Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 8464926 . C A CCDS12201.1:NM_004218.3:c.220Cgc>Agc_NP_004209.2:p.74R>S Homo sapiens RAB11B, member RAS oncogene family (RAB11B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ojk 1 Q15907 100.0 3e-146 X-RAY
 2014-08-06 ARG A:69 A:74 110.0 NA G -54.4 -33.9 110.0 NA NA HOH
 3.466
 O
 O
ARG B:69 NA:NA DO NA DO DO DO NA NA NA
5fbl 2 P62491 91.28 1e-145 X-RAY
 2016-12-28 ARG B:79 B:74 127.0 NA 360.0 -173.1 127.0 NA NA GSP
 8.147
 N
 O3G
5fbq 2 P62491 91.28 1e-145 X-RAY
 2016-12-28 ARG B:79 B:74 136.0 NA 360.0 -173.0 136.0 NA NA
2f9l 1 Q15907 99.49 2e-145 X-RAY
 2006-04-04 ARG A:68 A:74 47.0 NA T 79.6 32.7 47.0 NA NA HOH
 3.128
 CA
 O
2f9m 1 Q15907 99.49 2e-145 X-RAY
 2006-04-04 ARG A:68 A:74 197.0 0.876 S -131.4 99.4 197.0 0.876 0.0 NI
HOH
 8.088
2.925
 O
N
 NI
O
5fbr 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ARG B:79 B:74 93.0 NA 360.0 34.6 73.0 NA NA A:Q9UBF8:NA
 GSP
 8.721
 CB
 O2G
5fbv 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ARG B:79 B:74 89.0 NA 360.0 30.9 89.0 NA NA GSP
 7.521
 CB
 S1G
5fbw 2 P62491 90.83 2e-144 X-RAY
 2016-12-28 ARG B:79 NA:NA DO NA DO DO DO NA NA NA
4d0l 2 P62491 90.83 3e-144 X-RAY
 2014-05-28 ARG B:77 B:74 50.0 0.222 H -77.8 -16.3 50.0 0.222 0.0 GSP
 9.697
 NH2
 O2G
ARG D:77 D:74 48.0 0.213 H -74.5 -19.8 NA NA NA
ARG F:77 F:74 41.0 0.182 H -74.0 -19.6 NA NA NA
4d0m 2 P62491 90.83 3e-144 X-RAY
 2014-05-28 ARG B:77 B:74 55.0 0.244 H -69.2 -20.2 55.0 0.244 0.0
ARG D:77 D:74 53.0 0.236 H -68.6 -20.4 48.0 0.213 0.023 O:Q9UBF8:0.022
ARG H:77 H:74 54.0 0.24 H -68.7 -20.2 NA NA NA
ARG J:77 J:74 55.0 0.244 H -68.4 -20.4 NA NA NA
ARG N:77 N:74 52.0 0.231 H -68.6 -20.1 NA NA NA
ARG P:77 P:74 53.0 0.236 H -68.7 -20.0 51.0 0.227 0.009 C:Q9UBF8:0.009
ARG R:77 R:74 55.0 0.244 H -68.2 -20.2 NA NA NA
ARG T:77 T:74 54.0 0.24 H -68.5 -20.2 54.0 0.24 0.0
ARG X:77 X:74 54.0 0.24 H -68.8 -20.0 NA NA NA
ARG Z:77 Z:74 53.0 0.236 H -69.0 -20.0 NA NA NA
ARG DA:77 d:74 53.0 0.236 H -68.6 -19.9 NA NA NA
ARG HA:77 h:74 54.0 0.24 H -68.8 -20.1 NA NA NA
5c46 2 P62491 90.83 3e-144 X-RAY
 2016-01-20 ARG B:77 F:74 30.0 0.133 H -50.3 -50.9 30.0 0.133 0.0 GSP
 8.792
 NH2
 O2G
5c4g 1 P62491 90.83 3e-144 X-RAY
 2016-01-20 ARG A:77 NA:NA DO NA DO DO DO NA NA NA
5euq 1 P62491 90.83 3e-144 X-RAY
 2016-02-24 ARG A:77 NA:NA DO NA DO DO DO NA NA NA
6djl 1 P62491 90.83 3e-144 X-RAY
 2018-09-26 ARG A:77 A:74 27.0 0.12 -114.5 75.0 16.0 0.071 0.049 C:O60239:0.049
ARG F:77 F:74 78.0 NA H -59.4 -45.6 NA NA NA
ARG G:77 G:74 29.0 0.129 -127.3 80.2 NA NA NA
ARG H:77 H:74 137.0 0.609 -103.4 19.3 NA NA NA
4uj4 1 P62491 95.63 9e-128 X-RAY
 2015-08-12 ARG A:73 A:74 51.0 NA -47.2 -46.0 NA NA NA
ARG D:73 NA:NA DO NA DO DO DO NA NA NA
ARG G:73 G:74 66.0 NA -162.8 142.7 51.0 NA NA I:O75154:NA
ARG J:73 NA:NA DO NA DO DO DO NA NA NA
4uj3 1 P62491 95.08 3e-127 X-RAY
 2015-08-12 ARG A:75 A:74 51.0 NA -46.9 -48.8 29.0 NA NA C:O75154:NA
 HOH
 3.768
 CB
 O
ARG D:75 NA:NA DO NA DO DO DO NA NA NA
ARG G:75 G:74 64.0 NA -162.0 141.7 NA NA NA
ARG J:75 NA:NA DO NA DO DO DO NA NA NA
ARG M:75 NA:NA DO NA DO DO DO NA NA NA
ARG P:75 NA:NA DO NA DO DO DO NA NA NA
ARG S:75 NA:NA DO NA DO DO DO NA NA NA
ARG V:75 NA:NA DO NA DO DO DO NA NA NA
5jcz 1 P62491 97.74 3e-126 X-RAY
 2016-09-28 ARG A:76 A:74 143.0 0.636 H -57.8 -34.4 143.0 0.636 0.0 EDO
HOH
 9.518
2.996
 O
N
 O2
O
ARG D:76 D:74 167.0 0.742 H -61.5 -34.2 NA NA NA
ARG F:76 NA:NA DO NA DO DO DO NA NA NA
4lwz 1 P62491 97.74 3e-126 X-RAY
 2013-11-20 ARG A:74 A:74 114.0 NA 360.0 -39.9 114.0 NA NA HOH
 7.885
 N
 O
ARG C:74 NA:NA DO NA DO DO DO NA NA NA
4lx0 1 P62491 97.74 3e-126 X-RAY
 2013-11-20 ARG A:74 A:74 46.0 0.204 S -83.3 153.4 22.0 0.098 0.106 B:Q9ULV0:0.107
 BEF
GOL
HOH
 7.610
3.042
2.628
 CG
NH1
O
 F1
O1
O
ARG C:74 C:74 49.0 0.218 S -80.6 153.0 NA NA NA
4uj5 1 P62491 94.54 8e-126 X-RAY
 2015-08-12 ARG A:73 A:74 161.0 NA 360.0 142.9 161.0 NA NA HOH
 9.150
 O
 O
ARG B:73 B:74 200.0 0.889 S -115.7 146.5 NA NA NA
4c4p 1 P62491 97.69 2e-123 X-RAY
 2013-09-18 ARG A:74 A:74 61.0 0.271 -140.3 174.6 30.0 0.133 0.138 B:Q7L804:0.138
 GNP
MG
HOH
 7.316
8.430
2.144
 HH12
HH12
HH11
 O2G
MG
O
6ixv 2 P62491 97.69 2e-123 X-RAY
 2019-03-20 ARG E:76 E:74 153.0 0.68 -82.0 -25.4 153.0 0.68 0.0
ARG F:76 F:74 235.0 1.0 S -84.5 -24.0 NA NA NA
ARG G:76 G:74 231.0 1.0 S -90.0 -29.6 NA NA NA
ARG H:76 H:74 237.0 1.0 T -77.4 -21.0 NA NA NA
1oiv 1 P24410 97.69 8e-123 X-RAY
 2004-01-08 ARG A:92 A:74 212.0 0.942 H -9.2 -70.6 210.0 0.933 0.009 B:P24410:0.009
 HOH
 3.605
 CD
 O
ARG B:92 B:74 194.0 0.862 H -32.8 -54.5 168.0 0.747 0.115 A:P24410:0.116
 HOH
 3.051
 CB
 O
2gzd 1 P62491 97.11 4e-122 X-RAY
 2006-08-15 ARG A:74 A:74 38.0 0.169 -141.8 144.7 16.0 0.071 0.098 C:Q7L804:0.098
 MG
GTP
HOH
 9.062
7.483
2.553
 NH2
NH1
O
 MG
O3G
O
ARG B:74 B:74 51.0 0.227 -106.8 158.1 26.0 0.116 0.111 D:Q7L804:0.111
 MG
GTP
HOH
 8.989
7.481
2.819
 NH1
NH1
O
 MG
O3G
O
2gzh 1 P62491 97.11 4e-122 X-RAY
 2006-08-15 ARG A:74 A:74 64.0 0.284 -147.1 178.5 31.0 0.138 0.146 B:Q7L804:0.147
 MG
GTP
HOH
 4.217
8.817
2.851
 NH1
NH1
O
 MG
O3G
O
1oiw 1 P24410 97.11 2e-121 X-RAY
 2004-01-08 ARG A:92 A:74 216.0 0.96 S -139.4 113.1 216.0 0.96 0.0 HOH
 3.365
 N
 O
1oix 1 P24410 97.11 2e-121 X-RAY
 2005-01-25 ARG A:92 A:74 220.0 0.978 S -138.6 128.1 220.0 0.978 0.0 PO4
CL
HOH
 9.996
3.716
3.299
 O
N
NE
 O2
CL
O
2hv8 1 P62491 97.06 3e-119 X-RAY
 2006-11-21 ARG A:71 A:74 40.0 0.178 -134.0 143.0 7.0 0.031 0.147 B:O75154:0.147
 MG
SO4
GTP
HOH
 8.811
6.518
7.298
2.827
 NH1
CG
NH1
O
 MG
O1
O3G
O
ARG C:71 B:74 59.0 0.262 -129.2 149.7 NA NA NA
ARG E:71 C:74 41.0 0.182 -136.3 145.3 NA NA NA
6iy1 3 P62491 97.62 4e-119 X-RAY
 2019-12-18 ARG F:69 F:74 219.0 0.973 H -61.0 -38.9 NA NA NA
1yzk 1 P62491 97.62 1e-118 X-RAY
 2005-07-26 ARG A:83 A:74 215.0 0.956 S -133.4 113.4 215.0 0.956 0.0 HOH
 3.503
 N
 O
6iy1 2 P62491 97.6 3e-118 X-RAY
 2019-12-18 ARG D:68 D:74 228.0 1.0 H -53.3 -45.1 NA NA NA
5ez5 1 P62491 97.02 4e-118 X-RAY
 2016-12-07 ARG A:67 A:74 215.0 0.956 S -131.7 109.4 215.0 0.956 0.0 HOH
 3.269
 N
 O
ARG B:67 B:74 216.0 0.96 S -134.9 105.9 216.0 0.96 0.0
2d7c 1 P62491 97.01 5e-117 X-RAY
 2006-09-26 ARG A:68 A:74 50.0 0.222 -131.6 152.4 19.0 0.084 0.138 C:O75154:0.138
 MG
GTP
HOH
 8.874
7.166
3.123
 NH2
NH2
NH2
 MG
O3G
O
ARG B:68 B:74 68.0 0.302 -96.5 155.0 NA NA NA
6iy1 1 P62491 97.58 2e-116 X-RAY
 2019-12-18 ARG A:66 A:74 219.0 0.973 H -59.3 -37.0 219.0 0.973 0.0 HOH
 7.003
 O
 O
ARG B:66 B:74 221.0 0.982 H -58.8 -37.2 NA NA NA
ARG C:66 C:74 213.0 0.947 H -57.9 -38.1 NA NA NA
ARG E:66 E:74 225.0 1.0 H -63.3 -40.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15907-f1 1 Q15907 100.0 1e-164 ARG A:74 A:74 35.0 0.156 H -57.0 -35.3
af-p62491-f1 1 P62491 91.28 6e-146 ARG A:74 A:74 60.0 0.267 H -54.7 -42.0