Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6693082 . G A CCDS32883.1:NM_000064.2:c.3243taC>taT_NP_000055.2:p.1081Y>Y Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ru5 2 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR B:410 B:1081 1.0 0.004 H -64.2 -42.0 1.0 0.004 0.0
2a73 2 P01024 100.0 0.0 X-RAY
 2005-09-27 TYR B:409 B:1059 5.0 0.022 H -54.7 -55.4 5.0 0.022 0.0
2icf 2 P01024 100.0 0.0 X-RAY
 2006-11-07 TYR B:333 B:1059 0.0 0.0 H -57.6 -28.2 0.0 0.0 0.0
2wii 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:333 B:1059 0.0 0.0 H -71.2 -40.2 0.0 0.0 0.0 GOL
HOH
 8.941
5.989
 CB
OH
 C3
O
2win 2 P01024 100.0 0.0 X-RAY
 2009-06-09 TYR B:333 B:1059 0.0 0.0 H -73.7 -34.7 0.0 0.0 0.0
TYR D:333 D:1059 0.0 0.0 H -73.8 -34.7 NA NA NA
TYR F:333 F:1059 0.0 0.0 H -73.8 -34.7 NA NA NA
TYR H:333 H:1059 0.0 0.0 H -79.2 -33.5 0.0 0.0 0.0
3g6j 2 P01024 100.0 0.0 X-RAY
 2009-03-10 TYR B:333 B:1059 0.0 0.0 H -66.9 -34.7 0.0 0.0 0.0
TYR D:333 D:1059 0.0 0.0 H -69.1 -38.9 NA NA NA
3l5n 2 P01024 100.0 0.0 X-RAY
 2010-08-04 TYR B:333 B:1059 0.0 0.0 S -117.7 -0.9 0.0 0.0 0.0
5o32 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:333 B:1081 0.0 0.0 H -72.1 -36.2 0.0 0.0 0.0
TYR G:333 F:1081 0.0 0.0 H -72.1 -36.1 0.0 0.0 0.0
5o35 2 P01024 100.0 0.0 X-RAY
 2017-06-28 TYR B:333 B:1081 0.0 0.0 H -72.6 -36.9 0.0 0.0 0.0
6rur 4 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR F:333 B:1059 0.0 0.0 H -63.9 -42.0 0.0 0.0 0.0
TYR H:333 H:1059 0.0 0.0 H -64.3 -40.8 0.0 0.0 0.0
6ruv 5 P01024 100.0 0.0 X-RAY
 2019-08-21 TYR H:333 B:1059 0.0 0.0 H -70.7 -38.6 0.0 0.0 0.0
TYR J:333 H:1059 0.0 0.0 H -70.3 -37.6 0.0 0.0 0.0
7bag 2 P01024 100.0 0.0 X-RAY
 2022-01-12 TYR B:333 B:1059 0.0 0.0 H -70.7 -34.2 0.0 0.0 0.0 PEG
HOH
 8.893
5.494
 CB
OH
 C1
O
2i07 2 P01024 99.89 0.0 X-RAY
 2006-10-24 TYR B:333 B:1059 0.0 0.0 H -92.2 -38.0 0.0 0.0 0.0
2xwj 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:333 B:1059 0.0 0.0 H -69.2 -40.8 0.0 0.0 0.0
TYR D:333 D:1059 0.0 0.0 H -69.3 -40.5 NA NA NA
TYR F:333 F:1059 0.0 0.0 H -68.9 -40.1 NA NA NA
TYR H:333 H:1059 0.0 0.0 H -69.0 -40.8 NA NA NA
5fo7 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:333 B:1081 0.0 0.0 H -72.7 -36.8 0.0 0.0 0.0
5fo8 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:333 B:1081 0.0 0.0 H -68.3 -40.1 0.0 0.0 0.0 EDO
EDO
HOH
 9.035
9.566
5.599
 CB
OH
OH
 O1
O1
O
5fo9 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:333 B:1081 0.0 0.0 H -74.3 -34.0 NA NA NA
TYR E:333 E:1081 0.0 0.0 H -74.5 -34.1 0.0 0.0 0.0
5foa 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:333 B:1081 2.0 0.009 H -90.3 -39.4 2.0 0.009 0.0
TYR D:333 D:1081 2.0 0.009 H -90.9 -38.4 NA NA NA
5fob 2 P01024 99.89 0.0 X-RAY
 2016-04-06 TYR B:333 B:1081 0.0 0.0 H -71.9 -42.1 0.0 0.0 0.0 IOD
HOH
 9.918
7.270
 CB
OH
 I
O
6ehg 2 P01024 99.78 0.0 X-RAY
 2018-02-14 TYR B:333 B:1081 0.0 0.0 H -83.2 -29.6 0.0 0.0 0.0
6yo6 2 ? 99.78 0.0 X-RAY
 2021-02-24 TYR B:333 B:1081 0.0 0.0 H -83.2 -29.6 0.0 0.0 0.0
2xwb 2 P01024 99.89 0.0 X-RAY
 2011-01-12 TYR B:330 B:1059 0.0 0.0 H -66.3 -39.0 0.0 0.0 0.0
TYR D:330 D:1059 0.0 0.0 H -67.4 -39.0 NA NA NA
6rmt 1 P01024 99.68 0.0 X-RAY
 2020-11-18 TYR A:88 A:88 0.0 0.0 H -70.3 -37.8 0.0 0.0 0.0 HOH
 5.007
 HA
 O
TYR B:88 B:88 0.0 0.0 H -71.7 -41.2 0.0 0.0 0.0 HOH
 5.016
 HA
 O
6rmu 1 P01024 99.68 0.0 X-RAY
 2020-11-18 TYR A:88 A:88 0.0 0.0 H -69.2 -38.7 0.0 0.0 0.0 HOH
 4.840
 HD1
 O
TYR C:88 B:88 0.0 0.0 H -67.8 -37.1 0.0 0.0 0.0 EDO
HOH
 7.564
4.999
 HB2
HH
 HO2
O
2wy7 1 P01024 99.35 0.0 X-RAY
 2010-12-01 TYR A:88 A:95 0.0 0.0 H -66.8 -44.9 0.0 0.0 0.0 GOL
HOH
 8.827
3.591
 CB
CE1
 C3
O
2wy8 1 P01024 99.35 0.0 X-RAY
 2010-12-01 TYR A:88 A:95 0.0 0.0 H -66.4 -44.7 0.0 0.0 0.0 GOL
HOH
 8.833
3.583
 CB
CE1
 C3
O
3oed 1 P01024 99.35 0.0 X-RAY
 2011-05-11 TYR A:88 A:88 0.0 0.0 H -66.5 -40.2 0.0 0.0 0.0
TYR C:88 B:88 0.0 0.0 H -65.4 -41.8 NA NA NA
3oxu 1 P01024 99.68 0.0 X-RAY
 2011-02-16 TYR A:95 A:88 0.0 0.0 H -68.5 -42.1 NA NA NA
TYR B:95 B:88 0.0 0.0 H -66.3 -43.2 0.0 0.0 0.0 GOL
HOH
 9.185
3.661
 CB
CE1
 O3
O
TYR C:95 C:88 0.0 0.0 H -70.7 -41.8 NA NA NA
3rj3 1 P01024 99.68 0.0 X-RAY
 2012-03-14 TYR A:95 A:88 0.0 0.0 H -66.9 -39.4 0.0 0.0 0.0 GOL
HOH
 9.032
5.615
 CB
CA
 O3
O
TYR B:95 B:88 0.0 0.0 H -67.1 -41.6 NA NA NA
TYR C:95 C:88 0.0 0.0 H -66.8 -39.4 NA NA NA
4ont 2 P01024 99.68 0.0 X-RAY
 2014-11-26 TYR B:95 A:88 0.0 0.0 H -68.9 -39.1 NA NA NA
TYR D:95 B:88 0.0 0.0 H -65.2 -39.0 0.0 0.0 0.0 GOL
HOH
 9.062
3.667
 CB
CE1
 O3
O
TYR F:95 C:88 0.0 0.0 H -77.4 -38.6 NA NA NA
4zh1 1 P01024 99.68 0.0 X-RAY
 2016-01-13 TYR A:95 A:88 0.0 0.0 H -69.0 -37.9 0.0 0.0 0.0 GOL
HOH
 8.967
5.820
 CB
CA
 O3
O
TYR B:95 B:88 0.0 0.0 H -68.5 -40.7 NA NA NA
TYR C:95 C:88 0.0 0.0 H -70.2 -38.5 NA NA NA
1ghq 1 P01024 99.02 0.0 X-RAY
 2001-06-13 TYR A:88 A:88 0.0 0.0 H -72.5 -35.3 0.0 0.0 0.0 HOH
 5.743
 OH
 O
4m76 1 P01024 99.66 0.0 X-RAY
 2013-10-02 TYR A:91 A:1081 0.0 0.0 H -82.3 -32.3 0.0 0.0 0.0 HOH
 6.145
 CE1
 O
5nbq 1 P01024 99.66 0.0 X-RAY
 2017-12-06 TYR A:88 A:1081 0.0 0.0 H -70.9 -41.4 0.0 0.0 0.0
TYR B:88 B:1081 0.0 0.0 H -71.2 -39.2 NA NA NA
TYR C:88 C:1081 0.0 0.0 H -69.6 -41.8 NA NA NA
2gox 1 P01024 98.98 0.0 X-RAY
 2007-03-20 TYR A:91 A:1081 0.0 0.0 H -72.3 -36.3 0.0 0.0 0.0 HOH
 5.555
 OH
 O
TYR C:91 C:1081 0.0 0.0 H -67.9 -43.0 NA NA NA
2noj 1 P01024 98.98 0.0 X-RAY
 2007-08-14 TYR A:91 A:1081 0.0 0.0 H -64.1 -50.2 0.0 0.0 0.0 HOH
 6.007
 CD1
 O
TYR C:91 C:1081 0.0 0.0 H -63.1 -46.5 NA NA NA
TYR E:91 E:1081 0.0 0.0 H -68.1 -43.7 NA NA NA
TYR G:91 G:1081 0.0 0.0 H -73.5 -52.0 NA NA NA
3d5r 1 P01024 98.98 0.0 X-RAY
 2008-09-09 TYR A:91 A:92 0.0 0.0 H -69.1 -38.6 0.0 0.0 0.0 HOH
 5.515
 OH
 O
TYR C:91 B:92 0.0 0.0 H -70.1 -39.1 NA NA NA
3d5s 1 P01024 98.98 0.0 X-RAY
 2008-09-16 TYR A:91 A:92 0.0 0.0 H -66.7 -36.8 0.0 0.0 0.0 HOH
 5.693
 OH
 O
TYR C:91 B:92 0.0 0.0 H -69.7 -34.6 NA NA NA
1c3d 1 P01024 99.32 0.0 X-RAY
 1998-10-07 TYR A:88 A:88 0.0 0.0 H -66.9 -40.4 0.0 0.0 0.0 GOL
GOL
HOH
 9.039
9.635
5.770
 CB
OH
OH
 O1
C3
O
2xqw 1 P01024 99.32 0.0 X-RAY
 2011-02-02 TYR A:88 A:88 0.0 0.0 H -63.0 -40.4 0.0 0.0 0.0 HOH
 5.534
 OH
 O
TYR B:88 B:88 0.0 0.0 H -71.6 -39.4 0.0 0.0 0.0 HOH
 5.647
 CA
 O
1qqf 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 TYR A:72 A:1081 0.0 0.0 H -64.4 -40.8 0.0 0.0 0.0 HOH
 5.914
 OH
 O
1qsj 1 P01026 84.06 7e-156 X-RAY
 2000-07-31 TYR A:72 A:1081 0.0 0.0 H -71.0 -34.3 0.0 0.0 0.0 HOH
 2.796
 O
 O
TYR B:72 B:1081 0.0 0.0 H -70.7 -34.5 0.0 0.0 0.0 HOH
 0.867
 OH
 O
TYR C:72 C:1081 0.0 0.0 H -72.0 -34.1 NA NA NA
TYR D:72 D:1081 0.0 0.0 H -70.2 -33.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 TYR A:1081 A:1081 3.0 0.013 H -63.6 -41.1