Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55253629 . C A CCDS33107.1:NM_015868.2:c.274Caa>Aaa_NP_056952.2:p.92Q>K Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 GLN A:71 A:71 83.0 0.461 T -58.6 -33.6 83.0 0.461 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 GLN D:72 D:71 94.0 0.522 G -60.3 -46.9 18.0 0.1 0.422 A:P30504:0.228
C:None:0.256
 HOH
 2.645
 OE1
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 GLN D:71 D:71 87.0 0.483 G -66.4 -37.0 17.0 0.094 0.389 A:P10321:0.222
C:None:0.256
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 GLN A:72 G:71 82.0 0.456 T -64.1 -16.2 26.0 0.144 0.312 C:P13746:0.2
E:Q76ZQ3:0.144
 HOH
 5.460
 O
 O
GLN B:72 I:71 82.0 0.456 T -63.9 -17.2 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 GLN D:71 D:71 90.0 0.5 G -57.4 -30.8 6.0 0.033 0.467 A:P10321:0.272
C:None:0.306
GLN H:71 H:71 97.0 0.539 G -56.0 -30.5 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 GLN A:71 A:71 85.0 0.472 G -52.2 -42.3 85.0 0.472 0.0 HOH
 5.119
 NE2
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 GLN D:71 D:71 81.0 0.45 G -61.3 -30.5 22.0 0.122 0.328 C:None:0.256
A:F6IQA6:0.172
 HOH
 3.154
 O
 O
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 GLN D:71 D:71 92.0 0.511 G 1.5 -72.6 13.0 0.072 0.439 C:P52292:0.328
A:495038:0.217
 HOH
 2.761
 CG
 O
GLN E:71 E:71 93.0 0.517 G -2.8 -72.9 93.0 0.517 0.0 HOH
 7.681
 OE1
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 GLN A:68 A:71 86.0 0.478 T -43.2 -41.0 86.0 0.478 0.0 HOH
 6.508
 OE1
 O
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 GLN A:68 A:71 80.0 0.444 G -23.1 -80.4 80.0 0.444 0.0
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 GLN A:72 A:71 90.0 0.5 G -58.0 -25.0 90.0 0.5 0.0 HOH
 2.533
 O
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 PRO A:66 A:71 62.0 0.428 T -47.6 -18.3 62.0 0.428 0.0 HOH
 4.167
 CB
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 LEU D:166 G:166 86.0 0.506 G -53.4 -41.1 30.0 0.176 0.33 A:P18465:0.276
C:None:0.094
 HOH
 2.650
 O
 O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 LEU C:166 G:166 79.0 0.465 G -57.9 -35.7 14.0 0.082 0.383 D:None:0.135
A:P18465:0.3
 HOH
 3.389
 CD1
 O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 LEU D:166 G:166 81.0 0.476 G -58.1 -34.6 16.0 0.094 0.382 C:None:0.159
A:I3ZN84:0.294
 HOH
 2.788
 O
 O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 LEU G:166 G:166 78.0 0.459 G -64.5 -39.9 33.0 0.194 0.265 C:None:0.059
A:A0A411J078:0.224
 HOH
 3.905
 CD1
 O
LEU H:166 H:166 89.0 0.524 G -57.3 -39.2 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 LEU D:166 G:166 86.0 0.506 G -60.5 -33.0 24.0 0.141 0.365 A:P18465:0.253
C:P01834:0.171
 HOH
 3.579
 CD1
 O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 LEU D:183 G:166 85.0 0.5 G -53.3 -40.7 21.0 0.124 0.376 A:P18465:0.282
C:P01834:0.159
 HOH
 2.716
 O
 O
LEU H:183 H:166 84.0 0.494 G -55.5 -40.9 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 LEU D:166 G:166 87.0 0.512 G -59.9 -32.8 17.0 0.1 0.412 C:P01834:0.182
A:P18465:0.306
 HOH
 2.935
 N
 O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 LEU D:175 G:166 88.0 0.518 G -52.9 -40.8 15.0 0.088 0.43 A:P18465:0.318
C:None:0.165
 HOH
 2.724
 O
 O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 LEU D:161 G:166 85.0 0.5 G -56.8 -35.2 85.0 0.5 0.0 HOH
 3.714
 CD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 GLN A:92 A:92 84.0 0.467 G -56.5 -30.3
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 GLN A:92 A:92 83.0 0.461 T -58.3 -28.6
af-p43627-f1 1 P43627 95.0 0.0 GLN A:92 A:92 83.0 0.461 T -57.8 -28.3
af-p43626-f1 1 P43626 91.76 0.0 GLN A:92 A:92 91.0 0.506 G -57.5 -37.9
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 GLN A:92 A:92 89.0 0.494 G -58.1 -37.8
af-p43631-f1 1 P43631 95.72 0.0 GLN A:92 A:92 87.0 0.483 G -56.1 -29.5
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 GLN A:92 A:92 83.0 0.461 G -58.4 -39.2
af-q14954-f1 1 Q14954 90.79 0.0 GLN A:92 A:92 91.0 0.506 G -56.8 -39.7
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 GLN A:92 A:92 97.0 0.539 G -58.3 -31.5
af-q14953-f1 1 Q14953 89.8 0.0 GLN A:92 A:92 97.0 0.539 G -57.1 -33.2
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 GLN A:85 A:85 90.0 0.5 G -55.9 -41.7
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 GLN A:92 A:92 95.0 0.528 G -57.3 -33.1
af-q14952-f1 1 Q14952 89.14 0.0 GLN A:92 A:92 95.0 0.528 G -52.7 -38.1
af-p43632-f1 1 P43632 88.16 0.0 PRO A:92 A:92 46.0 0.317 G -51.3 -36.5
af-a0a1w2pqm1-f1 1 A0A1W2PQM1 85.53 0.0 PRO A:92 A:92 49.0 0.338 G -51.2 -35.9
af-p43629-f1 1 P43629 85.53 0.0 LEU A:187 A:187 77.0 0.453 G -49.5 -44.9
af-p43630-f1 1 P43630 84.91 0.0 PRO A:187 A:187 60.0 0.414 G -51.1 -29.7
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 GLN A:186 A:186 100.0 0.556 G -58.1 -32.6
af-q14943-f1 1 Q14943 82.54 9e-149 ARG A:187 A:187 159.0 0.707 G -48.2 -45.9
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 GLN A:92 A:92 97.0 0.539 G -57.7 -33.0
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 GLN A:69 A:69 80.0 0.444 T -55.7 -29.6
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 GLN A:69 A:69 82.0 0.456 G -55.9 -31.8
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 GLU A:69 A:69 81.0 0.426 G -61.2 -28.3
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 GLN A:69 A:69 84.0 0.467 G -55.0 -38.4
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 GLN A:69 A:69 99.0 0.55 G -57.9 -34.3
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 GLN A:187 A:187 88.0 0.489 T -58.4 -28.5
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 GLN A:187 A:187 92.0 0.511 T -56.7 -29.2