Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55253634 . C A CCDS33107.1:NM_015868.2:c.279gaC>gaA_NP_056952.2:p.93D>E Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 ASP A:72 A:72 53.0 0.353 T -71.8 -10.9 53.0 0.353 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 ASP D:73 D:72 63.0 0.42 G -56.7 -3.5 25.0 0.167 0.253 A:P30504:0.253
 HOH
 4.479
 N
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 ASP D:72 D:72 66.0 0.44 G -70.0 -4.8 18.0 0.12 0.32 A:P10321:0.32
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 ASP A:73 G:72 71.0 0.473 T -81.6 -11.4 25.0 0.167 0.306 C:P13746:0.307
 HOH
 7.690
 N
 O
ASP B:73 I:72 69.0 0.46 T -80.4 -12.5 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 ASP D:72 D:72 73.0 0.487 G -84.3 0.5 22.0 0.147 0.34 A:P10321:0.34
ASP H:72 H:72 80.0 0.533 G -83.9 1.5 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 ASP A:72 A:72 58.0 0.387 G -63.0 -24.7 58.0 0.387 0.0 HOH
 6.317
 O
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 ASP D:72 D:72 78.0 0.52 G -72.5 -8.8 44.0 0.293 0.227 A:F6IQA6:0.227
 HOH
 2.807
 OD2
 O
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 ASP D:72 D:72 68.0 0.453 G -60.2 -43.2 12.0 0.08 0.373 A:495038:0.373
 HOH
 2.825
 OD2
 O
ASP E:72 E:72 74.0 0.493 G -51.6 -50.8 74.0 0.493 0.0 HOH
 6.980
 O
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 ASP A:69 A:72 72.0 0.48 T -66.2 -41.1 72.0 0.48 0.0 HOH
 9.375
 N
 O
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 ASP A:69 A:72 58.0 0.387 G -59.8 8.0 58.0 0.387 0.0 HOH
 8.100
 OD2
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 ASP A:73 A:72 53.0 0.353 G -68.8 -14.0 53.0 0.353 0.0 HOH
 2.878
 O
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 VAL A:67 A:72 73.0 0.471 T -94.6 -14.0 73.0 0.471 0.0 HOH
 2.485
 O
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 ALA D:167 G:167 67.0 0.583 G -63.0 -22.7 19.0 0.165 0.418 A:P18465:0.417
 HOH
 2.795
 N
 O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 ALA C:167 G:167 74.0 0.643 G -58.2 -26.5 14.0 0.122 0.521 A:P18465:0.522
 HOH
 3.609
 CB
 O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 ALA D:167 G:167 59.0 0.513 G -63.7 -19.4 10.0 0.087 0.426 A:I3ZN84:0.426
 HOH
 3.597
 CB
 O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 ALA G:167 G:167 75.0 0.652 G -59.9 -13.9 35.0 0.304 0.348 A:A0A411J078:0.348
 HOH
 3.701
 O
 O
ALA H:167 H:167 74.0 0.643 G -65.0 -14.3 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 ALA D:167 G:167 74.0 0.643 G -63.8 -21.0 15.0 0.13 0.513 A:P18465:0.513
 HOH
 6.772
 N
 O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 ALA D:184 G:167 67.0 0.583 G -62.6 -22.5 26.0 0.226 0.357 A:P18465:0.357
 HOH
 2.777
 O
 O
ALA H:184 H:167 69.0 0.6 G -61.4 -19.7 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 ALA D:167 G:167 76.0 0.661 G -63.3 -18.2 10.0 0.087 0.574 A:P18465:0.574
 HOH
 3.690
 O
 O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 ALA D:176 G:167 69.0 0.6 G -63.1 -23.4 24.0 0.209 0.391 A:P18465:0.391
 HOH
 3.156
 N
 O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 ALA D:162 G:167 76.0 0.661 G -62.2 -24.0 76.0 0.661 0.0 HOH
 5.726
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 ASP A:93 A:93 54.0 0.36 G -76.1 -17.3
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 ASP A:93 A:93 53.0 0.353 T -76.6 -18.7
af-p43627-f1 1 P43627 95.0 0.0 ASP A:93 A:93 50.0 0.333 T -78.7 -18.9
af-p43626-f1 1 P43626 91.76 0.0 ASP A:93 A:93 65.0 0.433 G -70.0 -13.9
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 ASP A:93 A:93 61.0 0.407 G -69.5 -15.2
af-p43631-f1 1 P43631 95.72 0.0 ASP A:93 A:93 51.0 0.34 G -77.9 -17.3
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 ASP A:93 A:93 58.0 0.387 G -68.8 -16.5
af-q14954-f1 1 Q14954 90.79 0.0 ASP A:93 A:93 58.0 0.387 G -70.2 -14.0
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 ASP A:93 A:93 65.0 0.433 G -74.9 -14.5
af-q14953-f1 1 Q14953 89.8 0.0 ASP A:93 A:93 65.0 0.433 G -73.6 -15.3
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 ASP A:86 A:86 54.0 0.36 G -71.1 -12.1
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 ASP A:93 A:93 65.0 0.433 G -74.4 -14.5
af-q14952-f1 1 Q14952 89.14 0.0 ASP A:93 A:93 50.0 0.333 G -72.4 -12.7
af-p43632-f1 1 P43632 88.16 0.0 VAL A:93 A:93 51.0 0.329 G -68.3 -14.1
af-a0a1w2pqm1-f1 1 A0A1W2PQM1 85.53 0.0 VAL A:93 A:93 48.0 0.31 G -66.2 -18.1
af-p43629-f1 1 P43629 85.53 0.0 ALA A:188 A:188 72.0 0.626 G -64.5 -16.5
af-p43630-f1 1 P43630 84.91 0.0 VAL A:188 A:188 94.0 0.606 G -64.8 -20.8
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 ASP A:187 A:187 66.0 0.44 G -74.2 -14.8
af-q14943-f1 1 Q14943 82.54 9e-149 ALA A:188 A:188 67.0 0.583 G -67.8 -6.0
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 ASP A:93 A:93 65.0 0.433 G -74.4 -15.3
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 ASP A:70 A:70 53.0 0.353 T -77.7 -18.2
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 ASP A:70 A:70 51.0 0.34 G -78.1 -15.5
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 ASP A:70 A:70 52.0 0.347 G -74.7 -15.8
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 ASP A:70 A:70 61.0 0.407 G -69.9 -14.5
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 ASP A:70 A:70 64.0 0.427 G -72.7 -16.3
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 ASP A:188 A:188 64.0 0.427 T -76.8 -19.0
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 ASP A:188 A:188 61.0 0.407 T -77.6 -17.9