Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6714030 . T A CCDS32883.1:NM_000064.2:c.746aAg>aTg_NP_000055.2:p.249K>M Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 LYS A:227 A:227 145.0 0.725 T -57.8 -34.2 145.0 0.725 0.0 HOH
 8.222
 N
 O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 LYS A:227 A:227 140.0 0.7 S -51.8 -44.6 140.0 0.7 0.0
LYS C:227 C:227 140.0 0.7 S -51.8 -44.6 NA NA NA
LYS E:227 E:227 140.0 0.7 S -51.9 -44.6 NA NA NA
LYS G:227 G:227 139.0 0.695 S -51.9 -44.6 139.0 0.695 0.0
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 LYS A:227 A:227 145.0 0.725 T -59.1 -30.6 145.0 0.725 0.0
LYS C:227 C:227 144.0 0.72 T -59.5 -30.2 NA NA NA
LYS E:227 E:227 147.0 0.735 T -59.4 -30.4 NA NA NA
LYS G:227 G:227 147.0 0.735 T -59.3 -30.4 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 LYS A:227 A:227 133.0 0.665 T -72.9 -17.4 133.0 0.665 0.0
LYS F:227 D:227 135.0 0.675 T -72.9 -17.5 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 LYS A:227 A:227 129.0 0.645 T -49.9 -32.5 129.0 0.645 0.0
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 LYS A:227 A:227 136.0 0.68 T -72.9 -17.4 136.0 0.68 0.0
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 LYS A:227 A:227 135.0 0.675 T -72.9 -17.4 135.0 0.675 0.0
LYS H:227 D:227 135.0 0.675 T -72.9 -17.4 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 LYS A:227 A:227 125.0 0.625 T -58.7 -21.2 125.0 0.625 0.0
LYS D:227 D:227 127.0 0.635 T -58.7 -21.1 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 LYS A:227 A:249 146.0 0.73 T -64.2 -28.3 146.0 0.73 0.0
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 LYS A:227 A:249 133.0 0.665 T -81.6 -8.6 133.0 0.665 0.0 HOH
 5.965
 NZ
 O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 LYS A:227 A:249 138.0 0.69 T -58.2 -34.1 NA NA NA
LYS D:227 D:249 140.0 0.7 T -57.5 -32.2 140.0 0.7 0.0
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 LYS A:227 A:249 158.0 0.79 S -56.8 -46.5 158.0 0.79 0.0
LYS C:227 C:249 168.0 0.84 S -57.4 -46.7 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 LYS A:227 A:249 144.0 0.72 T -64.0 -27.1 144.0 0.72 0.0 GOL
IOD
HOH
 3.253
9.045
7.075
 O
N
CB
 O3
I
O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 LYS A:227 A:249 147.0 0.735 T -64.6 -28.3 147.0 0.735 0.0
LYS F:227 E:249 147.0 0.735 T -64.7 -28.3 147.0 0.735 0.0
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 LYS A:227 A:249 141.0 0.705 T -64.1 -27.7 141.0 0.705 0.0
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 LYS E:227 A:227 126.0 0.63 S -67.2 -35.5 126.0 0.63 0.0
LYS G:227 G:227 125.0 0.625 S -65.5 -35.8 125.0 0.625 0.0
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 LYS G:227 A:227 124.0 0.62 S -70.9 -37.3 124.0 0.62 0.0
LYS I:227 G:227 121.0 0.605 S -71.0 -37.0 121.0 0.605 0.0
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 LYS A:227 A:227 151.0 0.755 T -75.7 -9.0 151.0 0.755 0.0 PEG
HOH
 5.565
2.759
 N
O
 O1
O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 LYS A:227 A:249 115.0 0.575 T -66.6 -22.5 115.0 0.575 0.0
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 LYS A:227 A:227 141.0 0.705 S -64.4 -25.0 141.0 0.705 0.0
LYS C:227 C:227 148.0 0.74 T -59.7 -26.5 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 LYS A:227 A:249 151.0 0.755 T -71.5 -10.5 151.0 0.755 0.0
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 LYS A:227 A:227 137.0 0.685 S -57.3 -47.1 137.0 0.685 0.0
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 LYS A:227 A:249 150.0 0.75 T -71.5 -10.5 150.0 0.75 0.0
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 LYS A:227 A:227 144.0 0.72 T -55.5 -37.5 144.0 0.72 0.0
LYS C:227 C:227 143.0 0.715 T -55.9 -37.2 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 LYS A:227 A:227 148.0 0.74 T -68.8 -28.4 148.0 0.74 0.0
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 LYS A:227 A:227 137.0 0.685 T -77.4 -17.3 137.0 0.685 0.0 HOH
 3.357
 C
 O
LYS D:227 D:227 120.0 0.6 T -79.7 -8.6 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 LYS A:227 A:227 144.0 0.72 T -61.0 -20.5 144.0 0.72 0.0 HOH
 3.778
 O
 O
LYS D:227 D:227 140.0 0.7 T -71.1 -15.1 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 LYS A:227 A:227 141.0 0.705 T -68.6 -10.0 141.0 0.705 0.0
LYS E:227 D:227 141.0 0.705 T -65.4 -10.8 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 LYS A:227 A:227 149.0 0.745 S -66.3 -52.7 149.0 0.745 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 LYS A:249 A:249 181.0 0.905 T -64.5 -25.1