Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 55255422 . G A CCDS33107.1:NM_015868.2:c.550Gac>Aac_NP_056952.2:p.184D>N Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b6u 1 P43628 96.55 6e-167 X-RAY
 1999-01-27 ASP A:163 A:163 64.0 0.427 E -103.4 136.0 64.0 0.427 0.0
1im9 4 P43626 92.86 1e-153 X-RAY
 2001-05-30 ASP D:164 D:163 73.0 0.487 E -120.8 115.4 73.0 0.487 0.0
6pag 4 P43628 100.0 8e-151 X-RAY
 2020-12-16 ASP D:163 D:163 75.0 0.5 -148.6 134.6 75.0 0.5 0.0
4n8v 1 P43631 99.0 5e-147 X-RAY
 2014-02-05 ASP A:164 G:163 75.0 0.5 E -109.7 139.9 75.0 0.5 0.0 HOH
 2.770
 O
 O
ASP B:164 I:163 76.0 0.507 E -108.6 139.6 NA NA NA
6pa1 4 P43627 98.04 8e-147 X-RAY
 2020-12-16 ASP D:163 D:163 66.0 0.44 E -120.5 121.4 66.0 0.44 0.0
ASP H:163 H:163 69.0 0.46 E -120.5 121.5 NA NA NA
1m4k 1 P43631 99.0 1e-146 X-RAY
 2003-04-15 ASP A:163 A:163 78.0 0.52 E -102.9 136.1 78.0 0.52 0.0 HOH
 3.030
 N
 O
7duu 4 P43631 99.0 1e-146 X-RAY
 2022-02-02 ASP D:163 D:163 67.0 0.447 E -108.0 133.8 67.0 0.447 0.0
1efx 4 P43627 98.49 9e-144 X-RAY
 2000-06-14 ASP D:163 D:163 78.0 0.52 E -102.9 127.2 78.0 0.52 0.0
ASP E:163 E:163 73.0 0.487 E -104.1 122.1 73.0 0.487 0.0 HOH
 5.215
 OD2
 O
2dli 1 P43627 98.47 3e-141 X-RAY
 2000-01-13 ASP A:160 A:163 74.0 0.493 E -89.5 128.5 74.0 0.493 0.0 HOH
 3.258
 N
 O
2dl2 1 P43627 97.96 1e-140 X-RAY
 1999-03-30 ASP A:160 A:163 107.0 0.713 -66.4 116.2 107.0 0.713 0.0 HOH
 3.072
 O
 O
1nkr 1 P43626 92.5 4e-135 X-RAY
 1998-11-11 ASP A:164 A:163 81.0 0.54 E -111.5 112.5 81.0 0.54 0.0 HOH
 2.496
 O
 O
3h8n 1 P43632 89.23 3e-125 X-RAY
 2009-10-20 ASP A:158 A:163 80.0 0.533 E -117.5 112.2 80.0 0.533 0.0 HOH
 2.661
 OD2
 O
5t6z 4 P43629 84.16 1e-118 X-RAY
 2017-03-01 ASP D:258 G:258 72.0 0.48 E -112.2 112.5 72.0 0.48 0.0 NAG
HOH
 7.485
2.635
 OD1
N
 C6
O
5t70 3 P43629 84.16 1e-118 X-RAY
 2017-03-01 ASP C:258 G:258 74.0 0.493 E -108.7 114.7 74.0 0.493 0.0 NAG
HOH
 7.232
2.971
 OD1
N
 O4
O
6v3j 4 P43629 84.16 1e-118 X-RAY
 2020-05-20 ASP D:258 G:258 69.0 0.46 E -107.5 117.6 69.0 0.46 0.0 NAG
HOH
 7.789
2.876
 OD1
N
 O6
O
7k80 4 P43629 84.16 1e-118 X-RAY
 2020-12-09 ASP G:258 G:258 69.0 0.46 E -115.3 109.9 69.0 0.46 0.0 NAG
HOH
 8.112
6.968
 OD1
OD1
 O4
O
ASP H:258 H:258 69.0 0.46 E -115.4 116.3 NA NA NA
5b39 4 P43629 84.16 1e-118 X-RAY
 2016-03-30 ASP D:258 G:258 69.0 0.46 E -123.8 111.6 69.0 0.46 0.0 NAG
HOH
 6.704
8.125
 OD2
OD1
 O6
O
3vh8 4 P43629 84.16 2e-118 X-RAY
 2011-10-26 ASP D:275 G:258 72.0 0.48 E -112.1 112.5 72.0 0.48 0.0 NAG
HOH
 7.155
2.918
 OD1
N
 C6
O
ASP H:275 H:258 86.0 0.573 E -101.8 114.9 NA NA NA
5b38 4 P43629 83.17 9e-116 X-RAY
 2016-03-30 ASP D:258 G:258 58.0 0.387 E -118.2 107.3 58.0 0.387 0.0 NAG
HOH
 6.123
6.483
 OD1
C
 O4
O
3wuw 4 P43629 83.59 2e-113 X-RAY
 2014-05-28 ASP D:267 G:258 68.0 0.453 E -112.6 112.8 68.0 0.453 0.0 NAG
HOH
 6.223
5.202
 OD1
O
 O4
O
7k81 4 I6LEL9 82.74 5e-112 X-RAY
 2020-12-09 ASP D:253 G:258 70.0 0.467 E -111.2 116.7 70.0 0.467 0.0 NAG
HOH
 6.988
2.680
 OD1
N
 O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p43628-f1 1 P43628 100.0 0.0 ASP A:184 A:184 60.0 0.4 E -104.3 122.4
af-a0a0g2jnf4-f1 1 A0A0G2JNF4 97.35 0.0 ASP A:184 A:184 71.0 0.473 E -101.3 123.9
af-p43627-f1 1 P43627 95.0 0.0 ASP A:184 A:184 66.0 0.44 E -104.2 123.9
af-p43626-f1 1 P43626 91.76 0.0 ASP A:184 A:184 74.0 0.493 E -107.1 115.4
af-a0a191urj7-f1 1 A0A191URJ7 90.62 0.0 ASP A:184 A:184 66.0 0.44 E -103.1 112.7
af-p43631-f1 1 P43631 95.72 0.0 ASP A:184 A:184 67.0 0.447 E -102.6 126.1
af-a0a5k1vdz0-f1 1 A0A5K1VDZ0 86.18 0.0 ASN A:184 A:184 81.0 0.506 E -105.0 115.3
af-q14954-f1 1 Q14954 90.79 0.0 ASN A:184 A:184 75.0 0.469 E -103.3 116.3
af-a0a0g2jlq3-f1 1 A0A0G2JLQ3 89.8 0.0 ASP A:184 A:184 68.0 0.453 E -104.2 115.4
af-q14953-f1 1 Q14953 89.8 0.0 ASP A:184 A:184 78.0 0.52 E -103.3 116.4
af-a0a0g2jq47-f1 1 A0A0G2JQ47 90.91 0.0 ASN A:177 A:177 82.0 0.512 E -102.9 115.1
af-a0a0g2jng1-f1 1 A0A0G2JNG1 89.47 0.0 ASP A:184 A:184 72.0 0.48 E -107.7 113.5
af-q14952-f1 1 Q14952 89.14 0.0 ASP A:184 A:184 69.0 0.46 E -102.2 126.6
af-p43632-f1 1 P43632 88.16 0.0 ASP A:184 A:184 77.0 0.513 E -104.0 114.4
af-a0a1w2pqm1-f1 1 A0A1W2PQM1 85.53 0.0 ASP A:176 A:176 84.0 0.56 E -106.1 132.0
af-p43629-f1 1 P43629 85.53 0.0 ASP A:279 A:279 75.0 0.5 E -107.4 115.1
af-p43630-f1 1 P43630 84.91 0.0 ASP A:279 A:279 75.0 0.5 E -105.8 114.7
af-a0a0g2jlm5-f1 1 A0A0G2JLM5 90.04 0.0 ASP A:278 A:278 72.0 0.48 E -104.6 114.7
af-q14943-f1 1 Q14943 82.54 9e-149 ASP A:279 A:279 77.0 0.513 E -102.9 116.0
af-a0a376a8z9-f1 1 A0A376A8Z9 90.95 1e-147 ASP A:184 A:184 77.0 0.513 E -104.2 115.1
af-a0a2r8ycy7-f1 1 A0A2R8YCY7 98.49 8e-144 ASP A:161 A:161 77.0 0.513 E -102.9 126.8
af-a0a5f9z9y6-f1 1 A0A5F9Z9Y6 97.99 5e-143 ASP A:161 A:161 76.0 0.507 E -104.1 125.4
af-a0a1w2pqf6-f1 1 A0A1W2PQF6 97.99 2e-142 ASP A:160 A:160 78.0 0.52 E -102.4 126.2
af-a0a5f9zh88-f1 1 A0A5F9ZH88 94.97 9e-139 ASP A:161 A:161 78.0 0.52 E -101.5 126.0
af-a0a1w2prs3-f1 1 A0A1W2PRS3 88.94 2e-125 ASN A:161 A:161 69.0 0.431 E -105.8 123.7
af-a0a0g2jmm0-f1 1 A0A0G2JMM0 89.39 2e-123 ASN A:279 A:279 70.0 0.438 E -105.7 126.9
af-a0a0g2jn01-f1 1 A0A0G2JN01 88.89 6e-123 ASN A:279 A:279 73.0 0.456 E -105.5 126.7