Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55253530 . C A CCDS33107.1:NM_015868.2:c.175Ctt>Att_NP_056952.2:p.59L>I Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 LEU A:38 A:38 46.0 0.271 E -122.8 133.9 46.0 0.271 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 LEU D:39 D:38 42.0 0.247 E -114.5 126.3 42.0 0.247 0.0 HOH
 4.941
 CD1
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 LEU D:38 D:38 53.0 0.312 E -119.4 123.5 53.0 0.312 0.0
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 LEU A:39 G:38 22.0 0.129 E -121.9 136.8 22.0 0.129 0.0
LEU B:39 I:38 22.0 0.129 E -121.7 136.5 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 LEU D:38 D:38 17.0 0.1 E -151.9 147.1 17.0 0.1 0.0
LEU H:38 H:38 16.0 0.094 E -151.5 147.5 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 LEU A:38 A:38 12.0 0.071 E -116.8 121.1 12.0 0.071 0.0 HOH
 7.861
 C
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 LEU D:38 D:38 18.0 0.106 E -119.7 133.6 18.0 0.106 0.0
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 LEU D:38 D:38 11.0 0.065 E -116.5 124.8 11.0 0.065 0.0 HOH
 6.699
 CD1
 O
LEU E:38 E:38 15.0 0.088 E -116.1 124.0 1.0 0.006 0.082 D:P43627:0.082
 HOH
 7.809
 O
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 LEU A:35 A:38 38.0 0.224 E -131.8 132.5 38.0 0.224 0.0 HOH
 3.949
 CD1
 O
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 LEU A:35 A:38 6.0 0.035 E -137.6 121.4 6.0 0.035 0.0 HOH
 5.533
 CD2
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 LEU A:39 A:38 43.0 0.253 E -113.5 118.4 43.0 0.253 0.0 HOH
 3.959
 CD2
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 LEU A:33 A:38 21.0 0.124 E -115.4 117.7 21.0 0.124 0.0 HOH
 7.055
 CD2
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 PHE D:133 G:133 9.0 0.043 E -128.1 135.2 9.0 0.043 0.0 NAG
HOH
 7.060
3.148
 CE2
CZ
 C8
O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 PHE C:133 G:133 12.0 0.057 E -119.0 130.7 12.0 0.057 0.0 NAG
HOH
 7.102
5.754
 CE1
CE2
 C8
O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 PHE D:133 G:133 12.0 0.057 E -123.0 130.7 12.0 0.057 0.0 NAG
HOH
 6.938
4.516
 CE2
CZ
 O7
O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 PHE G:133 G:133 5.0 0.024 E -122.9 125.7 5.0 0.024 0.0 NAG
HOH
 6.629
5.911
 CE1
CE2
 C8
O
PHE H:133 H:133 6.0 0.029 E -123.1 120.6 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 PHE D:133 G:133 10.0 0.048 E -124.3 127.2 10.0 0.048 0.0 NAG
HOH
 7.235
6.694
 CE1
C
 C8
O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 PHE D:150 G:133 9.0 0.043 E -128.3 134.6 9.0 0.043 0.0 NAG
HOH
 6.817
3.271
 CE1
CZ
 C8
O
PHE H:150 H:133 7.0 0.033 E -131.6 137.4 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 PHE D:133 G:133 11.0 0.052 E -123.0 121.0 11.0 0.052 0.0 NAG
HOH
 6.787
7.599
 CE1
CD1
 C8
O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 PHE D:142 G:133 7.0 0.033 E -128.6 135.1 7.0 0.033 0.0 NAG
HOH
 6.849
2.999
 CE1
CZ
 C8
O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 PHE D:128 G:133 5.0 0.024 E -129.1 125.9 5.0 0.024 0.0 NAG
HOH
 7.017
6.703
 CE2
CD2
 C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 LEU A:59 A:59 27.0 0.159 E -115.3 128.0
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 LEU A:59 A:59 40.0 0.235 E -115.6 127.5
af-p43627-f1 1 P43627 95.0 0.0 LEU A:59 A:59 38.0 0.224 E -115.0 128.6
af-p43626-f1 1 P43626 91.76 0.0 LEU A:59 A:59 33.0 0.194 E -115.6 123.5
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 LEU A:59 A:59 30.0 0.176 E -117.6 120.6
af-p43631-f1 1 P43631 95.72 0.0 LEU A:59 A:59 37.0 0.218 E -114.3 126.5
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 LEU A:59 A:59 32.0 0.188 E -116.7 123.4
af-q14954-f1 1 Q14954 90.79 0.0 LEU A:59 A:59 30.0 0.176 E -115.5 124.5
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 LEU A:59 A:59 31.0 0.182 E -116.3 125.3
af-q14953-f1 1 Q14953 89.8 0.0 LEU A:59 A:59 30.0 0.176 E -117.4 125.7
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 LEU A:52 A:52 30.0 0.176 E -116.5 124.7
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 LEU A:59 A:59 31.0 0.182 E -117.1 126.4
af-q14952-f1 1 Q14952 89.14 0.0 LEU A:59 A:59 24.0 0.141 E -118.6 124.3
af-p43632-f1 1 P43632 88.16 0.0 LEU A:59 A:59 38.0 0.224 E -115.2 126.8
af-a0a1w2pqm1-f1 1 A0A1W2PQM1 85.53 0.0 LEU A:59 A:59 30.0 0.176 E -116.4 129.0
af-p43629-f1 1 P43629 85.53 0.0 PHE A:154 A:154 7.0 0.033 E -123.1 127.2
af-p43630-f1 1 P43630 84.91 0.0 PHE A:154 A:154 4.0 0.019 E -124.2 127.7
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 LEU A:153 A:153 21.0 0.124 E -117.5 130.1
af-q14943-f1 1 Q14943 82.54 9e-149 PHE A:154 A:154 5.0 0.024 E -122.1 131.5
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 LEU A:59 A:59 28.0 0.165 E -117.3 127.1
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 LEU A:36 A:36 35.0 0.206 E -117.7 130.2
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 LEU A:36 A:36 41.0 0.241 E -115.8 129.4
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 LEU A:36 A:36 34.0 0.2 E -116.4 131.3
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 LEU A:36 A:36 36.0 0.212 E -115.7 127.4
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 LEU A:36 A:36 31.0 0.182 E -118.3 125.5
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 LEU A:154 A:154 4.0 0.024 E -118.7 132.4
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 LEU A:154 A:154 3.0 0.018 E -118.9 131.4