Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42489240 . C A CCDS12594.1:NM_152296.4:c.823Gcc>Tcc_NP_689509.1:p.275A>S Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:278 A:278 12.0 0.104 H -60.5 -45.7 12.0 0.104 0.0 HOH
 3.390
 O
 O
ALA D:278 C:278 18.0 0.157 H -63.3 -24.4 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 ALA A:278 A:278 14.0 0.122 H -64.9 -43.7 14.0 0.122 0.0 EFO
 4.223
 O
 C51
ALA D:278 C:278 16.0 0.139 H -61.9 -28.2 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 ALA A:283 A:283 20.0 0.174 H -67.0 -36.0 20.0 0.174 0.0
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 ALA A:283 A:278 26.0 0.226 H -65.7 -31.3 26.0 0.226 0.0
ALA D:283 C:278 26.0 0.226 H -65.9 -31.2 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 ALA A:283 A:278 21.0 0.183 H -60.7 -41.6 21.0 0.183 0.0 17F
 9.647
 O
 O5
ALA D:283 C:278 24.0 0.209 H -60.7 -41.4 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:283 A:278 26.0 0.226 H -62.3 -39.8 26.0 0.226 0.0
ALA D:283 C:278 28.0 0.243 H -63.1 -40.0 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 ALA A:283 A:278 20.0 0.174 H -61.8 -40.0 20.0 0.174 0.0 17F
 9.804
 O
 O4
ALA D:283 C:278 28.0 0.243 H -62.1 -40.0 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 ALA A:283 A:278 22.0 0.191 H -66.8 -34.2 22.0 0.191 0.0 PCW
 8.813
 O
 C6
ALA D:283 C:278 26.0 0.226 H -66.1 -34.4 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 27.0 0.235 H -64.4 -34.7 27.0 0.235 0.0
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 27.0 0.235 H -65.5 -36.2 27.0 0.235 0.0
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 23.0 0.2 H -65.3 -42.8 23.0 0.2 0.0
ALA C:278 C:278 23.0 0.2 H -65.2 -42.7 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 24.0 0.209 H -65.4 -42.5 24.0 0.209 0.0
ALA D:278 C:278 22.0 0.191 H -64.9 -43.0 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 25.0 0.217 H -68.3 -32.5 25.0 0.217 0.0
ALA D:278 C:278 24.0 0.209 H -67.6 -32.0 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 26.0 0.226 H -65.5 -37.7 26.0 0.226 0.0 PCW
 9.484
 O
 C6
ALA D:278 C:278 25.0 0.217 H -65.3 -36.7 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 25.0 0.217 H -65.8 -38.5 25.0 0.217 0.0 PCW
 8.313
 O
 C6
ALA D:278 C:278 24.0 0.209 H -65.1 -37.7 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 24.0 0.209 H -65.1 -42.7 24.0 0.209 0.0
ALA D:278 C:278 24.0 0.209 H -64.7 -42.9 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 23.0 0.2 H -65.3 -37.2 23.0 0.2 0.0
ALA D:278 C:278 24.0 0.209 H -65.1 -35.4 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 ALA A:278 A:278 23.0 0.2 H -64.8 -43.8 23.0 0.2 0.0 PCW
 9.273
 O
 C6
ALA D:278 C:278 22.0 0.191 H -64.8 -43.2 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 ALA A:260 A:278 14.0 0.122 H -75.6 -17.5 14.0 0.122 0.0
ALA D:260 C:278 25.0 0.217 H -55.2 -21.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 ALA A:260 A:278 5.0 0.043 H -62.6 -15.8 5.0 0.043 0.0
ALA D:260 C:278 8.0 0.07 H -51.5 -15.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ALA A:254 A:278 18.0 0.157 H -61.6 -31.5 18.0 0.157 0.0
ALA D:254 C:278 18.0 0.157 H -57.2 -36.6 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 ALA A:290 A:285 3.0 0.026 H -59.8 -46.3 3.0 0.026 0.0 HOH
 3.483
 CB
 O
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 ALA A:290 A:285 12.0 0.104 H -53.8 -46.1 12.0 0.104 0.0 HOH
 7.300
 CA
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.8 -46.2 3.0 0.026 0.0
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.7 -46.4 3.0 0.026 0.0
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.7 -46.4 3.0 0.026 0.0
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.9 -46.2 3.0 0.026 0.0
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.8 -46.3 3.0 0.026 0.0
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.9 -46.2 2.0 0.017 0.0
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.7 -46.4 3.0 0.026 0.0
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.8 -46.3 2.0 0.017 0.0
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.8 -46.3 2.0 0.017 0.0
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.8 -46.3 3.0 0.026 0.0
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.8 -46.4 2.0 0.017 0.0
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.8 -46.3 2.0 0.017 0.0
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.7 -46.3 2.0 0.017 0.0
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.9 -46.3 2.0 0.017 0.0
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.9 -46.3 2.0 0.017 0.0
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.7 -46.3 2.0 0.017 0.0
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.7 -46.4 3.0 0.026 0.0
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 2.0 0.017 H -59.8 -46.3 2.0 0.017 0.0
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -59.8 -46.4 3.0 0.026 0.0
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 ALA A:290 A:285 3.0 0.026 H -60.7 -43.5 3.0 0.026 0.0 HOH
 3.392
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 ALA A:275 A:275 21.0 0.183 H -63.9 -39.4
af-p50993-f1 1 P50993 88.81 0.0 ALA A:283 A:283 25.0 0.217 H -64.5 -40.2
af-p05023-f1 1 P05023 88.03 0.0 ALA A:285 A:285 22.0 0.191 H -63.5 -42.5