Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6693044 . G A CCDS32883.1:NM_000064.2:c.3281gCc>gTc_NP_000055.2:p.1094A>V Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA B:423 B:1094 88.0 0.765 -86.4 110.8 64.0 0.557 0.208 A:P01024:0.209
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 ALA B:422 B:1072 85.0 0.739 -74.3 112.6 71.0 0.617 0.122 A:P01024:0.122
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 ALA B:346 B:1072 93.0 0.809 -75.0 95.6 93.0 0.809 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:346 B:1072 81.0 0.704 -81.0 115.8 23.0 0.2 0.504 C:P08603:0.504
 HOH
 4.305
 CB
 O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 ALA B:346 B:1072 89.0 0.774 -91.5 90.5 89.0 0.774 0.0
ALA D:346 D:1072 86.0 0.748 -91.4 90.5 NA NA NA
ALA F:346 F:1072 86.0 0.748 -91.5 90.5 NA NA NA
ALA H:346 H:1072 89.0 0.774 -92.1 90.1 89.0 0.774 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 ALA B:346 B:1072 83.0 0.722 -75.0 102.3 83.0 0.722 0.0
ALA D:346 D:1072 88.0 0.765 -67.6 120.3 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 ALA B:346 B:1072 59.0 0.513 -75.6 109.7 59.0 0.513 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:346 B:1094 80.0 0.696 -80.5 103.7 16.0 0.139 0.557 C:P08603:0.557
ALA G:346 F:1094 76.0 0.661 -80.8 103.6 18.0 0.157 0.504 H:P08603:0.504
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 ALA B:346 B:1094 76.0 0.661 -80.7 103.9 21.0 0.183 0.478 C:P08603:0.478
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA F:346 B:1072 87.0 0.757 -88.2 89.7 87.0 0.757 0.0
ALA H:346 H:1072 89.0 0.774 -89.2 92.3 89.0 0.774 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 ALA H:346 B:1072 89.0 0.774 -87.9 88.5 89.0 0.774 0.0
ALA J:346 H:1072 86.0 0.748 -88.5 88.7 86.0 0.748 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 ALA B:346 B:1072 88.0 0.765 -82.7 105.4 88.0 0.765 0.0 HOH
 3.028
 N
 O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 ALA B:346 B:1072 90.0 0.783 -85.1 90.5 90.0 0.783 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:346 B:1072 85.0 0.739 -95.5 115.7 85.0 0.739 0.0
ALA D:346 D:1072 83.0 0.722 -95.3 115.5 NA NA NA
ALA F:346 F:1072 83.0 0.722 -95.6 115.6 NA NA NA
ALA H:346 H:1072 83.0 0.722 -95.4 115.9 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:346 B:1094 79.0 0.687 -80.4 103.4 79.0 0.687 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:346 B:1094 96.0 0.835 -71.2 105.7 24.0 0.209 0.626 C:P15529:0.626
 EDO
HOH
 7.621
3.220
 N
N
 O1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:346 B:1094 90.0 0.783 -66.6 129.1 NA NA NA
ALA E:346 E:1094 92.0 0.8 -67.6 130.6 92.0 0.8 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:346 B:1094 85.0 0.739 -85.5 89.8 85.0 0.739 0.0
ALA D:346 D:1094 94.0 0.817 -84.4 90.3 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 ALA B:346 B:1094 75.0 0.652 -67.2 114.3 18.0 0.157 0.495 C:Q76U65:0.496
 HOH
 5.460
 O
 O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 ALA B:346 B:1094 73.0 0.635 -145.6 148.7 73.0 0.635 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 ALA B:346 B:1094 74.0 0.643 -145.6 148.8 74.0 0.643 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 ALA B:343 B:1072 84.0 0.73 -87.3 116.0 84.0 0.73 0.0
ALA D:343 D:1072 82.0 0.713 -87.6 115.4 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:101 A:101 89.0 0.774 -82.3 115.0 89.0 0.774 0.0 HOH
 2.285
 H
 O
ALA B:101 B:101 88.0 0.765 -81.7 115.2 88.0 0.765 0.0 HOH
 2.281
 H
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 ALA A:101 A:101 84.0 0.73 -79.8 131.0 37.0 0.322 0.408 B:Q931F4:0.409
 HOH
 2.337
 H
 O
ALA C:101 B:101 83.0 0.722 -74.6 131.3 36.0 0.313 0.409 D:Q931F4:0.409
 HOH
 2.093
 H
 O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:101 A:108 89.0 0.774 -64.6 131.3 89.0 0.774 0.0 HOH
 2.677
 O
 O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 ALA A:101 A:108 90.0 0.783 -64.3 131.0 43.0 0.374 0.409 B:C8LN82:0.409
 HOH
 2.670
 O
 O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 ALA A:101 A:101 93.0 0.809 -53.7 144.4 18.0 0.157 0.652 B:P20023:0.652
ALA C:101 B:101 90.0 0.783 -63.3 137.4 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 ALA A:108 A:101 85.0 0.739 -79.4 116.6 NA NA NA
ALA B:108 B:101 84.0 0.73 -78.4 106.4 84.0 0.73 0.0 HOH
 2.765
 O
 O
ALA C:108 C:101 83.0 0.722 -77.6 107.6 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 ALA A:108 A:101 91.0 0.791 -87.9 104.4 91.0 0.791 0.0 HOH
 2.786
 O
 O
ALA B:108 B:101 88.0 0.765 -81.2 98.6 NA NA NA
ALA C:108 C:101 81.0 0.704 -69.4 104.1 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 ALA B:108 A:101 90.0 0.783 -87.2 116.5 NA NA NA
ALA D:108 B:101 89.0 0.774 -81.2 114.8 89.0 0.774 0.0 HOH
 2.601
 O
 O
ALA F:108 C:101 89.0 0.774 -85.6 99.9 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 ALA A:108 A:101 87.0 0.757 -83.7 116.3 87.0 0.757 0.0 HOH
 3.378
 N
 O
ALA B:108 B:101 90.0 0.783 -80.7 112.8 NA NA NA
ALA C:108 C:101 88.0 0.765 -79.5 113.8 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 ALA A:101 A:101 90.0 0.783 -81.9 108.0 90.0 0.783 0.0 HOH
 2.739
 O
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 ALA A:104 A:1094 93.0 0.809 -77.6 100.7 93.0 0.809 0.0
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 ALA A:101 A:1094 86.0 0.748 -87.2 104.1 86.0 0.748 0.0
ALA B:101 B:1094 88.0 0.765 -88.6 105.6 NA NA NA
ALA C:101 C:1094 85.0 0.739 -85.0 102.9 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 ALA A:104 A:1094 91.0 0.791 -56.4 124.0 41.0 0.357 0.434 B:P68799:0.435
 HOH
 2.639
 O
 O
ALA C:104 C:1094 84.0 0.73 -64.2 126.6 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 ALA A:104 A:1094 82.0 0.713 -69.1 132.9 37.0 0.322 0.391 B:Q99UV2:0.391
 HOH
 4.400
 N
 O
ALA C:104 C:1094 79.0 0.687 -70.6 142.9 NA NA NA
ALA E:104 E:1094 79.0 0.687 -67.1 130.1 NA NA NA
ALA G:104 G:1094 86.0 0.748 -61.6 145.5 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 ALA A:104 A:105 88.0 0.765 -71.7 128.2 41.0 0.357 0.408 B:A6QG59:0.409
 HOH
 2.905
 N
 O
ALA C:104 B:105 90.0 0.783 -72.8 129.6 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 ALA A:104 A:105 89.0 0.774 -67.9 131.6 41.0 0.357 0.417 B:A6QG59:0.417
 HOH
 2.741
 O
 O
ALA C:104 B:105 90.0 0.783 -67.9 126.8 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 ALA A:101 A:101 87.0 0.757 -81.9 104.5 87.0 0.757 0.0 GOL
HOH
 3.921
2.773
 N
O
 O1
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 ALA A:101 A:101 96.0 0.835 -77.2 112.0 96.0 0.835 0.0 HOH
 3.275
 CA
 O
ALA B:101 B:101 88.0 0.765 -76.2 116.2 64.0 0.557 0.208 C:P08603:0.209
 HOH
 4.254
 CA
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ALA A:85 A:1094 96.0 0.835 -66.3 120.3 96.0 0.835 0.0 HOH
 2.785
 O
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 ALA A:85 A:1094 93.0 0.809 -74.2 117.3 93.0 0.809 0.0 HOH
 2.998
 CA
 O
ALA B:85 B:1094 94.0 0.817 -75.9 119.5 94.0 0.817 0.0 HOH
 2.463
 N
 O
ALA C:85 C:1094 92.0 0.8 -73.8 118.9 NA NA NA
ALA D:85 D:1094 93.0 0.809 -74.1 119.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ALA A:1094 A:1094 93.0 0.809 -72.1 91.1