Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55255335 . T A CCDS33107.1:NM_015868.2:c.463Tat>Aat_NP_056952.2:p.155Y>N Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 TYR A:134 A:134 2.0 0.009 -62.8 134.6 2.0 0.009 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 TYR D:135 D:134 0.0 0.0 -72.1 143.1 0.0 0.0 0.0 HOH
 3.190
 O
 O
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 TYR D:134 D:134 3.0 0.013 -57.6 157.4 1.0 0.004 0.009 A:P10321:0.009
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 TYR A:135 G:134 2.0 0.009 -63.3 145.8 2.0 0.009 0.0 HOH
 5.685
 CE2
 O
TYR B:135 I:134 4.0 0.017 -63.9 147.0 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 TYR D:134 D:134 2.0 0.009 -76.9 140.0 1.0 0.004 0.005 A:P10321:0.004
TYR H:134 H:134 3.0 0.013 -76.4 140.0 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 TYR A:134 A:134 2.0 0.009 E -127.8 148.0 2.0 0.009 0.0 HOH
 3.312
 OH
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 TYR D:134 D:134 1.0 0.004 -57.3 144.9 0.0 0.0 0.004 A:F6IQA6:0.004
 HOH
 3.292
 O
 O
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 TYR D:134 D:134 1.0 0.004 -55.1 146.4 0.0 0.0 0.004 A:495038:0.004
 HOH
 6.063
 CE2
 O
TYR E:134 E:134 0.0 0.0 -54.7 152.5 0.0 0.0 0.0 HOH
 6.672
 CD1
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 TYR A:131 A:134 4.0 0.017 -60.7 130.3 4.0 0.017 0.0
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 TYR A:131 A:134 1.0 0.004 -80.8 97.8 1.0 0.004 0.0 HOH
 6.051
 CE2
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 TYR A:135 A:134 3.0 0.013 -56.3 147.2 3.0 0.013 0.0 HOH
 3.183
 CD2
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 TYR A:129 A:134 3.0 0.013 -59.7 142.7 3.0 0.013 0.0 HOH
 4.729
 C
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 TYR D:229 G:229 2.0 0.009 -61.8 145.5 1.0 0.004 0.005 A:P18465:0.004
 HOH
 3.206
 O
 O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 TYR C:229 G:229 4.0 0.017 -74.5 148.1 2.0 0.009 0.008 A:P18465:0.009
 HOH
 5.222
 CE2
 O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 TYR D:229 G:229 2.0 0.009 -67.3 148.6 1.0 0.004 0.005 A:I3ZN84:0.004
 HOH
 3.218
 O
 O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 TYR G:229 G:229 2.0 0.009 -67.3 145.4 1.0 0.004 0.005 A:A0A411J078:0.004
 HOH
 5.034
 CE2
 O
TYR H:229 H:229 5.0 0.022 -66.4 151.8 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 TYR D:229 G:229 2.0 0.009 -68.5 130.7 1.0 0.004 0.005 A:P18465:0.004
 HOH
 5.411
 N
 O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 TYR D:246 G:229 2.0 0.009 -61.4 145.0 1.0 0.004 0.005 A:P18465:0.004
 HOH
 3.063
 O
 O
TYR H:246 H:229 1.0 0.004 -59.3 147.0 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 TYR D:229 G:229 2.0 0.009 -68.5 144.9 1.0 0.004 0.005 A:P18465:0.004
 HOH
 5.036
 CE2
 O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 TYR D:238 G:229 2.0 0.009 -61.8 145.6 1.0 0.004 0.005 A:P18465:0.004
 HOH
 3.007
 O
 O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 TYR D:224 G:229 3.0 0.013 -63.4 140.6 3.0 0.013 0.0 HOH
 5.023
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 TYR A:155 A:155 3.0 0.013 -63.3 132.0
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 TYR A:155 A:155 3.0 0.013 -64.0 132.2
af-p43627-f1 1 P43627 95.0 0.0 TYR A:155 A:155 2.0 0.009 -63.9 132.1
af-p43626-f1 1 P43626 91.76 0.0 TYR A:155 A:155 1.0 0.004 -62.6 135.1
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 TYR A:155 A:155 2.0 0.009 -64.1 133.8
af-p43631-f1 1 P43631 95.72 0.0 TYR A:155 A:155 2.0 0.009 -64.2 132.0
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 TYR A:155 A:155 3.0 0.013 -63.2 131.7
af-q14954-f1 1 Q14954 90.79 0.0 TYR A:155 A:155 2.0 0.009 -62.4 132.1
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 TYR A:155 A:155 2.0 0.009 -64.0 132.9
af-q14953-f1 1 Q14953 89.8 0.0 TYR A:155 A:155 2.0 0.009 -64.1 133.2
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 TYR A:148 A:148 2.0 0.009 -61.6 132.3
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 TYR A:155 A:155 2.0 0.009 -65.5 131.9
af-q14952-f1 1 Q14952 89.14 0.0 TYR A:155 A:155 2.0 0.009 -66.5 132.2
af-p43632-f1 1 P43632 88.16 0.0 TYR A:155 A:155 2.0 0.009 -59.7 138.0
af-p43629-f1 1 P43629 85.53 0.0 TYR A:250 A:250 3.0 0.013 -62.0 135.0
af-p43630-f1 1 P43630 84.91 0.0 TYR A:250 A:250 2.0 0.009 -62.2 135.6
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 TYR A:249 A:249 3.0 0.013 -65.7 133.4
af-q14943-f1 1 Q14943 82.54 9e-149 TYR A:250 A:250 2.0 0.009 -62.5 137.2
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 TYR A:155 A:155 2.0 0.009 -63.9 132.5
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 TYR A:132 A:132 2.0 0.009 -62.7 130.7
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 TYR A:132 A:132 3.0 0.013 -63.0 132.1
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 TYR A:131 A:131 1.0 0.004 -62.1 130.7
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 TYR A:132 A:132 2.0 0.009 -63.1 131.1
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 TYR A:132 A:132 2.0 0.009 -59.9 135.1
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 TYR A:250 A:250 1.0 0.004 -63.0 134.0
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 TYR A:250 A:250 1.0 0.004 -62.8 133.7