Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6686137 . G A CCDS32883.1:NM_000064.2:c.3808Cag>Tag_NP_000055.2:p.1270Q>* Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 GLN B:599 B:1270 0.0 0.0 H -60.4 -39.3 0.0 0.0 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 GLN B:598 B:1248 3.0 0.017 H -53.8 -38.3 3.0 0.017 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 GLN B:522 B:1248 0.0 0.0 H -68.5 -53.6 0.0 0.0 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLN B:522 B:1248 2.0 0.011 H -71.1 -42.4 2.0 0.011 0.0 GOL
HOH
 9.523
2.679
 NE2
OE1
 C3
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 GLN B:522 B:1248 2.0 0.011 H -76.5 -38.2 2.0 0.011 0.0
GLN D:522 D:1248 2.0 0.011 H -76.5 -38.2 NA NA NA
GLN F:522 F:1248 1.0 0.006 H -76.4 -38.3 NA NA NA
GLN H:522 H:1248 1.0 0.006 H -84.2 -35.1 1.0 0.006 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 GLN B:522 B:1248 3.0 0.017 H -74.6 -34.6 3.0 0.017 0.0
GLN D:522 D:1248 1.0 0.006 H -69.1 -51.7 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 GLN B:522 B:1248 0.0 0.0 T -107.8 -28.9 0.0 0.0 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLN B:522 B:1270 2.0 0.011 H -64.9 -48.4 2.0 0.011 0.0
GLN G:522 F:1270 2.0 0.011 H -64.7 -48.5 2.0 0.011 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 GLN B:522 B:1270 1.0 0.006 H -64.8 -47.8 1.0 0.006 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 GLN F:522 B:1248 2.0 0.011 H -74.6 -37.4 2.0 0.011 0.0
GLN H:522 H:1248 4.0 0.022 H -76.8 -36.8 4.0 0.022 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 GLN H:522 B:1248 1.0 0.006 H -71.8 -39.4 1.0 0.006 0.0
GLN J:522 H:1248 0.0 0.0 H -72.5 -37.6 0.0 0.0 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 GLN B:522 B:1248 1.0 0.006 H -66.9 -43.3 1.0 0.006 0.0 PEG
HOH
 9.434
2.739
 NE2
OE1
 C1
O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 GLN B:522 B:1248 0.0 0.0 H -69.2 -51.4 0.0 0.0 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLN B:522 B:1248 0.0 0.0 H -75.6 -48.8 0.0 0.0 0.0
GLN D:522 D:1248 0.0 0.0 H -75.4 -49.0 NA NA NA
GLN F:522 F:1248 0.0 0.0 H -75.5 -48.9 NA NA NA
GLN H:522 H:1248 0.0 0.0 H -75.1 -49.3 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLN B:522 B:1270 3.0 0.017 H -64.7 -48.6 3.0 0.017 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLN B:522 B:1270 1.0 0.006 H -64.5 -39.8 1.0 0.006 0.0 EDO
EDO
HOH
 9.907
9.319
2.755
 NE2
N
OE1
 C1
O1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLN B:522 B:1270 3.0 0.017 H -64.8 -46.2 NA NA NA
GLN E:522 E:1270 2.0 0.011 H -66.7 -45.4 2.0 0.011 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLN B:522 B:1270 2.0 0.011 H -67.5 -49.1 2.0 0.011 0.0
GLN D:522 D:1270 1.0 0.006 H -69.9 -51.4 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 GLN B:522 B:1270 2.0 0.011 H -66.2 -45.4 2.0 0.011 0.0 HOH
 3.157
 N
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 GLN B:522 B:1270 2.0 0.011 H -69.6 -41.1 2.0 0.011 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 GLN B:522 B:1270 2.0 0.011 H -69.6 -41.1 2.0 0.011 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 GLN B:519 B:1248 0.0 0.0 H -82.3 -37.7 0.0 0.0 0.0
GLN D:519 D:1248 0.0 0.0 H -83.3 -36.1 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLN A:277 A:277 1.0 0.006 H -70.4 -39.7 1.0 0.006 0.0 HOH
 2.313
 H
 O
GLN B:277 B:277 2.0 0.011 H -72.8 -43.2 2.0 0.011 0.0 HOH
 2.283
 H
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 GLN A:277 A:277 1.0 0.006 H -66.0 -41.5 1.0 0.006 0.0 HOH
 2.271
 H
 O
GLN C:277 B:277 1.0 0.006 H -71.9 -40.5 1.0 0.006 0.0 EDO
HOH
 8.833
2.167
 HG3
H
 H22
O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLN A:277 A:284 1.0 0.006 H -71.1 -40.8 1.0 0.006 0.0 GOL
HOH
 9.285
2.684
 OE1
NE2
 C3
O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 GLN A:277 A:284 1.0 0.006 H -70.4 -41.7 1.0 0.006 0.0 GOL
HOH
 9.283
2.680
 NE2
OE1
 C3
O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 GLN A:277 A:277 0.0 0.0 H -67.9 -50.7 0.0 0.0 0.0
GLN C:277 B:277 1.0 0.006 H -56.6 -46.8 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 GLN A:284 A:277 0.0 0.0 H -67.3 -45.2 NA NA NA
GLN B:284 B:277 1.0 0.006 H -64.2 -42.6 1.0 0.006 0.0 GOL
HOH
 9.970
2.752
 NE2
OE1
 C3
O
GLN C:284 C:277 2.0 0.011 H -71.3 -42.9 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 GLN A:284 A:277 0.0 0.0 H -66.2 -47.0 0.0 0.0 0.0 GOL
HOH
 9.781
2.689
 NE2
OE1
 C3
O
GLN B:284 B:277 1.0 0.006 H -63.2 -46.4 NA NA NA
GLN C:284 C:277 2.0 0.011 H -76.7 -44.4 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 GLN B:284 A:277 0.0 0.0 H -68.2 -46.2 NA NA NA
GLN D:284 B:277 0.0 0.0 H -67.5 -42.3 0.0 0.0 0.0 GOL
HOH
 9.878
2.591
 NE2
OE1
 C3
O
GLN F:284 C:277 1.0 0.006 H -69.2 -47.5 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 GLN A:284 A:277 1.0 0.006 H -70.3 -46.1 1.0 0.006 0.0 GOL
HOH
 9.667
2.625
 NE2
OE1
 C3
O
GLN B:284 B:277 1.0 0.006 H -71.2 -46.2 NA NA NA
GLN C:284 C:277 2.0 0.011 H -69.4 -46.6 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 GLN A:277 A:277 2.0 0.011 H -68.5 -40.1 2.0 0.011 0.0 HOH
 2.754
 OE1
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 GLN A:280 A:1270 2.0 0.011 H -67.3 -44.4 2.0 0.011 0.0 HOH
 2.669
 OE1
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 GLN A:277 A:1270 2.0 0.011 H -76.0 -49.6 2.0 0.011 0.0
GLN B:277 B:1270 0.0 0.0 H -75.1 -47.7 NA NA NA
GLN C:277 C:1270 0.0 0.0 H -75.3 -49.6 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 GLN A:280 A:1270 2.0 0.011 H -72.5 -43.2 2.0 0.011 0.0 HOH
 2.646
 OE1
 O
GLN C:280 C:1270 1.0 0.006 H -70.4 -43.4 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 GLN A:280 A:1270 1.0 0.006 H -58.5 -47.4 1.0 0.006 0.0 HOH
 2.693
 N
 O
GLN C:280 C:1270 2.0 0.011 H -76.3 -29.1 NA NA NA
GLN E:280 E:1270 2.0 0.011 H -86.3 -32.4 NA NA NA
GLN G:280 G:1270 2.0 0.011 H -62.3 -42.9 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 GLN A:280 A:281 2.0 0.011 H -62.4 -42.2 2.0 0.011 0.0 HOH
 2.680
 OE1
 O
GLN C:280 B:281 2.0 0.011 H -61.2 -43.6 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 GLN A:280 A:281 2.0 0.011 H -66.6 -41.0 2.0 0.011 0.0 HOH
 2.760
 OE1
 O
GLN C:280 B:281 1.0 0.006 H -64.8 -38.9 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 GLN A:277 A:277 1.0 0.006 H -65.8 -43.8 1.0 0.006 0.0 GOL
GOL
HOH
 9.477
8.646
2.768
 NE2
N
OE1
 C1
C1
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 GLN A:277 A:277 1.0 0.006 H -62.2 -46.4 1.0 0.006 0.0 HOH
 2.888
 OE1
 O
GLN B:277 B:277 1.0 0.006 H -68.5 -36.7 1.0 0.006 0.0 HOH
 3.006
 N
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLN A:261 A:1270 1.0 0.006 H -68.7 -39.5 1.0 0.006 0.0 HOH
 2.796
 OE1
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 GLN A:261 A:1270 2.0 0.011 H -64.2 -39.1 2.0 0.011 0.0 HOH
 2.428
 OE1
 O
GLN B:261 B:1270 1.0 0.006 H -62.7 -39.3 1.0 0.006 0.0 HOH
 2.689
 OE1
 O
GLN C:261 C:1270 1.0 0.006 H -63.9 -38.4 NA NA NA
GLN D:261 D:1270 2.0 0.011 H -63.6 -39.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 GLN A:1270 A:1270 2.0 0.011 H -74.2 -29.0