Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55253557 . G A CCDS33107.1:NM_015868.2:c.202Gac>Aac_NP_056952.2:p.68D>N Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 ASP A:47 A:47 70.0 0.467 E -139.8 164.3 70.0 0.467 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 ASP D:48 D:47 74.0 0.493 E -173.3 153.6 74.0 0.493 0.0 HOH
 2.972
 OD2
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 ASP D:47 D:47 74.0 0.493 E -160.1 163.2 74.0 0.493 0.0
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 ASP A:48 G:47 71.0 0.473 E -166.7 148.1 71.0 0.473 0.0
ASP B:48 I:47 70.0 0.467 E -166.8 148.4 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 ASP D:47 D:47 76.0 0.507 E -159.2 167.6 76.0 0.507 0.0
ASP H:47 H:47 72.0 0.48 E -158.4 166.6 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 ASP A:47 A:47 102.0 0.68 E -167.2 173.3 102.0 0.68 0.0 HOH
 4.226
 CB
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 ASP D:47 D:47 77.0 0.513 E -152.4 163.8 77.0 0.513 0.0 HOH
 8.235
 N
 O
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 ASP D:47 D:47 74.0 0.493 E -172.1 161.3 74.0 0.493 0.0 HOH
 3.169
 OD2
 O
ASP E:47 E:47 81.0 0.54 E -173.4 167.1 80.0 0.533 0.007 D:P43627:0.007
 HOH
 3.347
 OD1
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 ASP A:44 A:47 55.0 0.367 -148.6 157.2 55.0 0.367 0.0
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 ASP A:44 A:47 100.0 0.667 -163.6 178.2 100.0 0.667 0.0 HOH
 4.295
 OD1
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 ASP A:48 A:47 72.0 0.48 E -162.6 155.2 72.0 0.48 0.0 HOH
 2.876
 OD1
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 ASN A:42 A:47 60.0 0.375 E -165.0 149.7 60.0 0.375 0.0 HOH
 3.020
 ND2
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 ASP D:142 G:142 135.0 0.9 -71.3 136.2 122.0 0.813 0.087 A:P18465:0.087
 HOH
 2.960
 OD2
 O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 ASP C:142 G:142 147.0 0.98 -91.4 130.6 127.0 0.847 0.133 A:P18465:0.133
 HOH
 2.659
 OD1
 O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 ASP D:142 G:142 148.0 0.987 -98.1 123.5 147.0 0.98 0.007 A:I3ZN84:0.007
 NAG
HOH
 8.195
2.384
 OD1
O
 O7
O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 ASP G:142 G:142 84.0 0.56 -62.0 139.7 84.0 0.56 0.0 NAG
HOH
 6.370
2.154
 OD2
OD2
 C8
O
ASP H:142 H:142 78.0 0.52 -68.1 137.7 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 ASP D:142 G:142 133.0 0.887 -99.3 135.7 133.0 0.887 0.0 NAG
HOH
 7.753
2.348
 OD1
O
 C8
O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 ASP D:159 G:142 85.0 0.567 -67.5 135.9 85.0 0.567 0.0 NAG
HOH
 5.407
2.662
 OD2
OD1
 C8
O
ASP H:159 H:142 84.0 0.56 -61.9 134.4 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 ASP D:142 G:142 121.0 0.807 -102.5 139.4 121.0 0.807 0.0 NAG
HOH
 7.477
2.305
 OD2
OD2
 C8
O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 ASP D:151 G:142 100.0 0.667 -70.2 136.4 100.0 0.667 0.0 NAG
HOH
 8.009
2.087
 OD1
OD2
 C8
O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 ASP D:137 G:142 97.0 0.647 -63.8 146.5 97.0 0.647 0.0 NAG
HOH
 4.794
2.756
 OD2
OD1
 C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 ASP A:68 A:68 73.0 0.487 E -148.0 153.6
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 ASP A:68 A:68 63.0 0.42 E -149.6 153.6
af-p43627-f1 1 P43627 95.0 0.0 ASP A:68 A:68 74.0 0.493 E -148.8 155.5
af-p43626-f1 1 P43626 91.76 0.0 ASP A:68 A:68 48.0 0.32 E -141.1 168.0
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 ASP A:68 A:68 76.0 0.507 E -148.3 156.2
af-p43631-f1 1 P43631 95.72 0.0 ASP A:68 A:68 51.0 0.34 E -140.6 169.4
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 ASP A:68 A:68 80.0 0.533 E -149.1 156.9
af-q14954-f1 1 Q14954 90.79 0.0 ASP A:68 A:68 51.0 0.34 E -137.0 161.2
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 HIS A:68 A:68 95.0 0.487 E -147.2 144.3
af-q14953-f1 1 Q14953 89.8 0.0 HIS A:68 A:68 92.0 0.472 E -147.2 143.5
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 ASP A:61 A:61 48.0 0.32 E -140.5 168.4
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 HIS A:68 A:68 92.0 0.472 E -146.8 142.5
af-q14952-f1 1 Q14952 89.14 0.0 ASP A:68 A:68 70.0 0.467 E -142.5 154.9
af-p43632-f1 1 P43632 88.16 0.0 ASN A:68 A:68 69.0 0.431 E -146.5 151.6
af-a0a1w2pqm1-f1 1 A0A1W2PQM1 85.53 0.0 ASN A:68 A:68 80.0 0.5 E -144.0 153.6
af-p43629-f1 1 P43629 85.53 0.0 ASP A:163 A:163 133.0 0.887 -54.2 135.2
af-p43630-f1 1 P43630 84.91 0.0 ASP A:163 A:163 104.0 0.693 -64.9 142.0
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 HIS A:162 A:162 96.0 0.492 E -146.2 143.4
af-q14943-f1 1 Q14943 82.54 9e-149 ASP A:163 A:163 116.0 0.773 -57.2 137.1
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 HIS A:68 A:68 92.0 0.472 E -146.6 142.9
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 ASP A:45 A:45 68.0 0.453 E -146.7 156.0
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 ASP A:45 A:45 68.0 0.453 E -147.4 153.5
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 ASP A:45 A:45 70.0 0.467 E -146.1 157.2
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 ASP A:45 A:45 52.0 0.347 E -138.6 169.6
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 ASP A:45 A:45 74.0 0.493 E -146.2 154.8
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 ASP A:163 A:163 51.0 0.34 E -138.4 162.0
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 ASP A:163 A:163 54.0 0.36 E -133.0 167.1