Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6680176 . G A CCDS32883.1:NM_000064.2:c.4449taC>taT_NP_000055.2:p.1483Y>Y Homo sapiens complement component 3 (C3), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR B:812 B:1483 1.0 0.004 T -95.2 14.9 1.0 0.004 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 TYR B:811 B:1461 2.0 0.009 T -112.4 -6.1 2.0 0.009 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 TYR B:735 B:1461 105.0 0.457 T -87.6 14.6 92.0 0.4 0.057 A:P01024:0.057
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:735 B:1461 112.0 0.487 T -69.2 -26.3 92.0 0.4 0.087 A:P01024:0.087
 HOH
 3.346
 OH
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:735 B:1461 128.0 0.557 S -95.7 -11.8 110.0 0.478 0.079 A:P01024:0.078
TYR D:735 D:1461 127.0 0.552 S -95.7 -11.9 NA NA NA
TYR F:735 F:1461 124.0 0.539 S -95.5 -11.9 NA NA NA
TYR H:735 H:1461 128.0 0.557 S -95.5 -12.0 109.0 0.474 0.083 G:P01024:0.083
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 TYR B:735 B:1461 119.0 0.517 T -78.7 -0.5 117.0 0.509 0.008 A:P01024:0.009
TYR D:735 D:1461 125.0 0.543 T -79.6 -5.1 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 TYR B:735 B:1461 100.0 0.435 T -77.9 -16.8 94.0 0.409 0.026 A:P01024:0.026
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:735 B:1483 123.0 0.535 T -81.1 -5.3 110.0 0.478 0.057 A:P01024:0.057
TYR G:735 F:1483 119.0 0.517 T -81.0 -5.2 107.0 0.465 0.052 F:P01024:0.052
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:735 B:1483 117.0 0.509 T -80.6 -5.4 101.0 0.439 0.07 A:P01024:0.07
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR F:735 B:1461 123.0 0.535 S -88.0 -13.5 105.0 0.457 0.078 E:P01024:0.078
TYR H:735 H:1461 88.0 0.383 S -89.5 -15.5 67.0 0.291 0.092 G:P01024:0.091
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR H:735 B:1461 122.0 0.53 S -90.2 -10.7 105.0 0.457 0.073 G:P01024:0.074
TYR J:735 H:1461 121.0 0.526 T -89.3 -10.4 103.0 0.448 0.078 I:P01024:0.078
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 TYR B:735 B:1461 104.0 0.452 T -86.9 -5.2 99.0 0.43 0.022 A:P01024:0.022
 HOH
 1.814
 OH
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 TYR B:735 B:1461 116.0 0.504 T -79.2 -21.6 94.0 0.409 0.095 A:P01024:0.096
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:735 B:1461 137.0 0.596 S -102.0 -33.3 115.0 0.5 0.096 A:P01024:0.096
TYR D:735 D:1461 140.0 0.609 S -101.8 -33.3 NA NA NA
TYR F:735 F:1461 140.0 0.609 S -101.7 -33.1 NA NA NA
TYR H:735 H:1461 140.0 0.609 S -102.1 -32.9 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:735 B:1483 116.0 0.504 T -80.0 -5.6 112.0 0.487 0.017 A:P01024:0.017
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:735 B:1483 118.0 0.513 T -86.5 -6.0 112.0 0.487 0.026 A:P01024:0.026
 HOH
 2.125
 OH
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:735 B:1483 130.0 0.565 T -79.5 -25.8 NA NA NA
TYR E:735 E:1483 131.0 0.57 T -80.3 -24.3 105.0 0.457 0.113 D:P01024:0.113
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:735 B:1483 120.0 0.522 T -80.0 -20.8 106.0 0.461 0.061 A:P01024:0.061
TYR D:735 D:1483 118.0 0.513 T -79.0 -23.0 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:735 B:1483 121.0 0.526 T -75.2 -21.8 116.0 0.504 0.022 A:P01024:0.022
 HOH
 5.253
 CZ
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 TYR B:735 B:1483 129.0 0.561 T -87.8 -1.8 125.0 0.543 0.018 A:P01024:0.017
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 TYR B:735 B:1483 131.0 0.57 T -87.9 -1.7 130.0 0.565 0.005 A:None:0.004
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:732 B:1461 135.0 0.587 S -101.2 -36.5 113.0 0.491 0.096 A:P01024:0.096
TYR D:732 D:1461 137.0 0.596 S -101.0 -36.2 NA NA NA
2a74 3 P01024 100.0 0.0 X-RAY
 2005-09-27 TYR C:163 C:1461 120.0 0.522 T -78.5 -10.1 93.0 0.404 0.118 A:P01024:0.117
 HOH
 5.454
 OH
 O
TYR F:163 F:1461 130.0 0.565 T -82.7 -8.4 NA NA NA
2ice 3 P01024 100.0 0.0 X-RAY
 2006-11-07 TYR C:163 C:1461 120.0 0.522 T -91.5 -0.6 97.0 0.422 0.1 A:P01024:0.1
TYR G:163 F:1461 113.0 0.491 T -97.6 11.7 NA NA NA
2qki 3 P01024 100.0 0.0 X-RAY
 2007-08-14 TYR C:163 C:1461 128.0 0.557 T -86.8 -6.7 125.0 0.543 0.014 A:P01024:0.013
 HOH
 4.736
 CD2
 O
TYR F:163 F:1461 116.0 0.504 T -81.8 -13.5 NA NA NA
3l3o 4 P01024 100.0 0.0 X-RAY
 2010-08-04 TYR E:163 F:1461 112.0 0.487 S -59.4 -50.9 NA NA NA
TYR G:163 C:1461 111.0 0.483 S -59.3 -51.0 86.0 0.374 0.109 A:P01024:0.109
3nms 2 P01024 100.0 0.0 X-RAY
 2010-08-04 TYR B:163 C:1461 115.0 0.5 T -41.8 -59.9 88.0 0.383 0.117 A:P01024:0.117
3ohx 3 P01024 100.0 0.0 X-RAY
 2010-09-01 TYR C:163 C:1461 112.0 0.487 S -59.3 -51.0 86.0 0.374 0.113 A:P01024:0.113
TYR G:163 F:1461 112.0 0.487 S -59.3 -51.0 NA NA NA
3t4a 3 P01024 100.0 0.0 X-RAY
 2011-11-23 TYR C:163 C:1461 110.0 0.478 T -72.4 10.0 91.0 0.396 0.082 A:P01024:0.083
TYR F:163 F:1461 108.0 0.47 T -61.6 15.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 TYR A:1483 A:1483 8.0 0.035 S -82.8 -69.4