Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 6697759 | . | G | A | CCDS32883.1:NM_000064.2:c.2487ttC>ttT_NP_000055.2:p.829F>F | Homo sapiens complement component 3 (C3), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6ru5 | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | PHE | B:158 | B:829 | 9.0 | 0.043 | E | -122.3 | 109.1 | 1.0 | 0.005 | 0.038 |
C:None:0.038 |
|||||
2a73 | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2005-09-27 | PHE | B:157 | B:807 | 2.0 | 0.01 | E | -114.7 | 139.1 | 2.0 | 0.01 | 0.0 | ||||||
2icf | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | PHE | B:81 | B:807 | 4.0 | 0.019 | E | -136.7 | 141.7 | 4.0 | 0.019 | 0.0 | ||||||
2wii | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | PHE | B:81 | B:807 | 4.0 | 0.019 | E | -130.0 | 123.1 | 4.0 | 0.019 | 0.0 |
GOL HOH |
8.714 8.757 |
CZ N |
C1 O |
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2win | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | PHE | B:81 | B:807 | 0.0 | 0.0 | E | -144.7 | 135.3 | 0.0 | 0.0 | 0.0 | ||||||
PHE | D:81 | D:807 | 1.0 | 0.005 | E | -146.4 | 135.4 | NA | NA | NA | |||||||||||||
PHE | F:81 | F:807 | 0.0 | 0.0 | E | -147.4 | 135.9 | NA | NA | NA | |||||||||||||
PHE | H:81 | H:807 | 0.0 | 0.0 | E | -151.6 | 136.5 | 0.0 | 0.0 | 0.0 | |||||||||||||
3g6j | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-03-10 | PHE | B:81 | B:807 | 10.0 | 0.048 | E | -141.9 | 129.3 | 10.0 | 0.048 | 0.0 | ||||||
PHE | D:81 | D:807 | 8.0 | 0.038 | E | -143.9 | 136.1 | NA | NA | NA | |||||||||||||
3l5n | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | PHE | B:81 | B:807 | 0.0 | 0.0 | S | -167.9 | 123.1 | 0.0 | 0.0 | 0.0 | ||||||
5o32 | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | PHE | B:81 | B:829 | 4.0 | 0.019 | E | -136.5 | 127.9 | 4.0 | 0.019 | 0.0 | ||||||
PHE | G:81 | F:829 | 5.0 | 0.024 | E | -136.2 | 128.0 | 5.0 | 0.024 | 0.0 | |||||||||||||
5o35 | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | PHE | B:81 | B:829 | 6.0 | 0.029 | E | -135.9 | 128.0 | 6.0 | 0.029 | 0.0 | ||||||
6rur | 4 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | PHE | F:81 | B:807 | 5.0 | 0.024 | E | -128.8 | 132.0 | 5.0 | 0.024 | 0.0 | ||||||
PHE | H:81 | H:807 | 4.0 | 0.019 | E | -130.4 | 133.3 | 4.0 | 0.019 | 0.0 | |||||||||||||
6ruv | 5 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | PHE | H:81 | B:807 | 5.0 | 0.024 | E | -127.4 | 129.8 | 5.0 | 0.024 | 0.0 | ||||||
PHE | J:81 | H:807 | 2.0 | 0.01 | E | -129.0 | 129.4 | 2.0 | 0.01 | 0.0 | |||||||||||||
7bag | 2 | P01024 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | PHE | B:81 | B:807 | 4.0 | 0.019 | E | -137.2 | 129.2 | 4.0 | 0.019 | 0.0 |
HOH |
2.897 |
O |
O |
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2i07 | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2006-10-24 | PHE | B:81 | B:807 | 2.0 | 0.01 | E | -131.6 | 133.4 | 2.0 | 0.01 | 0.0 | ||||||
2xwj | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2011-01-12 | PHE | B:81 | B:807 | 0.0 | 0.0 | E | -121.1 | 127.9 | 0.0 | 0.0 | 0.0 | ||||||
PHE | D:81 | D:807 | 0.0 | 0.0 | E | -121.4 | 127.9 | NA | NA | NA | |||||||||||||
PHE | F:81 | F:807 | 0.0 | 0.0 | E | -121.0 | 128.1 | NA | NA | NA | |||||||||||||
PHE | H:81 | H:807 | 0.0 | 0.0 | E | -121.2 | 127.5 | NA | NA | NA | |||||||||||||
5fo7 | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2016-04-06 | PHE | B:81 | B:829 | 4.0 | 0.019 | E | -136.0 | 128.1 | 4.0 | 0.019 | 0.0 | ||||||
5fo8 | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2016-04-06 | PHE | B:81 | B:829 | 9.0 | 0.043 | E | -128.0 | 125.8 | 9.0 | 0.043 | 0.0 | ||||||
5fo9 | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2016-04-06 | PHE | B:81 | B:829 | 5.0 | 0.024 | E | -137.5 | 128.6 | NA | NA | NA | ||||||
PHE | E:81 | E:829 | 3.0 | 0.014 | E | -138.1 | 129.8 | 3.0 | 0.014 | 0.0 | |||||||||||||
5foa | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2016-04-06 | PHE | B:81 | B:829 | 5.0 | 0.024 | E | -130.9 | 133.2 | 5.0 | 0.024 | 0.0 | ||||||
PHE | D:81 | D:829 | 5.0 | 0.024 | E | -131.5 | 134.1 | NA | NA | NA | |||||||||||||
5fob | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2016-04-06 | PHE | B:81 | B:829 | 5.0 | 0.024 | E | -130.6 | 129.2 | 5.0 | 0.024 | 0.0 |
GOL GOL HOH |
9.493 8.770 2.963 |
N CZ O |
C1 C3 O |
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6ehg | 2 | P01024 | 99.78 | 0.0 |
X-RAY |
2018-02-14 | PHE | B:81 | B:829 | 7.0 | 0.033 | E | -138.2 | 129.2 | 3.0 | 0.014 | 0.019 |
C:None:0.019 |
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6yo6 | 2 | ? | 99.78 | 0.0 |
X-RAY |
2021-02-24 | PHE | B:81 | B:829 | 6.0 | 0.029 | E | -121.6 | 129.3 | 3.0 | 0.014 | 0.015 |
C:None:0.014 |
|||||
2xwb | 2 | P01024 | 99.89 | 0.0 |
X-RAY |
2011-01-12 | PHE | B:78 | B:807 | 1.0 | 0.005 | E | -133.3 | 126.4 | 1.0 | 0.005 | 0.0 | ||||||
PHE | D:78 | D:807 | 1.0 | 0.005 | E | -134.4 | 126.3 | NA | NA | NA | |||||||||||||
2ice | 2 | P01024 | 100.0 | 2e-138 |
X-RAY |
2006-11-07 | PHE | B:81 | B:807 | 5.0 | 0.024 | E | -123.5 | 134.0 | 5.0 | 0.024 | 0.0 | ||||||
PHE | F:81 | E:807 | 4.0 | 0.019 | E | -153.2 | 127.9 | NA | NA | NA | |||||||||||||
3l3o | 2 | P01024 | 100.0 | 2e-138 |
X-RAY |
2010-08-04 | PHE | B:81 | B:807 | 1.0 | 0.005 | E | -142.4 | 140.4 | 1.0 | 0.005 | 0.0 | ||||||
PHE | H:81 | E:807 | 1.0 | 0.005 | E | -142.4 | 140.3 | NA | NA | NA | |||||||||||||
3nms | 4 | P01024 | 100.0 | 2e-138 |
X-RAY |
2010-08-04 | PHE | D:81 | B:807 | 2.0 | 0.01 | E | -150.3 | 132.7 | 2.0 | 0.01 | 0.0 | ||||||
3ohx | 2 | P01024 | 100.0 | 2e-138 |
X-RAY |
2010-09-01 | PHE | B:81 | B:807 | 1.0 | 0.005 | E | -142.4 | 140.4 | 1.0 | 0.005 | 0.0 | ||||||
PHE | D:81 | E:807 | 2.0 | 0.01 | E | -142.5 | 140.3 | NA | NA | NA | |||||||||||||
3t4a | 2 | P01024 | 100.0 | 2e-138 |
X-RAY |
2011-11-23 | PHE | B:81 | B:807 | 1.0 | 0.005 | E | -135.6 | 135.5 | 1.0 | 0.005 | 0.0 | ||||||
PHE | E:81 | E:807 | 2.0 | 0.01 | E | -135.0 | 132.2 | NA | NA | NA | |||||||||||||
2a74 | 2 | P01024 | 100.0 | 5e-125 |
X-RAY |
2005-09-27 | PHE | B:81 | B:807 | 5.0 | 0.024 | E | -127.6 | 127.9 | 5.0 | 0.024 | 0.0 |
GOL HOH |
8.721 7.916 |
CZ O |
C3 O |
||
PHE | E:81 | E:807 | 1.0 | 0.005 | E | -141.4 | 128.5 | NA | NA | NA | |||||||||||||
2qki | 2 | P01024 | 100.0 | 5e-125 |
X-RAY |
2007-08-14 | PHE | B:81 | B:807 | 7.0 | 0.033 | E | -121.6 | 120.0 | 7.0 | 0.033 | 0.0 |
GOL HOH |
9.905 3.304 |
O N |
C1 O |
||
PHE | E:81 | E:807 | 3.0 | 0.014 | E | -134.9 | 129.9 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p01024-f1 | 1 | P01024 | 100.0 | 0.0 | PHE | A:829 | A:829 | 1.0 | 0.005 | E | -137.7 | 128.5 |