Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6711132 . C A CCDS32883.1:NM_000064.2:c.1345Gtg>Ttg_NP_000055.2:p.449V>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL A:427 A:427 40.0 0.258 G -66.9 114.3 40.0 0.258 0.0 HOH
 3.153
 N
 O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL A:427 A:427 23.0 0.148 G -63.7 116.3 23.0 0.148 0.0
VAL C:427 C:427 31.0 0.2 G -61.6 117.9 NA NA NA
VAL E:427 E:427 31.0 0.2 G -60.6 118.3 NA NA NA
VAL G:427 G:427 23.0 0.148 G -46.1 119.5 23.0 0.148 0.0
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 VAL A:427 A:427 37.0 0.239 T -66.5 102.0 37.0 0.239 0.0
VAL C:427 C:427 37.0 0.239 T -66.5 102.2 NA NA NA
VAL E:427 E:427 37.0 0.239 T -66.3 102.1 NA NA NA
VAL G:427 G:427 38.0 0.245 T -66.1 102.0 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:427 A:427 42.0 0.271 S -88.2 127.2 42.0 0.271 0.0
VAL F:427 D:427 41.0 0.265 S -88.3 127.2 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:427 A:427 18.0 0.116 S -62.4 138.8 18.0 0.116 0.0
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:427 A:427 40.0 0.258 S -88.2 127.2 40.0 0.258 0.0
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 VAL A:427 A:427 42.0 0.271 S -88.2 127.2 42.0 0.271 0.0
VAL H:427 D:427 42.0 0.271 S -88.1 127.1 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 VAL A:427 A:427 33.0 0.213 T -64.5 96.5 33.0 0.213 0.0
VAL D:427 D:427 32.0 0.206 T -64.6 96.5 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:427 A:449 33.0 0.213 G -75.0 106.8 33.0 0.213 0.0
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:427 A:449 56.0 0.361 G -76.6 118.3 56.0 0.361 0.0 HOH
 3.269
 N
 O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:427 A:449 42.0 0.271 G -80.7 117.3 NA NA NA
VAL D:427 D:449 32.0 0.206 G -81.3 117.9 32.0 0.206 0.0
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:427 A:449 32.0 0.206 T -65.8 101.5 32.0 0.206 0.0
VAL C:427 C:449 40.0 0.258 T -64.9 101.8 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:427 A:449 67.0 0.432 G -83.5 116.3 67.0 0.432 0.0 HOH
 3.972
 CG1
 O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL A:427 A:449 33.0 0.213 G -74.6 107.3 33.0 0.213 0.0
VAL F:427 E:449 32.0 0.206 G -74.7 107.1 32.0 0.206 0.0
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL A:427 A:449 32.0 0.206 G -75.3 106.7 32.0 0.206 0.0
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL E:427 A:427 31.0 0.2 G -69.3 114.5 31.0 0.2 0.0
VAL G:427 G:427 25.0 0.161 G -65.4 112.6 25.0 0.161 0.0
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL G:427 A:427 34.0 0.219 G -72.5 115.3 34.0 0.219 0.0
VAL I:427 G:427 39.0 0.252 G -72.4 115.7 39.0 0.252 0.0
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 VAL A:427 A:427 57.0 0.368 G -79.4 120.5 57.0 0.368 0.0 HOH
 3.217
 N
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 VAL A:427 A:449 49.0 0.316 G -69.4 123.1 49.0 0.316 0.0
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 VAL A:427 A:427 45.0 0.29 G -83.5 118.6 45.0 0.29 0.0
VAL C:427 C:427 35.0 0.226 G -84.6 125.5 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 VAL A:427 A:449 59.0 0.381 G -74.9 121.6 59.0 0.381 0.0
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 VAL A:427 A:427 29.0 0.187 T -65.5 101.2 29.0 0.187 0.0
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 VAL A:427 A:449 36.0 0.232 G -74.9 121.7 36.0 0.232 0.0
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 VAL A:427 A:427 39.0 0.252 T -72.2 98.8 39.0 0.252 0.0
VAL C:427 C:427 38.0 0.245 T -71.9 98.3 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 VAL A:427 A:427 112.0 0.723 H -62.3 121.1 112.0 0.723 0.0
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 VAL A:427 A:427 26.0 0.168 G -79.7 118.5 26.0 0.168 0.0 HOH
 3.236
 CG2
 O
VAL D:427 D:427 57.0 0.368 T -65.8 -47.1 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 VAL A:427 A:427 71.0 0.458 T -55.4 -53.2 71.0 0.458 0.0 GOL
HOH
 3.001
5.660
 N
N
 O3
O
VAL D:427 D:427 76.0 0.49 T -57.3 -51.2 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 VAL A:427 A:427 38.0 0.245 G -75.9 112.1 38.0 0.245 0.0
VAL E:427 D:427 37.0 0.239 G -76.1 109.8 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 VAL A:427 A:427 48.0 0.31 T -77.9 93.5 48.0 0.31 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 VAL A:449 A:449 58.0 0.374 G -72.4 117.8