Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7184465 . C A CCDS12176.1:NM_000208.2:c.836cGc>cTc_NP_000199.2:p.279R>L Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:252 A:252 25.0 0.111 E -149.6 -167.7 25.0 0.111 0.0
ARG B:252 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:252 A:252 49.0 0.218 E -133.3 150.5 49.0 0.218 0.0
ARG B:252 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ARG A:252 A:252 29.0 0.129 E -130.1 174.9 29.0 0.129 0.0
ARG B:252 C:252 28.0 0.124 E -130.0 174.9 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:279 A:252 37.0 0.164 E -175.8 173.7 37.0 0.164 0.0
ARG B:279 B:252 66.0 0.293 E -150.9 -176.8 66.0 0.293 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:279 A:252 38.0 0.169 -161.7 -169.9 38.0 0.169 0.0
ARG B:279 B:252 40.0 0.178 E -155.7 -169.0 40.0 0.178 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:279 A:252 37.0 0.164 E -171.0 -176.4 37.0 0.164 0.0
ARG B:279 B:252 25.0 0.111 E -141.7 179.3 25.0 0.111 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ARG A:279 A:252 56.0 0.249 E -167.2 -174.9 56.0 0.249 0.0
ARG B:279 B:252 64.0 0.284 E -155.8 153.6 64.0 0.284 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:252 A:252 36.0 0.16 E -149.4 169.4 36.0 0.16 0.0
ARG B:252 C:252 34.0 0.151 E -149.4 169.3 34.0 0.151 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ARG A:252 A:252 36.0 0.16 E -149.4 169.4 36.0 0.16 0.0
ARG B:252 B:252 35.0 0.156 E -149.4 169.4 35.0 0.156 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ARG A:252 B:252 67.0 0.298 E -160.2 173.0 67.0 0.298 0.0
ARG B:252 A:252 56.0 0.249 E -154.7 -172.7 56.0 0.249 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:252 A:252 40.0 0.178 E -151.0 -175.3 40.0 0.178 0.0 NAG
FUC
 7.382
3.564
 NH1
NH1
 O6
C6
ARG B:252 B:252 39.0 0.173 E -151.1 -175.4 39.0 0.173 0.0 NAG
FUC
 7.414
3.615
 NH1
NH1
 O6
C6
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ARG A:252 A:252 40.0 0.178 E -155.7 175.2 40.0 0.178 0.0 NAG
FUC
 7.083
3.418
 NH1
NH1
 O6
C6
ARG B:252 B:252 41.0 0.182 E -158.1 175.8 41.0 0.182 0.0 NAG
FUC
 7.125
3.424
 NH1
NH1
 O6
C6
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG A:252 NA:NA DO NA DO DO DO NA NA NA
ARG B:252 F:252 57.0 0.253 E -132.5 160.4 57.0 0.253 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ARG C:252 E:252 46.0 0.204 E -137.9 151.6 46.0 0.204 0.0 NAG
 5.646
 NH1
 O6
ARG D:252 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ARG E:252 E:252 45.0 0.2 E -132.1 159.4 45.0 0.2 0.0 NAG
NAG
FUC
 7.427
9.034
3.199
 NH1
NH1
NH1
 O6
C8
C6
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ARG A:252 A:252 37.0 0.164 E -159.4 176.0 37.0 0.164 0.0
ARG C:252 C:252 44.0 0.196 -170.2 176.3 44.0 0.196 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ARG A:252 A:252 117.0 0.52 E -115.2 159.3 117.0 0.52 0.0
ARG C:252 C:252 44.0 0.196 E -143.2 160.5 44.0 0.196 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ARG E:252 E:252 41.0 0.182 E -134.5 161.9 41.0 0.182 0.0
ARG F:252 F:252 41.0 0.182 E -134.6 161.8 41.0 0.182 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ARG A:252 A:252 45.0 0.2 E -131.9 162.7 45.0 0.2 0.0 NAG
NAG
FUC
GOL
HOH
 7.223
8.371
6.263
9.621
2.952
 NH1
NH1
NH1
CB
NH1
 C6
O7
C6
C1
O
ARG B:252 B:252 46.0 0.204 E -135.2 161.4 46.0 0.204 0.0 NAG
NAG
FUC
GOL
HOH
 7.472
9.189
3.577
9.765
3.109
 NH1
NH1
NH1
CB
NH1
 O6
C8
C6
C1
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ARG E:252 E:252 42.0 0.187 E -132.3 157.8 42.0 0.187 0.0 NAG
NAG
FUC
 7.269
9.597
4.786
 NH1
NH1
NH1
 O6
C8
C6
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG B:252 E:252 44.0 0.196 E -134.6 158.4 44.0 0.196 0.0 NAG
FUC
 6.895
3.454
 NH1
NH1
 O6
C6
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ARG A:252 E:252 41.0 0.182 E -134.9 160.5 41.0 0.182 0.0 NAG
FUC
 6.931
4.322
 NH1
NH1
 O6
O2
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ARG D:252 E:252 42.0 0.187 E -132.0 158.2 42.0 0.187 0.0 NAG
NAG
FUC
 7.252
9.265
4.149
 NH1
NH1
NH1
 O6
C8
C6
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG E:252 E:252 46.0 0.204 E -131.7 166.9 46.0 0.204 0.0 NAG
NAG
FUC
HOH
 7.114
9.299
3.342
3.274
 NH1
NH1
NH1
CB
 O6
C8
C6
O
ARG K:252 K:252 48.0 0.213 E -131.2 166.7 NA NA NA
ARG Q:252 Q:252 47.0 0.209 E -132.3 167.2 NA NA NA
ARG W:252 W:252 49.0 0.218 E -130.8 167.1 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ARG C:252 E:252 43.0 0.191 E -145.9 162.9 43.0 0.191 0.0 NAG
FUC
 8.469
5.289
 NH1
NH1
 O6
C6
ARG G:252 K:252 44.0 0.196 E -146.2 162.6 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ARG D:252 E:252 47.0 0.209 E -132.3 158.9 47.0 0.209 0.0 NAG
NAG
FUC
HOH
 7.142
9.164
3.578
6.036
 NH1
NH1
NH1
O
 O6
C8
C6
O
ARG I:252 K:252 44.0 0.196 E -134.7 163.1 NA NA NA
ARG N:252 Q:252 44.0 0.196 E -135.8 162.6 NA NA NA
ARG S:252 W:252 44.0 0.196 E -134.7 160.1 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG E:252 E:252 43.0 0.191 E -134.0 156.7 43.0 0.191 0.0 NAG
NAG
 6.191
6.081
 NH1
NH1
 C6
O7
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:252 E:252 41.0 0.182 E -138.2 151.5 41.0 0.182 0.0 NAG
NAG
 6.819
6.551
 NH1
NH1
 O6
O7
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ARG A:252 E:252 41.0 0.182 E -135.7 156.2 41.0 0.182 0.0 NAG
NAG
 6.810
6.605
 NH1
NH1
 O6
O7

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ARG A:279 A:279 41.0 0.182 E -137.1 162.9