Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55255327 . G A CCDS33107.1:NM_015868.2:c.455cGg>cAg_NP_056952.2:p.152R>Q Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 ARG A:131 A:131 195.0 0.867 S -82.4 -20.3 195.0 0.867 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 ARG D:132 D:131 182.0 0.809 S -74.1 -21.7 182.0 0.809 0.0 HOH
 9.062
 O
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 ARG D:131 D:131 195.0 0.867 S -86.4 -8.0 195.0 0.867 0.0
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 ARG A:132 G:131 178.0 0.791 S -71.0 -28.3 178.0 0.791 0.0 HOH
 3.007
 O
 O
ARG B:132 I:131 179.0 0.796 S -71.1 -28.5 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 ARG D:131 D:131 189.0 0.84 S -66.2 -27.1 189.0 0.84 0.0
ARG H:131 H:131 204.0 0.907 S -66.2 -26.8 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 ARG A:131 A:131 232.0 1.0 E -77.5 -15.6 232.0 1.0 0.0 HOH
 2.799
 N
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 ARG D:131 D:131 214.0 0.951 S -98.7 -4.1 210.0 0.933 0.018 A:F6IQA6:0.018
 HOH
 4.921
 O
 O
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 ARG D:131 D:131 188.0 0.836 S -74.4 -28.5 188.0 0.836 0.0 HOH
 3.537
 N
 O
ARG E:131 E:131 216.0 0.96 S -67.4 -41.7 216.0 0.96 0.0 HOH
 4.400
 CA
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 ARG A:128 A:131 203.0 0.902 S -87.7 -15.1 203.0 0.902 0.0 HOH
 8.526
 CG
 O
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 ARG A:128 A:131 218.0 0.969 S -74.5 -21.2 218.0 0.969 0.0 HOH
 4.415
 N
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 ARG A:132 A:131 178.0 0.791 S -88.8 -14.9 178.0 0.791 0.0 HOH
 2.723
 O
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 ARG A:126 A:131 167.0 0.742 S -95.6 -13.5 167.0 0.742 0.0 HOH
 7.415
 NH1
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 ARG D:226 G:226 217.0 0.964 S -80.4 -18.4 217.0 0.964 0.0 NAG
HOH
 4.593
2.241
 NH2
NH2
 C8
O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 ARG C:226 G:226 181.0 0.804 S -84.1 -18.0 181.0 0.804 0.0 NAG
HOH
 3.445
2.553
 NH2
O
 C8
O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 ARG D:226 G:226 175.0 0.778 S -83.8 -13.6 175.0 0.778 0.0 NAG
HOH
 4.750
2.454
 NH1
NH2
 C8
O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 ARG G:226 G:226 132.0 0.587 S -81.9 -17.9 132.0 0.587 0.0 NAG
HOH
 5.421
3.749
 NH2
N
 N2
O
ARG H:226 H:226 162.0 0.72 S -73.6 -7.1 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 ARG D:226 G:226 176.0 0.782 S -74.1 -23.6 176.0 0.782 0.0 NAG
HOH
 5.276
4.662
 NE
O
 C8
O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 ARG D:243 G:226 217.0 0.964 S -80.4 -18.0 217.0 0.964 0.0 NAG
HOH
 4.767
2.728
 NH2
O
 C8
O
ARG H:243 H:226 218.0 0.969 S -82.2 -15.3 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 ARG D:226 G:226 205.0 0.911 S -76.2 -27.4 190.0 0.844 0.067 A:P18465:0.067
 NAG
HOH
 7.335
2.239
 N
NH2
 C8
O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 ARG D:235 G:226 218.0 0.969 S -79.2 -19.6 218.0 0.969 0.0 NAG
HOH
 6.171
2.894
 NE
O
 C8
O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 ARG D:221 G:226 152.0 0.676 S -89.9 -18.8 152.0 0.676 0.0 NAG
HOH
 5.268
3.687
 NE
N
 C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 ARG A:152 A:152 208.0 0.924 S -77.8 -22.4
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 ARG A:152 A:152 200.0 0.889 S -78.6 -23.1
af-p43627-f1 1 P43627 95.0 0.0 ARG A:152 A:152 206.0 0.916 S -78.6 -21.3
af-p43626-f1 1 P43626 91.76 0.0 ARG A:152 A:152 220.0 0.978 S -78.4 -21.2
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 ARG A:152 A:152 216.0 0.96 S -80.6 -21.2
af-p43631-f1 1 P43631 95.72 0.0 ARG A:152 A:152 202.0 0.898 S -77.7 -22.2
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 ARG A:152 A:152 210.0 0.933 S -73.7 -25.9
af-q14954-f1 1 Q14954 90.79 0.0 ARG A:152 A:152 204.0 0.907 S -77.7 -20.1
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 ARG A:152 A:152 207.0 0.92 S -78.5 -20.2
af-q14953-f1 1 Q14953 89.8 0.0 ARG A:152 A:152 179.0 0.796 S -77.9 -19.2
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 ARG A:145 A:145 211.0 0.938 S -73.7 -23.1
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 ARG A:152 A:152 204.0 0.907 S -79.8 -19.2
af-q14952-f1 1 Q14952 89.14 0.0 TRP A:152 A:152 194.0 0.761 S -75.6 -22.6
af-p43632-f1 1 P43632 88.16 0.0 ARG A:152 A:152 218.0 0.969 S -77.8 -22.5
af-p43629-f1 1 P43629 85.53 0.0 ARG A:247 A:247 211.0 0.938 S -78.2 -24.4
af-p43630-f1 1 P43630 84.91 0.0 TRP A:247 A:247 182.0 0.714 S -74.7 -24.7
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 ARG A:246 A:246 205.0 0.911 S -76.6 -20.5
af-q14943-f1 1 Q14943 82.54 9e-149 ARG A:247 A:247 211.0 0.938 S -80.2 -22.5
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 ARG A:152 A:152 206.0 0.916 S -79.0 -20.8
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 ARG A:129 A:129 204.0 0.907 S -77.9 -21.6
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 ARG A:129 A:129 209.0 0.929 S -77.2 -23.6
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 ARG A:128 A:128 202.0 0.898 S -77.0 -20.0
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 ARG A:129 A:129 202.0 0.898 S -78.1 -21.3
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 ARG A:129 A:129 209.0 0.929 S -78.1 -21.2
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 ARG A:247 A:247 215.0 0.956 S -79.4 -20.1
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 ARG A:247 A:247 215.0 0.956 S -79.9 -20.5