Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 49459056 . G A CCDS12742.1:NM_138761.3:c.199Ggg>Agg_NP_620116.1:p.67G>R Homo sapiens BCL2 associated X, apoptosis regulator (BAX), transcript variant alpha, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2lr1 1 Q07812 100.0 2e-140 NMR
 2012-12-05 GLY A:67 A:67 3.0 0.04 H -61.1 -45.4 3.0 0.04 0.0
4s0p 1 Q07812 99.48 3e-139 X-RAY
 2016-07-20 ARG A:67 A:67 6.0 0.027 H -56.4 -25.2 6.0 0.027 0.0
ARG B:67 B:67 16.0 0.071 H -46.0 -23.7 NA NA NA
6eb6 1 Q07812 99.48 4e-139 X-RAY
 2019-04-10 GLY A:67 A:67 1.0 0.013 H -58.3 -40.4 1.0 0.013 0.0 HOH
 5.070
 O
 O
4s0o 1 Q07812 99.48 6e-139 X-RAY
 2016-07-20 GLY A:67 A:67 0.0 0.0 H -58.0 -48.3 0.0 0.0 0.0 HOH
 6.181
 O
 O
GLY B:67 B:67 0.0 0.0 H -63.4 -40.6 0.0 0.0 0.0 HOH
 5.407
 O
 O
5w5x 3 Q07812 98.44 1e-136 X-RAY
 2018-06-27 GLY C:67 A:67 6.0 0.08 H -60.7 -45.8 6.0 0.08 0.0 HOH
 4.761
 O
 O
5w60 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 GLY A:67 A:67 0.0 0.0 H -60.9 -42.1 0.0 0.0 0.0 HOH
 3.663
 CA
 O
5w61 1 Q07812 98.44 1e-136 X-RAY
 2018-06-27 GLY A:67 A:67 1.0 0.013 H -61.5 -39.4 1.0 0.013 0.0 HOH
 5.440
 O
 O
5w62 1 Q07813 91.15 3e-125 X-RAY
 2018-06-27 GLY A:67 A:67 1.0 0.013 H -57.1 -49.7 1.0 0.013 0.0 HOH
 7.632
 C
 O
4bd2 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 GLY A:67 A:67 1.0 0.013 H -55.8 -43.4 1.0 0.013 0.0 HOH
 5.212
 O
 O
4bd6 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 GLY A:67 A:67 1.0 0.013 H -55.7 -43.3 1.0 0.013 0.0
4bd7 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 GLY A:67 A:67 0.0 0.0 H -56.3 -41.0 0.0 0.0 0.0 HOH
 5.689
 O
 O
GLY B:67 B:67 0.0 0.0 H -77.4 -24.1 0.0 0.0 0.0
GLY C:67 C:67 4.0 0.053 H -86.3 -12.0 NA NA NA
GLY D:67 D:67 0.0 0.0 H -56.9 -67.1 NA NA NA
4bd8 1 Q07812 98.83 1e-122 X-RAY
 2013-02-13 GLY A:67 A:67 0.0 0.0 H -61.2 -44.1 0.0 0.0 0.0 HOH
 3.321
 C
 O
GLY B:67 B:67 0.0 0.0 H -63.9 -44.8 0.0 0.0 0.0 HOH
 3.433
 C
 O
GLY C:67 C:67 0.0 0.0 H -59.2 -56.3 NA NA NA
GLY D:67 D:67 0.0 0.0 H -63.0 -38.8 NA NA NA
4zii 1 Q07812 98.82 1e-121 X-RAY
 2015-07-22 GLY A:67 A:67 0.0 0.0 H -63.4 -42.1 0.0 0.0 0.0 HOH
 5.459
 O
 O
4zie 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 GLY A:67 A:67 0.0 0.0 H -56.5 -43.4 0.0 0.0 0.0 HOH
 4.497
 CA
 O
4zif 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 GLY A:67 A:67 0.0 0.0 H -55.8 -42.7 0.0 0.0 0.0
4zig 1 Q07812 98.2 2e-118 X-RAY
 2015-07-22 GLY A:67 A:67 0.0 0.0 H -61.0 -39.8 0.0 0.0 0.0 HOH
 7.144
 O
 O
4zih 1 Q07812 98.78 2e-116 X-RAY
 2015-07-22 GLY A:67 A:67 0.0 0.0 H -56.3 -43.3 0.0 0.0 0.0
5w5z 3 Q07812 98.14 3e-113 X-RAY
 2018-06-27 GLY C:36 A:67 12.0 0.16 H -66.6 -40.1 12.0 0.16 0.0 HOH
 5.759
 O
 O
6l8v 1 Q07812 93.75 4e-48 NMR
 2020-11-11 GLY A:20 A:67 45.0 0.6 H -68.8 -48.1 15.0 0.2 0.4 B:Q07812:0.4
GLY B:20 B:67 40.0 0.533 H -62.0 -48.2 8.0 0.107 0.426 A:Q07812:0.427
4bdu 1 P42212,Q07812 97.37 4e-45 X-RAY
 2013-02-13 GLY A:248 A:1067 34.0 0.453 H -77.1 -20.8 0.0 0.0 0.453 B:P42212+Q07812:0.453
GLY B:248 B:1067 35.0 0.467 H -77.2 -21.4 0.0 0.0 0.467 A:P42212+Q07812:0.467
 HOH
 7.515
 O
 O
GLY C:248 C:1067 34.0 0.453 H -77.4 -21.4 NA NA NA
GLY D:248 D:1067 36.0 0.48 H -76.6 -21.1 NA NA NA
3pk1 2 Q07812 100.0 2e-17 X-RAY
 2010-12-29 GLY B:20 B:67 37.0 0.493 H -65.0 -46.1 0.0 0.0 0.493 A:Q07820:0.493
 CD
CD
HOH
 7.009
9.719
5.494
 N
N
O
 CD
CD
O
GLY D:20 D:67 36.0 0.48 H -63.3 -47.1 NA NA NA
3pl7 2 Q07812 100.0 2e-17 X-RAY
 2010-12-29 GLY B:20 C:67 35.0 0.467 H -60.9 -42.2 0.0 0.0 0.467 A:Q07817:0.467
 HOH
 4.871
 O
 O
4bd6 2 Q07812 100.0 2e-17 X-RAY
 2013-02-13 GLY B:20 C:67 29.0 0.387 H -58.7 -51.6 0.0 0.0 0.387 A:Q07812:0.387
 HOH
 7.576
 O
 O
2xa0 2 Q07813 96.67 2e-13 X-RAY
 2010-11-24 GLY C:16 C:67 37.0 0.493 H -53.6 -43.6 0.0 0.0 0.493 A:P10415:0.493
 HOH
 8.444
 O
 O
GLY D:16 D:67 36.0 0.48 H -58.6 -44.0 NA NA NA
4uf2 2 Q07812 100.0 6e-13 X-RAY
 2015-08-05 GLY B:18 B:19 25.0 0.333 H -63.9 -30.9 0.0 0.0 0.333 A:Q08FF8:0.333
5ua5 2 F1RIQ4 100.0 6e-13 X-RAY
 2017-01-04 GLY B:18 B:42 37.0 0.493 H -55.6 -37.7 0.0 0.0 0.493 A:D0Q0E8:0.493
6trr 2 Q07812 100.0 6e-13 X-RAY
 2020-06-03 GLY B:18 B:165 26.0 0.347 H -59.4 -47.4 0.0 0.0 0.347 A:Q9DHU6:0.347
 HOH
 5.589
 O
 O
6xy6 2 Q07812 100.0 6e-13 X-RAY
 2020-07-29 GLY B:18 B:67 30.0 0.4 H -69.9 -40.8 1.0 0.013 0.387 A:A0A3F2YKH3:0.387
GLY D:18 D:67 27.0 0.36 H -71.0 -39.1 NA NA NA
GLY F:18 F:67 30.0 0.4 H -69.1 -39.3 NA NA NA
GLY H:18 H:67 28.0 0.373 H -70.6 -40.2 NA NA NA
GLY J:18 J:67 28.0 0.373 H -69.8 -41.0 NA NA NA
GLY L:18 L:67 29.0 0.387 H -70.1 -39.6 NA NA NA
GLY N:18 N:67 29.0 0.387 H -68.4 -39.9 NA NA NA
GLY P:18 P:67 32.0 0.427 H -69.7 -41.3 NA NA NA
7adt 2 Q07812 100.0 6e-13 X-RAY
 2021-10-06 GLY B:18 U:67 30.0 0.4 H -57.1 -42.0 0.0 0.0 0.4 A:A0A0R8HV90:0.4
 MG
MG
HOH
 7.341
6.424
5.213
 H
N
O
 MG
MG
O
GLY D:18 C:67 35.0 0.467 H -63.7 -45.7 0.0 0.0 0.467 C:A0A0R8HV90:0.467
 MG
MG
MG
HOH
 9.944
7.953
7.677
7.629
 HA3
C
H
HA3
 MG
MG
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q07812-f1 1 Q07812 100.0 1e-140 GLY A:67 A:67 0.0 0.0 H -63.7 -31.2