Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 12817041 . G A CCDS45991.1:NM_001136196.1:c.1637gCc>gTc_NP_001129668.1:p.546A>V Homo sapiens transportin 2 (TNPO2), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2qmr 1 Q92973 84.39 0.0 X-RAY
 2007-10-30 ALA A:549 A:549 2.0 0.017 H -58.1 -45.0 2.0 0.017 0.0
ALA B:549 B:549 1.0 0.009 H -60.0 -44.4 NA NA NA
ALA C:549 C:549 2.0 0.017 H -59.8 -45.7 NA NA NA
ALA D:549 D:549 1.0 0.009 H -56.8 -45.6 NA NA NA
2z5j 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 ALA A:549 A:549 6.0 0.052 H -55.3 -28.5 6.0 0.052 0.0
2z5k 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 ALA A:549 A:549 1.0 0.009 H -58.2 -44.6 1.0 0.009 0.0
2z5m 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 ALA A:549 A:549 1.0 0.009 H -54.8 -48.9 1.0 0.009 0.0
2z5n 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 ALA A:549 A:549 3.0 0.026 H -49.4 -50.6 3.0 0.026 0.0
2z5o 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 ALA A:549 A:549 2.0 0.017 H -64.4 -39.1 2.0 0.017 0.0
4fq3 1 Q92973 84.39 0.0 X-RAY
 2013-08-21 ALA A:549 A:549 1.0 0.009 H -58.7 -46.3 1.0 0.009 0.0
1qbk 1 Q92973 84.28 0.0 X-RAY
 1999-06-01 ALA A:549 B:549 2.0 0.017 H -69.0 -41.8 2.0 0.017 0.0
5yvg 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 ALA A:527 A:549 2.0 0.017 H -55.1 -36.5 2.0 0.017 0.0
ALA B:527 B:549 21.0 0.183 H -54.0 -46.1 NA NA NA
5yvh 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 ALA A:527 A:549 0.0 0.0 H -58.4 -42.9 0.0 0.0 0.0
5yvi 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 ALA A:527 A:549 1.0 0.009 H -68.9 -36.2 1.0 0.009 0.0
7cyl 1 Q92973 83.26 0.0 X-RAY
 2021-02-24 ALA A:527 A:549 2.0 0.017 H -58.1 -43.1 2.0 0.017 0.0
2h4m 1 Q92973 83.04 0.0 X-RAY
 2006-10-24 ALA A:524 A:549 1.0 0.009 H -36.5 -51.8 1.0 0.009 0.0
ALA B:524 B:549 2.0 0.017 H -50.0 -45.4 2.0 0.017 0.0
5tqc 1 Q92973 82.92 0.0 X-RAY
 2017-02-15 ALA A:525 A:549 3.0 0.026 H -64.1 -35.2 3.0 0.026 0.0
2ot8 1 Q92973 82.25 0.0 X-RAY
 2007-04-10 ALA A:511 A:549 1.0 0.009 H -42.4 -42.4 1.0 0.009 0.0
ALA B:511 B:549 1.0 0.009 H -51.6 -41.5 NA NA NA
4fdd 1 Q92973 82.25 0.0 X-RAY
 2012-07-18 ALA A:511 A:549 1.0 0.009 H -57.3 -42.9 1.0 0.009 0.0 HOH
 6.335
 C
 O
4jlq 1 Q92973 81.81 0.0 X-RAY
 2013-04-03 ALA A:513 A:549 1.0 0.009 H -47.8 -45.4 1.0 0.009 0.0
4oo6 1 Q92973 81.81 0.0 X-RAY
 2014-02-12 ALA A:513 A:549 1.0 0.009 H -60.0 -43.6 1.0 0.009 0.0
5j3v 1 Q92973 81.81 0.0 X-RAY
 2016-09-21 ALA A:513 A:549 1.0 0.009 H -62.3 -38.1 1.0 0.009 0.0
ALA C:513 B:549 2.0 0.017 H -70.5 -26.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14787-f1 1 O14787 100.0 0.0 ALA A:546 A:546 1.0 0.009 H -62.1 -44.2
af-q92973-f1 1 Q92973 84.39 0.0 ALA A:557 A:557 1.0 0.009 H -64.1 -41.1