Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6685122 . G A CCDS32883.1:NM_000064.2:c.3846taC>taT_NP_000055.2:p.1282Y>Y Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR B:611 B:1282 23.0 0.1 T -68.0 -24.1 23.0 0.1 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 TYR B:610 B:1260 9.0 0.039 H -62.8 -40.5 9.0 0.039 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 TYR B:534 B:1260 3.0 0.013 H -47.5 -49.3 3.0 0.013 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:534 B:1260 20.0 0.087 H -58.2 -41.7 20.0 0.087 0.0 GOL
HOH
 7.344
4.408
 N
CD2
 O3
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:534 B:1260 25.0 0.109 H -58.6 -21.9 25.0 0.109 0.0
TYR D:534 D:1260 21.0 0.091 H -58.6 -21.8 NA NA NA
TYR F:534 F:1260 21.0 0.091 H -58.5 -21.9 NA NA NA
TYR H:534 H:1260 20.0 0.087 H -67.7 -26.4 20.0 0.087 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 TYR B:534 B:1260 5.0 0.022 H -68.4 -42.0 5.0 0.022 0.0
TYR D:534 D:1260 18.0 0.078 H -64.0 -39.9 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 TYR B:534 B:1260 20.0 0.087 H -68.8 -9.0 20.0 0.087 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:534 B:1282 9.0 0.039 H -69.6 -38.2 9.0 0.039 0.0
TYR G:534 F:1282 13.0 0.057 H -69.1 -38.3 13.0 0.057 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:534 B:1282 16.0 0.07 H -69.0 -38.4 16.0 0.07 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR F:534 B:1260 8.0 0.035 H -60.6 -55.6 8.0 0.035 0.0
TYR H:534 H:1260 29.0 0.126 H -64.1 -53.6 29.0 0.126 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR H:534 B:1260 7.0 0.03 H -63.0 -43.3 7.0 0.03 0.0
TYR J:534 H:1260 6.0 0.026 H -62.9 -42.5 6.0 0.026 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 TYR B:534 B:1260 15.0 0.065 H -61.4 -47.4 15.0 0.065 0.0 HOH
 4.350
 CD2
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 TYR B:534 B:1260 35.0 0.152 T -70.5 -31.8 35.0 0.152 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:534 B:1260 6.0 0.026 H -73.9 -31.7 6.0 0.026 0.0
TYR D:534 D:1260 4.0 0.017 H -74.0 -31.3 NA NA NA
TYR F:534 F:1260 6.0 0.026 H -74.8 -31.2 NA NA NA
TYR H:534 H:1260 9.0 0.039 H -74.5 -31.3 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:534 B:1282 10.0 0.043 H -69.6 -38.5 10.0 0.043 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:534 B:1282 11.0 0.048 H -61.0 -42.1 11.0 0.048 0.0 EDO
EDO
HOH
 9.823
8.293
2.640
 CD2
CE2
OH
 O1
O2
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:534 B:1282 16.0 0.07 H -61.2 -57.1 NA NA NA
TYR E:534 E:1282 14.0 0.061 H -60.8 -58.0 14.0 0.061 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:534 B:1282 10.0 0.043 H -71.5 -33.4 10.0 0.043 0.0
TYR D:534 D:1282 22.0 0.096 T -70.9 -33.7 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:534 B:1282 15.0 0.065 H -60.7 -48.8 15.0 0.065 0.0 HOH
 5.634
 N
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 TYR B:534 B:1282 9.0 0.039 H -68.0 -35.1 9.0 0.039 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 TYR B:534 B:1282 10.0 0.043 H -68.0 -35.2 10.0 0.043 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:531 B:1260 14.0 0.061 H -69.6 -26.3 14.0 0.061 0.0
TYR D:531 D:1260 10.0 0.043 H -68.7 -27.2 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 TYR A:289 A:289 21.0 0.091 H -57.6 -51.5 21.0 0.091 0.0 HOH
 2.628
 OH
 O
TYR B:289 B:289 13.0 0.057 H -61.4 -47.1 13.0 0.057 0.0 HOH
 3.514
 HD2
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 TYR A:289 A:289 36.0 0.157 H -62.1 -46.6 36.0 0.157 0.0 HOH
 3.968
 HD2
 O
TYR C:289 B:289 18.0 0.078 H -61.5 -47.3 18.0 0.078 0.0 HOH
 3.626
 HD2
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 TYR A:289 A:296 52.0 0.226 H -57.7 -46.5 52.0 0.226 0.0 GOL
HOH
 7.845
4.116
 N
CD2
 C3
O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 TYR A:289 A:296 61.0 0.265 H -58.5 -48.1 61.0 0.265 0.0 GOL
HOH
 7.849
3.226
 N
OH
 C3
O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 TYR A:289 A:289 55.0 0.239 H -52.3 -44.7 55.0 0.239 0.0 HOH
 8.323
 O
 O
TYR C:289 B:289 63.0 0.274 H -61.6 -39.0 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 TYR A:296 A:289 48.0 0.209 H -53.9 -48.4 NA NA NA
TYR B:296 B:289 10.0 0.043 H -57.5 -48.0 10.0 0.043 0.0 HOH
 2.666
 OH
 O
TYR C:296 C:289 79.0 0.343 H -56.4 -53.7 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 TYR A:296 A:289 60.0 0.261 H -58.8 -44.3 60.0 0.261 0.0 HOH
 5.971
 N
 O
TYR B:296 B:289 18.0 0.078 H -53.6 -54.5 NA NA NA
TYR C:296 C:289 81.0 0.352 H -59.8 -53.0 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 TYR B:296 A:289 29.0 0.126 H -53.5 -49.7 NA NA NA
TYR D:296 B:289 8.0 0.035 H -52.6 -51.6 8.0 0.035 0.0 GOL
HOH
 9.614
2.514
 N
OH
 O3
O
TYR F:296 C:289 77.0 0.335 H -52.8 -54.3 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 TYR A:296 A:289 53.0 0.23 H -52.6 -49.4 53.0 0.23 0.0 HOH
 5.917
 N
 O
TYR B:296 B:289 8.0 0.035 H -50.2 -51.3 NA NA NA
TYR C:296 C:289 61.0 0.265 H -53.1 -50.4 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 TYR A:289 A:289 2.0 0.009 H -61.0 -44.2 2.0 0.009 0.0 HOH
 2.736
 OH
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 TYR A:292 A:1282 19.0 0.083 H -66.2 -46.5 19.0 0.083 0.0 NI
HOH
 5.606
4.614
 OH
CD2
 NI
O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 TYR A:289 A:1282 71.0 0.309 H -64.4 -45.9 71.0 0.309 0.0
TYR B:289 B:1282 48.0 NA H -63.0 -54.3 NA NA NA
TYR C:289 C:1282 63.0 0.274 H -64.1 -45.9 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 TYR A:292 A:1282 11.0 0.048 H -57.5 -46.5 11.0 0.048 0.0 HOH
 4.962
 CD2
 O
TYR C:292 C:1282 13.0 0.057 H -55.9 -47.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 TYR A:292 A:1282 65.0 0.283 H -74.6 -63.9 65.0 0.283 0.0 HOH
 7.274
 O
 O
TYR C:292 C:1282 16.0 NA H -63.6 -55.4 NA NA NA
TYR E:292 E:1282 9.0 NA H -90.4 -49.3 NA NA NA
TYR G:292 G:1282 13.0 NA H -77.0 -49.3 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 TYR A:292 A:293 9.0 0.039 H -56.5 -52.6 9.0 0.039 0.0 HOH
 4.978
 CD2
 O
TYR C:292 B:293 10.0 0.043 H -58.2 -49.7 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 TYR A:292 A:293 9.0 0.039 H -58.9 -55.2 9.0 0.039 0.0 HOH
 4.954
 CD2
 O
TYR C:292 B:293 9.0 0.039 H -58.9 -53.6 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 TYR A:289 A:289 59.0 0.257 H -64.5 -46.5 59.0 0.257 0.0 HOH
 6.100
 N
 O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 TYR A:289 A:289 69.0 0.3 H -59.3 -46.4 69.0 0.3 0.0 HOH
 6.124
 N
 O
TYR B:289 B:289 85.0 0.37 H -57.8 -38.6 85.0 0.37 0.0 HOH
 6.070
 N
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 TYR A:273 A:1282 56.0 0.243 H -56.9 -45.1 56.0 0.243 0.0 HOH
 5.779
 N
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 TYR A:273 A:1282 87.0 0.378 H -57.0 -42.9 87.0 0.378 0.0 HOH
 6.335
 N
 O
TYR B:273 B:1282 89.0 0.387 H -56.2 -42.0 89.0 0.387 0.0 HOH
 6.005
 N
 O
TYR C:273 C:1282 88.0 0.383 H -58.7 -41.1 NA NA NA
TYR D:273 D:1282 71.0 0.309 H -57.8 -40.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 TYR A:1282 A:1282 9.0 0.039 H -59.1 -51.7