0.125 T 43.9 39.4 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 LYS A:485 A:480 93.0 0.465 43.2 43.0 93.0 0.465 0.0
LYS D:485 C:480 96.0 0.48 43.1 42.8 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 LYS A:485 A:480 94.0 0.47 -52.1 105.9 94.0 0.47 0.0
LYS D:485 C:480 93.0 0.465 -50.0 106.3 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 95.0 0.475 -42.0 111.5 95.0 0.475 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 90.0 0.45 -46.2 115.8 90.0 0.45 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 99.0 0.495 -48.5 107.9 99.0 0.495 0.0
LYS C:480 C:480 94.0 0.47 -52.0 106.1 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 102.0 0.51 -50.0 108.0 102.0 0.51 0.0
LYS D:480 C:480 93.0 0.465 -51.8 107.2 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 98.0 0.49 -41.8 106.7 98.0 0.49 0.0
LYS D:480 C:480 101.0 0.505 -42.3 109.5 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 95.0 0.475 -63.1 113.7 95.0 0.475 0.0
LYS D:480 C:480 93.0 0.465 -63.2 114.2 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 79.0 0.395 -58.1 137.3 79.0 0.395 0.0
LYS D:480 C:480 79.0 0.395 -58.1 139.4 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 102.0 0.51 -48.6 107.9 102.0 0.51 0.0
LYS D:480 C:480 91.0 0.455 -51.2 107.2 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 98.0 0.49 -58.6 129.8 98.0 0.49 0.0
LYS D:480 C:480 99.0 0.495 -59.7 130.0 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 LYS A:480 A:480 99.0 0.495 -48.7 110.0 99.0 0.495 0.0
LYS D:480 C:480 100.0 0.5 -50.4 109.7 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 LYS A:462 A:480 84.0 0.42 55.8 156.5 84.0 0.42 0.0
LYS D:462 C:480 84.0 0.42 55.6 156.9 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 LYS A:462 A:480 81.0 0.405 54.6 16.6 81.0 0.405 0.0
LYS D:462 C:480 82.0 0.41 54.4 16.3 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LYS A:456 A:480 92.0 0.46 69.8 11.0 92.0 0.46 0.0
LYS D:456 C:480 92.0 0.46 70.3 10.3 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0 HOH
 7.034
 CG
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 LYS A:492 A:487 98.0 0.49 53.6 29.1 98.0 0.49 0.0 HOH
 8.508
 O
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 23.9 89.0 0.445 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.4 24.1 89.0 0.445 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.6 24.0 89.0 0.445 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.5 23.9 90.0 0.45 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.6 24.0 90.0 0.45 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.6 23.9 90.0 0.45 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.6 23.9 89.0 0.445 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.6 23.9 89.0 0.445 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.5 24.0 90.0 0.45 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.4 24.0 90.0 0.45 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.5 24.0 90.0 0.45 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.1 89.0 0.445 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 90.0 0.45 60.5 24.1 90.0 0.45 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.6 24.0 89.0 0.445 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 89.0 0.445 60.5 24.0 89.0 0.445 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 LYS A:492 A:487 91.0 0.455 58.9 21.1 91.0 0.455 0.0 HOH
 7.084
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 LYS A:477 A:477 85.0 0.425 59.8 20.1
af-p50993-f1 1 P50993 88.81 0.0 LYS A:485 A:485 85.0 0.425 58.7 22.0
af-p05023-f1 1 P05023 88.03 0.0 LYS A:487 A:487 84.0 0.42 59.9 21.3