Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6680256 . C A CCDS32883.1:NM_000064.2:c.4369Gac>Tac_NP_000055.2:p.1457D>Y Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP B:786 B:1457 16.0 0.107 -92.2 77.7 16.0 0.107 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ASP B:785 B:1435 30.0 0.2 -108.1 81.6 30.0 0.2 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ASP B:709 B:1435 16.0 0.107 E -79.7 104.4 16.0 0.107 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ASP B:709 B:1435 54.0 0.36 E -100.8 106.5 54.0 0.36 0.0 HOH
 9.136
 OD2
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ASP B:709 B:1435 46.0 0.307 E -88.9 107.9 46.0 0.307 0.0
ASP D:709 D:1435 47.0 0.313 E -88.9 107.9 NA NA NA
ASP F:709 F:1435 44.0 0.293 E -88.9 107.6 NA NA NA
ASP H:709 H:1435 44.0 0.293 E -88.9 107.5 44.0 0.293 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ASP B:709 B:1435 30.0 0.2 E -76.8 116.4 30.0 0.2 0.0
ASP D:709 D:1435 34.0 0.227 E -78.8 117.2 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ASP B:709 B:1435 56.0 0.373 E -107.1 107.7 56.0 0.373 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ASP B:709 B:1457 60.0 0.4 E -93.9 121.0 60.0 0.4 0.0
ASP G:709 F:1457 69.0 0.46 E -94.4 121.3 69.0 0.46 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ASP B:709 B:1457 61.0 0.407 E -94.4 121.0 61.0 0.407 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP F:709 B:1435 41.0 0.273 E -103.2 133.0 41.0 0.273 0.0
ASP H:709 H:1435 54.0 0.36 E -103.2 134.2 54.0 0.36 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ASP H:709 B:1435 43.0 0.287 E -103.4 135.2 43.0 0.287 0.0
ASP J:709 H:1435 40.0 0.267 E -103.3 135.4 40.0 0.267 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ASP B:709 B:1435 28.0 0.187 E -97.6 130.5 28.0 0.187 0.0 HOH
 2.628
 OD2
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ASP B:709 B:1435 44.0 0.293 E -100.0 108.5 44.0 0.293 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ASP B:709 B:1435 49.0 0.327 -81.1 88.5 49.0 0.327 0.0
ASP D:709 D:1435 50.0 0.333 -81.7 88.9 NA NA NA
ASP F:709 F:1435 49.0 0.327 -81.3 88.9 NA NA NA
ASP H:709 H:1435 48.0 0.32 -81.5 88.4 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:709 B:1457 52.0 0.347 E -93.8 121.4 52.0 0.347 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:709 B:1457 30.0 0.2 E -100.2 118.3 30.0 0.2 0.0 HOH
 2.496
 OD2
 O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:709 B:1457 51.0 0.34 E -98.0 113.8 NA NA NA
ASP E:709 E:1457 30.0 0.2 E -99.6 113.0 30.0 0.2 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:709 B:1457 42.0 0.28 E -99.6 108.8 42.0 0.28 0.0
ASP D:709 D:1457 51.0 0.34 E -100.0 109.5 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ASP B:709 B:1457 37.0 0.247 E -92.2 119.6 37.0 0.247 0.0 HOH
 4.619
 OD2
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ASP B:709 B:1457 51.0 0.34 E -85.7 118.6 51.0 0.34 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ASP B:709 B:1457 50.0 0.333 E -85.7 118.6 50.0 0.333 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ASP B:706 B:1435 48.0 0.32 -79.9 71.9 48.0 0.32 0.0
ASP D:706 D:1435 48.0 0.32 -80.7 72.4 NA NA NA
2a74 3 P01024 100.0 0.0 X-RAY
 2005-09-27 ASP C:137 C:1435 46.0 0.307 E -90.5 110.4 46.0 0.307 0.0 HOH
 2.707
 OD1
 O
ASP F:137 F:1435 52.0 0.347 E -83.0 116.5 NA NA NA
2ice 3 P01024 100.0 0.0 X-RAY
 2006-11-07 ASP C:137 C:1435 30.0 0.2 E -87.8 115.4 30.0 0.2 0.0
ASP G:137 F:1435 25.0 0.167 E -76.0 83.3 NA NA NA
2qki 3 P01024 100.0 0.0 X-RAY
 2007-08-14 ASP C:137 C:1435 52.0 0.347 E -85.8 110.4 52.0 0.347 0.0 BR
HOH
 3.869
7.060
 OD1
OD2
 BR
O
ASP F:137 F:1435 60.0 0.4 E -97.6 115.1 NA NA NA
3l3o 4 P01024 100.0 0.0 X-RAY
 2010-08-04 ASP E:137 F:1435 39.0 0.26 E -99.3 119.8 NA NA NA
ASP G:137 C:1435 39.0 0.26 E -99.3 119.8 39.0 0.26 0.0
3nms 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ASP B:137 C:1435 34.0 0.227 B -113.0 116.2 34.0 0.227 0.0
3ohx 3 P01024 100.0 0.0 X-RAY
 2010-09-01 ASP C:137 C:1435 39.0 0.26 E -99.3 119.8 39.0 0.26 0.0
ASP G:137 F:1435 38.0 0.253 E -99.3 119.8 NA NA NA
3t4a 3 P01024 100.0 0.0 X-RAY
 2011-11-23 ASP C:137 C:1435 79.0 0.527 -56.9 105.2 79.0 0.527 0.0
ASP F:137 F:1435 43.0 0.287 E -65.4 102.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ASP A:1457 A:1457 27.0 0.18 E -79.7 109.6