Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 12812416 . T A CCDS45991.1:NM_001136196.1:c.2582tAt>tTt_NP_001129668.1:p.861Y>F Homo sapiens transportin 2 (TNPO2), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2qmr 1 Q92973 84.39 0.0 X-RAY
 2007-10-30 CYS A:854 A:854 37.0 0.274 H -65.4 -47.5 37.0 0.274 0.0
CYS B:854 B:854 21.0 0.156 H -52.4 -49.1 NA NA NA
CYS C:854 C:854 21.0 0.156 H -54.6 -47.8 NA NA NA
CYS D:854 D:854 37.0 0.274 H -64.5 -48.4 NA NA NA
2z5j 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 CYS A:854 A:854 28.0 0.207 H -56.9 -29.8 28.0 0.207 0.0
2z5k 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 CYS A:854 A:854 32.0 0.237 H -74.7 -42.2 32.0 0.237 0.0 HOH
 8.342
 O
 O
2z5m 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 CYS A:854 A:854 29.0 0.215 H -62.4 -63.2 29.0 0.215 0.0
2z5n 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 CYS A:854 A:854 24.0 0.178 H -52.6 -44.0 24.0 0.178 0.0
2z5o 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 CYS A:854 A:854 27.0 0.2 H -59.4 -66.8 27.0 0.2 0.0
4fq3 1 Q92973 84.39 0.0 X-RAY
 2013-08-21 CYS A:854 A:854 29.0 0.215 H -55.4 -56.7 29.0 0.215 0.0
1qbk 1 Q92973 84.28 0.0 X-RAY
 1999-06-01 CYS A:854 B:854 29.0 0.215 H -45.6 -46.3 29.0 0.215 0.0
5yvg 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 CYS A:832 A:854 25.0 0.185 H -67.9 -36.7 25.0 0.185 0.0
CYS B:832 B:854 29.0 0.215 H -66.1 -36.6 NA NA NA
5yvh 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 CYS A:832 A:854 22.0 0.163 H -68.1 -22.1 22.0 0.163 0.0
5yvi 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 CYS A:832 A:854 32.0 0.237 H -56.2 -35.4 32.0 0.237 0.0
7cyl 1 Q92973 83.26 0.0 X-RAY
 2021-02-24 CYS A:832 A:854 27.0 0.2 H -57.9 -34.6 27.0 0.2 0.0
2h4m 1 Q92973 83.04 0.0 X-RAY
 2006-10-24 CYS A:829 A:854 37.0 0.274 H -64.2 -51.5 37.0 0.274 0.0
CYS B:829 B:854 31.0 0.23 H -56.4 -53.1 31.0 0.23 0.0
5tqc 1 Q92973 82.92 0.0 X-RAY
 2017-02-15 CYS A:830 A:854 33.0 0.244 H -68.7 -41.7 33.0 0.244 0.0
2ot8 1 Q92973 82.25 0.0 X-RAY
 2007-04-10 CYS A:816 A:854 31.0 0.23 H -47.6 -66.2 31.0 0.23 0.0
CYS B:816 B:854 37.0 0.274 H -60.2 -61.4 NA NA NA
4fdd 1 Q92973 82.25 0.0 X-RAY
 2012-07-18 CYS A:816 A:854 26.0 0.193 H -67.9 -22.0 26.0 0.193 0.0 HOH
 5.179
 O
 O
4jlq 1 Q92973 81.81 0.0 X-RAY
 2013-04-03 CYS A:818 A:854 36.0 0.267 H -59.7 -45.2 36.0 0.267 0.0
4oo6 1 Q92973 81.81 0.0 X-RAY
 2014-02-12 CYS A:818 A:854 28.0 0.207 H -45.5 -66.7 28.0 0.207 0.0
5j3v 1 Q92973 81.81 0.0 X-RAY
 2016-09-21 CYS A:818 A:854 39.0 0.289 H -66.0 -40.4 39.0 0.289 0.0
CYS C:818 B:854 29.0 0.215 H -62.5 -54.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14787-f1 1 O14787 100.0 0.0 TYR A:861 A:861 110.0 0.478 H -55.0 -49.6
af-q92973-f1 1 Q92973 84.39 0.0 CYS A:862 A:862 25.0 0.185 H -52.8 -46.6