Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 34859491 | . | C | A | CCDS54246.1:NM_001184722.1:c.403Cga>Aga_NP_001171651.1:p.135R>R | Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1iri | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2002-06-05 | ARG | A:96 | A:96 | 64.0 | 0.284 | B | -134.1 | 155.4 | 64.0 | 0.284 | 0.0 |
E4P HOH |
8.983 2.750 |
NH1 NH1 |
O3P O |
||
| ARG | B:96 | B:96 | 73.0 | 0.324 | B | -124.7 | 144.5 | 73.0 | 0.324 | 0.0 |
E4P HOH |
9.099 6.148 |
NH2 NH2 |
O3P O |
|||||||||
| ARG | C:96 | C:96 | 66.0 | 0.293 | B | -125.6 | 152.1 | NA | NA | NA | |||||||||||||
| ARG | D:96 | D:96 | 68.0 | 0.302 | B | -124.1 | 151.5 | NA | NA | NA | |||||||||||||
| 1jiq | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2002-06-19 | ARG | A:96 | A:96 | 86.0 | 0.382 | B | -124.3 | 158.1 | 86.0 | 0.382 | 0.0 |
HOH |
2.971 |
NH1 |
O |
||
| ARG | B:96 | B:96 | 87.0 | 0.387 | B | -128.9 | 152.0 | 87.0 | 0.387 | 0.0 |
HOH |
2.898 |
NH2 |
O |
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| ARG | C:96 | C:96 | 90.0 | 0.4 | B | -131.1 | 154.3 | NA | NA | NA | |||||||||||||
| ARG | D:96 | D:96 | 91.0 | 0.404 | B | -123.3 | 159.3 | NA | NA | NA | |||||||||||||
| 1nuh | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2003-02-11 | ARG | A:96 | A:95 | 71.0 | 0.316 | B | -120.8 | 153.6 | 71.0 | 0.316 | 0.0 |
PA5 HOH |
7.727 2.727 |
NH2 NH2 |
O1 O |
||
| 1jlh | 1 | P06744 | 94.8 | 0.0 |
X-RAY |
2003-02-11 | ARG | A:96 | A:95 | 78.0 | 0.347 | B | -132.2 | 161.9 | 78.0 | 0.347 | 0.0 |
HOH |
2.756 |
NH2 |
O |
||
| ARG | B:96 | B:95 | 80.0 | 0.356 | B | -134.4 | 156.2 | 80.0 | 0.356 | 0.0 |
HOH |
2.895 |
NH1 |
O |
|||||||||
| ARG | C:96 | C:95 | 84.0 | 0.373 | B | -131.0 | 162.9 | NA | NA | NA | |||||||||||||
| ARG | D:96 | D:95 | 79.0 | 0.351 | B | -139.5 | 157.8 | NA | NA | NA | |||||||||||||
| 1iat | 1 | P06744 | 94.97 | 0.0 |
X-RAY |
2001-05-30 | ARG | A:95 | A:95 | 65.0 | 0.289 | B | -126.7 | 151.9 | 65.0 | 0.289 | 0.0 |
SO4 BME HOH |
8.855 6.764 2.776 |
NH2 NH2 NH2 |
O4 S2 O |
||
| 6xuh | 1 | P06744 | 94.96 | 0.0 |
X-RAY |
2020-07-29 | ARG | A:95 | A:95 | 61.0 | 0.271 | B | -132.3 | 152.0 | 61.0 | 0.271 | 0.0 |
PA5 HOH |
7.899 2.776 |
NH2 NH2 |
O1 O |
||
| ARG | B:95 | B:95 | 64.0 | 0.284 | B | -132.7 | 150.6 | 64.0 | 0.284 | 0.0 |
O1B HOH |
7.586 3.490 |
NH2 CA |
O O |
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| ARG | C:95 | C:95 | 61.0 | 0.271 | B | -132.8 | 151.2 | NA | NA | NA | |||||||||||||
| ARG | D:95 | D:95 | 60.0 | 0.267 | B | -132.4 | 151.2 | NA | NA | NA | |||||||||||||
| 6xui | 1 | P06744 | 94.96 | 0.0 |
X-RAY |
2020-07-29 | ARG | A:95 | A:95 | 67.0 | 0.298 | B | -127.3 | 153.3 | 67.0 | 0.298 | 0.0 |
PA5 HOH |
7.931 2.956 |
NH2 NE |
O1 O |
||
| ARG | B:95 | B:95 | 66.0 | 0.293 | B | -129.0 | 151.6 | NA | NA | NA | |||||||||||||
| ARG | C:95 | C:95 | 70.0 | 0.311 | B | -126.8 | 148.8 | NA | NA | NA | |||||||||||||
| ARG | D:95 | D:95 | 64.0 | 0.284 | B | -126.3 | 150.9 | 64.0 | 0.284 | 0.0 |
PA5 HOH |
7.920 3.087 |
NH2 NH2 |
O1A O |
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| 1gzd | 1 | P08059 | 88.51 | 0.0 |
X-RAY |
2002-06-10 | ARG | A:95 | A:95 | 74.0 | 0.329 | B | -127.9 | 159.4 | 74.0 | 0.329 | 0.0 |
SO4 HOH |
9.144 2.913 |
NH2 NH2 |
O4 O |
||
| 1gzv | 1 | P08059 | 88.51 | 0.0 |
X-RAY |
2002-10-31 | ARG | A:95 | A:95 | 72.0 | 0.32 | B | -127.2 | 162.0 | 72.0 | 0.32 | 0.0 |
PA5 |
8.559 |
NH2 |
O1 |
||
| 1g98 | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2001-06-01 | ARG | A:96 | A:95 | 73.0 | 0.324 | B | -141.6 | 159.4 | 73.0 | 0.324 | 0.0 |
PA5 HOH |
7.856 2.710 |
NH1 NH2 |
O1 O |
||
| ARG | B:96 | B:95 | 72.0 | 0.32 | B | -134.5 | 161.1 | 72.0 | 0.32 | 0.0 |
PA5 HOH |
7.746 2.765 |
NH1 NE |
O1 O |
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| 1hm5 | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2002-09-27 | ARG | A:96 | A:95 | 92.0 | 0.409 | B | -137.8 | 157.7 | 92.0 | 0.409 | 0.0 |
HOH |
2.786 |
NH2 |
O |
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| ARG | B:96 | B:95 | 77.0 | 0.342 | B | -141.7 | 158.7 | 77.0 | 0.342 | 0.0 |
HOH |
2.734 |
NH2 |
O |
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| 1hox | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2001-07-20 | ARG | A:96 | A:95 | 67.0 | 0.298 | B | -129.2 | 156.0 | 67.0 | 0.298 | 0.0 |
F6P HOH |
8.352 2.920 |
NH1 NH1 |
O3 O |
||
| ARG | B:96 | B:95 | 60.0 | 0.267 | B | -133.9 | 153.9 | 60.0 | 0.267 | 0.0 |
F6P HOH |
8.231 2.919 |
NH2 NH2 |
O3 O |
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| 1xtb | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2005-03-22 | ARG | A:96 | A:95 | 73.0 | 0.324 | B | -134.3 | 163.1 | 73.0 | 0.324 | 0.0 |
S6P HOH |
8.093 2.995 |
NH1 NH1 |
O2 O |
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| ARG | B:96 | B:1095 | 77.0 | 0.342 | B | -137.0 | 156.8 | 77.0 | 0.342 | 0.0 |
S6P HOH |
8.354 3.399 |
NH1 CA |
O2 O |
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| 1n8t | 1 | Q9N1E2 | 87.97 | 0.0 |
X-RAY |
2003-03-04 | ARG | A:95 | A:95 | 83.0 | 0.369 | B | -140.9 | 161.1 | 83.0 | 0.369 | 0.0 |
HOH |
3.407 |
NH2 |
O |
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| ARG | B:95 | B:95 | 86.0 | 0.382 | B | -139.5 | 161.5 | 86.0 | 0.382 | 0.0 |
HOH |
3.301 |
NH2 |
O |
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| 1dqr | 1 | Q9N1E2 | 87.79 | 0.0 |
X-RAY |
2000-02-09 | ARG | A:95 | A:95 | 75.0 | 0.333 | B | -117.7 | 160.9 | 75.0 | 0.333 | 0.0 |
6PG HOH |
8.044 3.556 |
NH1 NE |
O1A O |
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| ARG | B:95 | B:95 | 67.0 | 0.298 | B | -120.6 | 160.2 | 67.0 | 0.298 | 0.0 |
6PG HOH |
7.467 3.317 |
NH2 CA |
O2 O |
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| 1koj | 1 | Q9N1E2 | 87.79 | 0.0 |
X-RAY |
2002-05-03 | ARG | A:95 | A:95 | 67.0 | 0.298 | B | -133.6 | 150.6 | 67.0 | 0.298 | 0.0 |
PAN HOH |
7.857 2.864 |
NH1 NH1 |
O1 O |
||
| ARG | B:95 | B:95 | 71.0 | 0.316 | B | -136.5 | 159.9 | 71.0 | 0.316 | 0.0 |
PAN HOH |
7.457 2.955 |
NH1 NH1 |
O1 O |
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| 2cvp | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 70.0 | 0.311 | B | -132.8 | 152.6 | 70.0 | 0.311 | 0.0 |
HOH |
2.852 |
NH1 |
O |
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| ARG | B:96 | B:96 | 88.0 | 0.391 | B | -133.9 | 149.3 | 88.0 | 0.391 | 0.0 |
HOH |
3.149 |
NH1 |
O |
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| 2cxn | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 67.0 | 0.298 | B | -129.8 | 150.5 | 67.0 | 0.298 | 0.0 |
PO4 HOH |
8.934 2.858 |
NH1 NH1 |
O3 O |
||
| ARG | B:96 | B:96 | 90.0 | 0.4 | B | -130.0 | 149.7 | 90.0 | 0.4 | 0.0 |
HOH |
3.014 |
NH1 |
O |
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| 2cxo | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 70.0 | 0.311 | B | -130.9 | 151.4 | 70.0 | 0.311 | 0.0 |
DER HOH |
8.819 3.030 |
NH1 NH1 |
O3P O |
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| ARG | B:96 | B:96 | 69.0 | 0.307 | B | -127.7 | 152.2 | 69.0 | 0.307 | 0.0 |
DER HOH |
8.989 3.049 |
NH1 NH1 |
O3P O |
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| 2cxp | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 67.0 | 0.298 | B | -129.6 | 150.8 | 67.0 | 0.298 | 0.0 |
A5P HOH |
8.813 2.939 |
NH1 NH1 |
C1 O |
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| ARG | B:96 | B:96 | 71.0 | 0.316 | B | -129.3 | 149.5 | 71.0 | 0.316 | 0.0 |
A5P HOH |
8.641 2.982 |
NH1 NH1 |
C1 O |
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| 2cxq | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 68.0 | 0.302 | B | -129.3 | 150.1 | 68.0 | 0.302 | 0.0 |
S6P HOH |
7.740 2.828 |
NH1 NH1 |
O2 O |
||
| ARG | B:96 | B:96 | 73.0 | 0.324 | B | -128.4 | 150.8 | 73.0 | 0.324 | 0.0 |
S6P HOH |
7.748 3.064 |
NH1 NH1 |
O2 O |
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| 2cxr | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 69.0 | 0.307 | B | -133.2 | 150.9 | 69.0 | 0.307 | 0.0 |
6PG HOH |
7.576 2.906 |
NH1 NH1 |
O2 O |
||
| ARG | B:96 | B:96 | 70.0 | 0.311 | B | -125.8 | 151.8 | 70.0 | 0.311 | 0.0 |
6PG HOH |
7.607 2.869 |
NH1 NH1 |
O2 O |
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| 2cxs | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 67.0 | 0.298 | B | -127.8 | 149.3 | 67.0 | 0.298 | 0.0 |
F6P HOH |
8.571 2.831 |
NH1 NH1 |
O2 O |
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| ARG | B:96 | B:96 | 72.0 | 0.32 | B | -128.3 | 150.1 | 72.0 | 0.32 | 0.0 |
F6P HOH |
8.629 2.994 |
NH1 NH1 |
O2 O |
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| 2cxt | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 66.0 | 0.293 | B | -129.2 | 147.9 | 66.0 | 0.293 | 0.0 |
F6P HOH |
8.740 2.894 |
NH1 NH2 |
O2 O |
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| ARG | B:96 | B:96 | 70.0 | 0.311 | B | -131.0 | 149.0 | 70.0 | 0.311 | 0.0 |
F6P HOH |
8.625 3.065 |
NH1 NE |
O2 O |
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| 2cxu | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | ARG | A:96 | A:96 | 67.0 | 0.298 | B | -129.0 | 150.7 | 67.0 | 0.298 | 0.0 |
PO4 HOH |
8.913 2.898 |
NH1 NH1 |
O3 O |
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| ARG | B:96 | B:96 | 89.0 | 0.396 | B | -130.7 | 150.9 | 89.0 | 0.396 | 0.0 |
HOH |
3.026 |
NH1 |
O |
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| 1u0e | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | ARG | A:96 | A:95 | 67.0 | 0.298 | B | -135.8 | 149.5 | 67.0 | 0.298 | 0.0 |
SO4 HOH |
9.105 2.930 |
NH1 NH1 |
O1 O |
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| ARG | B:96 | B:95 | 86.0 | 0.382 | B | -137.6 | 148.6 | 86.0 | 0.382 | 0.0 |
SO4 SO4 HOH |
9.052 9.151 2.968 |
NH1 NH2 NH1 |
O4 O1 O |
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| 1u0f | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | ARG | A:96 | A:95 | 71.0 | 0.316 | B | -130.1 | 152.2 | 71.0 | 0.316 | 0.0 |
G6P G6Q GOL HOH |
8.758 7.613 6.916 2.970 |
NH1 NH1 N NH1 |
O3 O2 O1 O |
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| ARG | B:96 | B:95 | 76.0 | 0.338 | B | -134.8 | 149.6 | 76.0 | 0.338 | 0.0 |
SO4 SO4 HOH |
9.419 8.961 2.883 |
NH1 NH1 NH1 |
O4 O4 O |
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| 1u0g | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | ARG | A:96 | A:95 | 69.0 | 0.307 | B | -129.7 | 152.8 | 69.0 | 0.307 | 0.0 |
E4P HOH |
8.766 2.951 |
NH1 NH1 |
O3P O |
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| ARG | B:96 | B:95 | 71.0 | 0.316 | B | -127.3 | 152.3 | 71.0 | 0.316 | 0.0 |
E4P BME HOH |
8.826 7.173 2.996 |
NH1 O NH1 |
O3P C1 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06744-f1 | 1 | P06744 | 94.98 | 0.0 | ARG | A:96 | A:96 | 70.0 | 0.311 | B | -117.0 | 149.2 | |