Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184342 . G A CCDS12176.1:NM_000208.2:c.959aCg>aTg_NP_000199.2:p.320T>M Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 THR A:293 A:293 80.0 0.571 E -160.2 145.2 80.0 0.571 0.0
THR B:293 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 THR A:293 A:293 83.0 0.593 E -150.0 152.3 83.0 0.593 0.0
THR B:293 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 THR A:293 A:293 66.0 0.471 E -139.0 165.1 66.0 0.471 0.0
THR B:293 C:293 65.0 0.464 E -139.0 165.0 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 THR A:320 A:293 58.0 0.414 E -142.3 -179.7 58.0 0.414 0.0
THR B:320 B:293 30.0 0.214 E -148.5 172.5 30.0 0.214 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 THR A:320 A:293 46.0 0.329 E -74.5 133.5 46.0 0.329 0.0
THR B:320 B:293 72.0 0.514 E -96.4 143.8 72.0 0.514 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 THR A:320 A:293 65.0 0.464 E -133.4 141.4 65.0 0.464 0.0
THR B:320 B:293 48.0 0.343 E -141.8 151.5 48.0 0.343 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 THR A:320 A:293 41.0 0.293 E -100.4 151.4 41.0 0.293 0.0
THR B:320 B:293 40.0 0.286 E -90.7 162.1 40.0 0.286 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 THR A:293 A:293 59.0 0.421 E -147.2 136.9 59.0 0.421 0.0
THR B:293 C:293 61.0 0.436 E -147.3 137.1 61.0 0.436 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 THR A:293 A:293 60.0 0.429 E -147.3 137.0 60.0 0.429 0.0
THR B:293 B:293 60.0 0.429 E -147.3 137.0 60.0 0.429 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 THR A:293 B:293 56.0 0.4 -131.9 116.8 56.0 0.4 0.0
THR B:293 A:293 64.0 0.457 E -127.4 132.1 64.0 0.457 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 THR A:293 A:293 48.0 0.343 E -137.3 155.2 48.0 0.343 0.0
THR B:293 B:293 49.0 0.35 E -137.2 155.2 49.0 0.35 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 THR A:293 A:293 58.0 0.414 E -145.3 148.6 58.0 0.414 0.0
THR B:293 B:293 60.0 0.429 E -144.2 148.0 60.0 0.429 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 THR A:293 NA:NA DO NA DO DO DO NA NA NA
THR B:293 F:293 39.0 0.279 E -139.1 151.5 39.0 0.279 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 THR C:293 E:293 68.0 0.486 E -134.9 170.3 68.0 0.486 0.0
THR D:293 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 THR E:293 E:293 28.0 0.2 E -139.8 153.9 28.0 0.2 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 THR A:293 A:293 61.0 0.436 E -144.2 -167.6 61.0 0.436 0.0
THR C:293 C:293 48.0 0.343 B -146.9 -179.8 48.0 0.343 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 THR A:293 A:293 44.0 0.314 E -100.3 -178.2 44.0 0.314 0.0
THR C:293 C:293 38.0 0.271 E -100.0 -172.0 38.0 0.271 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 THR E:293 E:293 47.0 0.336 E -139.7 162.3 47.0 0.336 0.0
THR F:293 F:293 49.0 0.35 E -139.9 161.5 49.0 0.35 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 THR A:293 A:293 63.0 0.45 E -139.0 164.0 63.0 0.45 0.0
THR B:293 B:293 42.0 0.3 E -148.7 166.9 42.0 0.3 0.0 GOL
HOH
 6.195
2.642
 N
OG1
 O1
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 THR E:293 E:293 59.0 0.421 E -136.6 156.9 59.0 0.421 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 THR B:293 E:293 51.0 0.364 E -134.4 154.9 51.0 0.364 0.0 NAG
 8.111
 O
 C1
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 THR A:293 E:293 55.0 0.393 E -131.1 154.6 55.0 0.393 0.0
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 THR D:293 E:293 96.0 0.686 E -141.6 162.0 96.0 0.686 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 THR E:293 E:293 56.0 0.4 E -126.7 151.7 56.0 0.4 0.0
THR K:293 K:293 48.0 0.343 E -127.3 151.6 NA NA NA
THR Q:293 Q:293 57.0 0.407 E -128.7 152.3 NA NA NA
THR W:293 W:293 41.0 0.293 E -126.5 151.1 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 THR C:293 E:293 61.0 0.436 E -121.1 154.3 61.0 0.436 0.0
THR G:293 K:293 70.0 0.5 E -121.5 154.0 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 THR D:293 E:293 50.0 0.357 E -137.4 156.2 50.0 0.357 0.0
THR I:293 K:293 94.0 0.671 E -136.2 158.3 NA NA NA
THR N:293 Q:293 52.0 0.371 E -132.4 156.5 NA NA NA
THR S:293 W:293 126.0 0.9 -137.6 360.0 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 THR E:293 E:293 53.0 0.379 E -137.9 158.3 53.0 0.379 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 THR A:293 E:293 69.0 0.493 E -126.5 158.3 69.0 0.493 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 THR A:293 E:293 63.0 0.45 E -127.9 157.4 63.0 0.45 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 THR A:320 A:320 43.0 0.307 E -121.7 153.8