Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 7267570 . G A CCDS12176.1:NM_000208.2:c.438atC>atT_NP_000199.2:p.146I>I Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7bw7 1 P06213 100.0 0.0 EM
 2021-04-14 ILE A:119 A:119 9.0 0.051 E -135.8 120.3 9.0 0.051 0.0
ILE B:119 NA:NA DO NA DO DO DO NA NA NA
7bw8 1 P06213 100.0 0.0 EM
 2021-04-14 ILE A:119 A:119 6.0 0.034 E -114.2 113.4 6.0 0.034 0.0
ILE B:119 NA:NA DO NA DO DO DO NA NA NA
7bwa 1 P06213 100.0 0.0 EM
 2021-04-14 ILE A:119 A:119 21.0 0.12 E -134.4 138.5 21.0 0.12 0.0
ILE B:119 C:119 20.0 0.114 E -134.3 138.6 NA NA NA
7pg0 1 P06213 99.13 0.0 EM
 2022-02-02 ILE A:146 A:119 22.0 0.126 E -110.9 120.6 22.0 0.126 0.0
ILE B:146 B:119 4.0 0.023 E -95.8 89.7 4.0 0.023 0.0
7pg2 1 P06213 99.13 0.0 EM
 2022-02-02 ILE A:146 A:119 5.0 0.029 E -93.5 111.1 5.0 0.029 0.0
ILE B:146 B:119 10.0 0.057 E -130.8 96.8 10.0 0.057 0.0
7pg3 1 P06213 99.13 0.0 EM
 2022-02-02 ILE A:146 A:119 3.0 0.017 E -130.7 123.2 3.0 0.017 0.0
ILE B:146 B:119 0.0 0.0 E -131.8 96.7 0.0 0.0 0.0
7pg4 1 P06213 99.13 0.0 EM
 2022-02-02 ILE A:146 A:119 17.0 0.097 E -124.6 128.9 17.0 0.097 0.0
ILE B:146 B:119 4.0 0.023 E -108.3 94.8 4.0 0.023 0.0
6pxv 1 P06213 98.6 0.0 EM
 2019-09-04 ILE A:119 A:119 0.0 0.0 E -130.2 118.9 0.0 0.0 0.0
ILE B:119 C:119 0.0 0.0 E -130.0 118.8 0.0 0.0 0.0
6pxw 1 P06213 98.6 0.0 EM
 2019-09-04 ILE A:119 A:119 0.0 0.0 E -130.1 118.9 0.0 0.0 0.0
ILE B:119 B:119 0.0 0.0 E -130.1 118.8 0.0 0.0 0.0
6ce7 1 P06213 99.89 0.0 EM
 2018-03-14 ILE A:119 B:119 0.0 0.0 E -131.8 102.6 0.0 0.0 0.0
ILE B:119 A:119 11.0 0.063 E -112.5 126.4 11.0 0.063 0.0
6ce9 1 P06213 98.6 0.0 EM
 2018-03-14 ILE A:119 A:119 0.0 0.0 E -127.1 126.1 0.0 0.0 0.0
ILE B:119 B:119 0.0 0.0 E -127.2 126.1 0.0 0.0 0.0
6ceb 1 P06213 98.6 0.0 EM
 2018-03-14 ILE A:119 A:119 0.0 0.0 E -129.6 123.3 0.0 0.0 0.0
ILE B:119 B:119 2.0 0.011 E -127.8 126.1 2.0 0.011 0.0
6hn4 1 P06213,P03069 95.7 0.0 EM
 2018-11-21 ILE A:119 NA:NA DO NA DO DO DO NA NA NA
ILE B:119 F:119 0.0 0.0 E -126.4 105.6 0.0 0.0 0.0
6hn5 3 P06213,P03069 95.7 0.0 EM
 2018-11-21 ILE C:119 E:119 0.0 0.0 E -141.8 106.5 0.0 0.0 0.0
ILE D:119 NA:NA DO NA DO DO DO NA NA NA
4zxb 5 P06213 95.48 0.0 X-RAY
 2016-02-24 ILE E:119 E:119 0.0 0.0 E -126.9 104.9 0.0 0.0 0.0
6sof 1 P06213 100.0 0.0 EM
 2019-11-13 ILE A:119 A:119 1.0 0.006 -130.4 95.7 1.0 0.006 0.0
ILE C:119 C:119 1.0 0.006 E -114.0 133.5 1.0 0.006 0.0
7qid 1 P06213 100.0 0.0 EM
 2022-02-02 ILE A:119 A:119 21.0 0.12 E -132.2 96.3 21.0 0.12 0.0
ILE C:119 C:119 8.0 0.046 E -127.8 133.7 8.0 0.046 0.0
5kqv 5 P06213 99.83 0.0 X-RAY
 2017-07-19 ILE E:119 E:119 0.0 0.0 E -124.6 104.5 0.0 0.0 0.0
ILE F:119 F:119 0.0 0.0 E -125.0 104.2 0.0 0.0 0.0
2hr7 1 P06213 99.59 0.0 X-RAY
 2006-08-15 ILE A:119 A:119 0.0 0.0 E -123.7 103.5 0.0 0.0 0.0 P33
GOL
HOH
 9.497
9.347
5.286
 N
O
CD1
 O1
O2
O
ILE B:119 B:119 0.0 0.0 E -129.5 107.9 0.0 0.0 0.0 P33
GOL
HOH
 8.098
8.037
5.261
 N
N
O
 O7
O1
O
4oga 5 P06213 99.68 0.0 X-RAY
 2014-08-27 ILE E:119 E:119 0.0 0.0 E -124.6 100.4 0.0 0.0 0.0
4xss 2 P06213 99.68 0.0 X-RAY
 2015-06-10 ILE B:119 E:119 0.0 0.0 E -125.4 99.6 0.0 0.0 0.0
4xst 1 P06213 99.68 0.0 X-RAY
 2015-06-10 ILE A:119 E:119 0.0 0.0 E -123.8 101.4 0.0 0.0 0.0
5j3h 4 P06213 99.68 0.0 X-RAY
 2016-06-15 ILE D:119 E:119 0.0 0.0 E -127.4 105.7 0.0 0.0 0.0
6vep 5 P06213 99.68 0.0 X-RAY
 2020-06-03 ILE E:119 E:119 0.0 0.0 E -124.8 103.3 0.0 0.0 0.0
ILE K:119 K:119 0.0 0.0 E -125.6 102.2 NA NA NA
ILE Q:119 Q:119 0.0 0.0 E -124.3 103.2 NA NA NA
ILE W:119 W:119 0.0 0.0 E -127.1 102.6 NA NA NA
6veq 3 P06213 99.68 0.0 X-RAY
 2020-06-03 ILE C:119 E:119 0.0 0.0 E -127.6 104.7 0.0 0.0 0.0 SO4
 9.843
 N
 O3
ILE G:119 K:119 0.0 0.0 E -127.8 105.6 NA NA NA
7kd6 4 P06213 99.68 0.0 X-RAY
 2021-10-13 ILE D:119 E:119 0.0 0.0 E -124.4 102.2 0.0 0.0 0.0
ILE I:119 K:119 0.0 0.0 E -123.5 102.0 NA NA NA
ILE N:119 Q:119 0.0 0.0 E -123.6 100.8 NA NA NA
ILE S:119 W:119 0.0 0.0 E -121.8 102.9 NA NA NA
3w11 5 P06213 99.68 0.0 X-RAY
 2013-01-09 ILE E:119 E:119 0.0 0.0 E -124.3 99.7 0.0 0.0 0.0
3w12 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ILE A:119 E:119 0.0 0.0 E -121.9 105.9 0.0 0.0 0.0
3w13 1 P06213 99.68 0.0 X-RAY
 2013-01-09 ILE A:119 E:119 0.0 0.0 E -122.0 105.7 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06213-f1 1 P06213 100.0 0.0 ILE A:146 A:146 0.0 0.0 E -126.0 105.0