Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7174739 . C A CCDS12176.1:NM_000208.2:c.978ttG>ttT_NP_000199.2:p.326L>F Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:299 A:299 49.0 0.288 -71.0 -9.2 49.0 0.288 0.0
LEU B:299 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:299 A:299 43.0 0.253 -92.7 31.5 43.0 0.253 0.0
LEU B:299 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 LEU A:299 A:299 9.0 0.053 -120.7 39.9 9.0 0.053 0.0
LEU B:299 C:299 11.0 0.065 -120.7 39.9 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:326 A:299 26.0 0.153 S 55.1 39.3 26.0 0.153 0.0
LEU B:326 B:299 18.0 0.106 T 55.4 38.9 18.0 0.106 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:326 A:299 10.0 0.059 S 59.5 58.4 10.0 0.059 0.0
LEU B:326 B:299 12.0 0.071 T 62.1 28.4 12.0 0.071 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:326 A:299 18.0 0.106 T 67.5 33.9 18.0 0.106 0.0
LEU B:326 B:299 36.0 0.212 T 60.3 39.4 36.0 0.212 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 LEU A:326 A:299 20.0 0.118 T 67.0 41.6 20.0 0.118 0.0
LEU B:326 B:299 32.0 0.188 T 59.7 46.3 32.0 0.188 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 LEU A:299 A:299 2.0 0.012 -96.1 26.7 2.0 0.012 0.0
LEU B:299 C:299 3.0 0.018 -96.2 26.8 3.0 0.018 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 LEU A:299 A:299 3.0 0.018 -96.1 26.7 3.0 0.018 0.0
LEU B:299 B:299 3.0 0.018 -96.2 26.8 3.0 0.018 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 LEU A:299 B:299 0.0 0.0 49.4 64.5 0.0 0.0 0.0
LEU B:299 A:299 36.0 0.212 58.3 35.7 36.0 0.212 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 LEU A:299 A:299 25.0 0.147 58.6 52.2 25.0 0.147 0.0
LEU B:299 B:299 22.0 0.129 58.6 52.2 22.0 0.129 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 LEU A:299 A:299 22.0 0.129 57.5 49.7 22.0 0.129 0.0
LEU B:299 B:299 22.0 0.129 58.6 56.3 22.0 0.129 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 LEU A:299 NA:NA DO NA DO DO DO NA NA NA
LEU B:299 F:299 8.0 0.047 T 59.5 13.4 8.0 0.047 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 LEU C:299 E:299 9.0 0.053 T 57.1 32.0 9.0 0.053 0.0
LEU D:299 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 LEU E:299 E:299 4.0 0.024 60.4 14.1 4.0 0.024 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 LEU A:299 A:299 21.0 0.124 S 71.1 43.6 21.0 0.124 0.0
LEU C:299 C:299 35.0 0.206 S 76.4 12.9 35.0 0.206 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 LEU A:299 A:299 61.0 0.359 T 60.9 61.9 61.0 0.359 0.0
LEU C:299 C:299 55.0 0.324 60.1 60.1 55.0 0.324 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 LEU E:299 E:299 4.0 0.024 57.0 14.6 4.0 0.024 0.0
LEU F:299 F:299 5.0 0.029 58.2 13.0 5.0 0.029 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 LEU A:299 A:299 4.0 0.024 53.7 15.4 4.0 0.024 0.0 HOH
 9.562
 CD1
 O
LEU B:299 B:299 3.0 0.018 69.2 7.5 3.0 0.018 0.0 HOH
 5.675
 N
 O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 LEU E:299 E:299 3.0 0.018 53.8 14.9 3.0 0.018 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 LEU B:299 E:299 7.0 0.041 53.0 15.7 7.0 0.041 0.0 NAG
 8.613
 N
 C1
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 LEU A:299 E:299 8.0 0.047 53.6 15.5 8.0 0.047 0.0
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 LEU D:299 E:299 23.0 0.135 360.0 19.0 23.0 0.135 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 LEU E:299 E:299 4.0 0.024 53.9 4.0 4.0 0.024 0.0
LEU K:299 K:299 10.0 0.059 54.4 4.4 NA NA NA
LEU Q:299 Q:299 4.0 0.024 53.4 4.9 NA NA NA
LEU W:299 W:299 12.0 0.071 55.3 3.6 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 LEU C:299 E:299 6.0 0.035 60.2 14.8 6.0 0.035 0.0
LEU G:299 K:299 4.0 0.024 60.1 14.3 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 LEU D:299 E:299 4.0 0.024 61.0 0.8 4.0 0.024 0.0
LEU I:299 K:299 4.0 0.024 63.0 1.6 NA NA NA
LEU N:299 Q:299 8.0 0.047 64.8 -9.4 NA NA NA
LEU S:299 W:299 98.0 0.576 360.0 3.8 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU E:299 E:299 0.0 0.0 55.7 10.5 0.0 0.0 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU A:299 E:299 5.0 0.029 62.3 -1.7 5.0 0.029 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 LEU A:299 E:299 4.0 0.024 61.5 -1.5 4.0 0.024 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 LEU A:326 A:326 3.0 0.018 62.4 5.0