Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 12821488 . G A CCDS45991.1:NM_001136196.1:c.1217cCc>cTc_NP_001129668.1:p.406P>L Homo sapiens transportin 2 (TNPO2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2qmr 1 Q92973 84.39 0.0 X-RAY
 2007-10-30 HIS A:409 A:409 161.0 0.826 S -78.7 -20.8 161.0 0.826 0.0
HIS B:409 B:409 162.0 0.831 S -81.1 -24.1 NA NA NA
HIS C:409 C:409 161.0 0.826 S -79.7 -22.0 NA NA NA
HIS D:409 D:409 162.0 0.831 S -76.3 -22.0 NA NA NA
2z5j 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 HIS A:409 A:409 186.0 0.954 S -38.1 -21.0 186.0 0.954 0.0
2z5k 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 HIS A:409 A:409 195.0 1.0 S -70.2 -36.8 195.0 1.0 0.0
2z5m 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 HIS A:409 A:409 196.0 1.0 S -74.4 -27.8 196.0 1.0 0.0
2z5n 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 HIS A:409 A:409 178.0 0.913 S -75.2 -60.1 178.0 0.913 0.0
2z5o 1 Q92973 84.39 0.0 X-RAY
 2007-10-23 HIS A:409 A:409 196.0 1.0 S -75.1 -23.0 196.0 1.0 0.0
4fq3 1 Q92973 84.39 0.0 X-RAY
 2013-08-21 HIS A:409 A:409 163.0 0.836 S -84.2 -12.8 163.0 0.836 0.0
1qbk 1 Q92973 84.28 0.0 X-RAY
 1999-06-01 HIS A:409 B:409 131.0 0.672 S 61.7 -155.3 131.0 0.672 0.0
5yvg 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 HIS A:387 A:409 170.0 0.872 S -113.8 -45.4 170.0 0.872 0.0
HIS B:387 B:409 179.0 0.918 S -111.7 -45.6 NA NA NA
5yvh 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 HIS A:387 A:409 161.0 0.826 S -84.7 -17.4 161.0 0.826 0.0
5yvi 1 Q92973 83.26 0.0 X-RAY
 2018-05-16 HIS A:387 A:409 178.0 0.913 S -78.4 -25.8 178.0 0.913 0.0
7cyl 1 Q92973 83.26 0.0 X-RAY
 2021-02-24 HIS A:387 A:409 151.0 0.774 S -84.8 -17.3 151.0 0.774 0.0
2h4m 1 Q92973 83.04 0.0 X-RAY
 2006-10-24 HIS A:384 A:409 131.0 0.672 S 36.2 -152.2 131.0 0.672 0.0
HIS B:384 B:409 92.0 0.472 S 63.2 176.1 92.0 0.472 0.0
5tqc 1 Q92973 82.92 0.0 X-RAY
 2017-02-15 HIS A:385 A:409 156.0 0.8 S -77.1 -40.4 156.0 0.8 0.0
2ot8 1 Q92973 82.25 0.0 X-RAY
 2007-04-10 HIS A:371 A:409 181.0 0.928 S -64.8 -43.7 181.0 0.928 0.0
HIS B:371 B:409 172.0 0.882 S -73.5 -42.4 NA NA NA
4fdd 1 Q92973 82.25 0.0 X-RAY
 2012-07-18 HIS A:371 A:409 168.0 0.862 S -84.3 -18.0 168.0 0.862 0.0 HOH
 2.944
 O
 O
4jlq 1 Q92973 81.81 0.0 X-RAY
 2013-04-03 HIS A:373 A:409 159.0 0.815 S -88.5 -31.1 159.0 0.815 0.0
4oo6 1 Q92973 81.81 0.0 X-RAY
 2014-02-12 HIS A:373 A:409 166.0 0.851 S -82.9 -34.8 166.0 0.851 0.0
5j3v 1 Q92973 81.81 0.0 X-RAY
 2016-09-21 HIS A:373 A:409 162.0 0.831 S -83.1 -31.4 162.0 0.831 0.0
HIS C:373 B:409 161.0 0.826 S -67.5 -33.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14787-f1 1 O14787 100.0 0.0 PRO A:406 A:406 115.0 0.793 S -71.2 -29.4
af-q92973-f1 1 Q92973 84.39 0.0 HIS A:417 A:417 155.0 0.795 S -75.7 -31.4