Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6711125 . T A CCDS32883.1:NM_000064.2:c.1352aAc>aTc_NP_000055.2:p.451N>I Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 ASN A:429 A:429 129.0 0.806 G 53.5 49.7 129.0 0.806 0.0 HOH
 6.796
 N
 O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 ASN A:429 A:429 131.0 0.819 G 54.6 46.2 131.0 0.819 0.0
ASN C:429 C:429 129.0 0.806 G 54.6 46.1 NA NA NA
ASN E:429 E:429 133.0 0.831 G 54.6 46.1 NA NA NA
ASN G:429 G:429 130.0 0.812 G 54.7 46.1 130.0 0.812 0.0
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 ASN A:429 A:429 128.0 0.8 S 54.6 37.2 128.0 0.8 0.0
ASN C:429 C:429 128.0 0.8 S 54.7 37.1 NA NA NA
ASN E:429 E:429 127.0 0.794 S 54.8 37.0 NA NA NA
ASN G:429 G:429 128.0 0.8 S 55.0 37.0 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ASN A:429 A:429 124.0 0.775 T 55.4 38.8 124.0 0.775 0.0
ASN F:429 D:429 122.0 0.762 T 55.4 38.7 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ASN A:429 A:429 79.0 0.494 T 62.8 14.4 79.0 0.494 0.0
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 ASN A:429 A:429 122.0 0.762 T 55.4 38.7 122.0 0.762 0.0
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 ASN A:429 A:429 122.0 0.762 T 55.4 38.8 122.0 0.762 0.0
ASN H:429 D:429 122.0 0.762 T 55.3 38.8 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 ASN A:429 A:429 98.0 0.613 S 65.7 56.3 98.0 0.613 0.0
ASN D:429 D:429 114.0 0.713 S 65.7 56.3 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ASN A:429 A:451 131.0 0.819 G 52.9 39.6 131.0 0.819 0.0
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ASN A:429 A:451 129.0 0.806 G 53.3 38.5 129.0 0.806 0.0 HOH
 3.472
 OD1
 O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ASN A:429 A:451 123.0 0.769 G 54.3 39.3 NA NA NA
ASN D:429 D:451 125.0 0.781 G 54.9 38.8 125.0 0.781 0.0
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ASN A:429 A:451 130.0 0.812 S 57.3 44.9 130.0 0.812 0.0
ASN C:429 C:451 142.0 0.887 S 58.2 44.6 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 ASN A:429 A:451 138.0 0.863 G 53.9 37.0 138.0 0.863 0.0 HOH
 5.053
 ND2
 O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 ASN A:429 A:451 130.0 0.812 G 52.7 39.2 130.0 0.812 0.0
ASN F:429 E:451 125.0 0.781 G 52.8 39.5 125.0 0.781 0.0
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 ASN A:429 A:451 129.0 0.806 G 52.3 39.1 129.0 0.806 0.0
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 ASN E:429 A:429 104.0 0.65 G 54.1 49.4 104.0 0.65 0.0
ASN G:429 G:429 98.0 0.613 G 54.2 49.8 98.0 0.613 0.0
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 ASN G:429 A:429 105.0 0.656 G 51.4 45.4 105.0 0.656 0.0
ASN I:429 G:429 112.0 0.7 G 51.8 44.6 112.0 0.7 0.0
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 ASN A:429 A:429 129.0 0.806 G 54.5 47.1 129.0 0.806 0.0 HOH
 3.271
 ND2
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 ASN A:429 A:451 134.0 0.838 G 53.3 37.0 134.0 0.838 0.0
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 ASN A:429 A:429 126.0 0.787 G 47.9 51.6 126.0 0.787 0.0
ASN C:429 C:429 134.0 0.838 G 42.3 55.7 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 ASN A:429 A:451 126.0 0.787 G 56.1 41.6 126.0 0.787 0.0
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 ASN A:429 A:429 138.0 0.863 S 57.4 44.3 138.0 0.863 0.0
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 ASN A:429 A:451 118.0 0.738 G 56.1 41.5 118.0 0.738 0.0
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 ASN A:429 A:429 128.0 0.8 S 56.8 23.8 128.0 0.8 0.0
ASN C:429 C:429 126.0 0.787 S 58.4 22.4 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 ASN A:429 A:429 141.0 0.881 H 49.2 69.1 141.0 0.881 0.0
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 ASN A:429 A:429 148.0 0.925 G 65.2 24.6 148.0 0.925 0.0 HOH
 6.705
 OD1
 O
ASN D:429 D:429 141.0 0.881 S 42.3 54.7 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 ASN A:429 A:429 153.0 0.956 S 48.1 50.2 153.0 0.956 0.0 GOL
GOL
HOH
 6.758
7.525
4.295
 N
O
ND2
 O3
O1
O
ASN D:429 D:429 148.0 0.925 S 50.3 48.3 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 ASN A:429 A:429 121.0 0.756 G 59.3 29.3 121.0 0.756 0.0
ASN E:429 D:429 123.0 0.769 G 59.3 31.9 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 ASN A:429 A:429 133.0 0.831 S 30.5 72.1 133.0 0.831 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 ASN A:451 A:451 122.0 0.762 G 59.1 35.3