Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 12817035 . G A CCDS45991.1:NM_001136196.1:c.1643tCt>tTt_NP_001129668.1:p.548S>F Homo sapiens transportin 2 (TNPO2), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2qmr 1 Q92973 84.39 0.0 X-RAY
2007-10-30 SER A:551 A:551 18.0 0.157 H -84.8 -39.2 18.0 0.157 0.0
SER B:551 B:551 16.0 0.139 H -78.7 -27.4 NA NA NA
SER C:551 C:551 17.0 0.148 H -79.4 -28.2 NA NA NA
SER D:551 D:551 17.0 0.148 H -85.3 -39.4 NA NA NA
2z5j 1 Q92973 84.39 0.0 X-RAY
2007-10-23 SER A:551 A:551 12.0 0.104 H -133.3 -4.6 12.0 0.104 0.0
2z5k 1 Q92973 84.39 0.0 X-RAY
2007-10-23 SER A:551 A:551 15.0 0.13 H -82.9 -40.3 15.0 0.13 0.0 PO4
HOH
7.146
9.426
O
OG
O4
O
2z5m 1 Q92973 84.39 0.0 X-RAY
2007-10-23 SER A:551 A:551 18.0 0.157 H -80.5 -49.0 18.0 0.157 0.0
2z5n 1 Q92973 84.39 0.0 X-RAY
2007-10-23 SER A:551 A:551 16.0 0.139 H -83.6 -42.5 16.0 0.139 0.0
2z5o 1 Q92973 84.39 0.0 X-RAY
2007-10-23 SER A:551 A:551 13.0 0.113 H -95.8 -57.8 13.0 0.113 0.0
4fq3 1 Q92973 84.39 0.0 X-RAY
2013-08-21 SER A:551 A:551 14.0 0.122 H -77.4 -46.2 14.0 0.122 0.0
1qbk 1 Q92973 84.28 0.0 X-RAY
1999-06-01 SER A:551 B:551 10.0 0.087 H -77.9 -54.4 10.0 0.087 0.0
5yvg 1 Q92973 83.26 0.0 X-RAY
2018-05-16 SER A:529 A:551 18.0 0.157 H -87.9 -41.4 18.0 0.157 0.0
SER B:529 B:551 33.0 0.287 H -71.0 -80.1 NA NA NA
5yvh 1 Q92973 83.26 0.0 X-RAY
2018-05-16 SER A:529 A:551 18.0 0.157 H -67.9 -45.6 18.0 0.157 0.0
5yvi 1 Q92973 83.26 0.0 X-RAY
2018-05-16 SER A:529 A:551 15.0 0.13 H -84.6 -41.6 15.0 0.13 0.0
7cyl 1 Q92973 83.26 0.0 X-RAY
2021-02-24 SER A:529 A:551 21.0 0.183 H -67.9 -45.8 21.0 0.183 0.0
2h4m 1 Q92973 83.04 0.0 X-RAY
2006-10-24 SER A:526 A:551 14.0 0.122 H -96.1 12.3 14.0 0.122 0.0
SER B:526 B:551 19.0 0.165 H -78.0 -18.3 19.0 0.165 0.0
5tqc 1 Q92973 82.92 0.0 X-RAY
2017-02-15 SER A:527 A:551 12.0 0.104 H -105.7 -45.4 12.0 0.104 0.0
2ot8 1 Q92973 82.25 0.0 X-RAY
2007-04-10 SER A:513 A:551 15.0 0.13 H -83.2 -6.1 15.0 0.13 0.0
SER B:513 B:551 21.0 0.183 H -70.5 -32.8 NA NA NA
4fdd 1 Q92973 82.25 0.0 X-RAY
2012-07-18 SER A:513 A:551 16.0 0.139 H -67.4 -45.8 16.0 0.139 0.0 HOH
2.525
OG
O
4jlq 1 Q92973 81.81 0.0 X-RAY
2013-04-03 SER A:515 A:551 14.0 0.122 H -85.3 -30.6 14.0 0.122 0.0
4oo6 1 Q92973 81.81 0.0 X-RAY
2014-02-12 SER A:515 A:551 16.0 0.139 H -85.3 -37.7 16.0 0.139 0.0
5j3v 1 Q92973 81.81 0.0 X-RAY
2016-09-21 SER A:515 A:551 15.0 0.13 H -86.4 -51.3 15.0 0.13 0.0
SER C:515 B:551 14.0 0.122 H -100.4 -46.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14787-f1 1 O14787 100.0 0.0 SER A:548 A:548 13.0 0.113 H -77.2 -39.1
af-q92973-f1 1 Q92973 84.39 0.0 SER A:559 A:559 14.0 0.122 H -67.1 -44.5