Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 34887521 . G A CCDS54246.1:NM_001184722.1:c.1261Gtc>Atc_NP_001171651.1:p.421V>I Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1iri 1 P06744 94.98 0.0 X-RAY
 2002-06-05 VAL A:410 A:410 69.0 0.445 E -70.5 -36.6 5.0 0.032 0.413 B:P06744:0.413
 HOH
 2.795
 O
 O
VAL B:410 B:410 71.0 0.458 E -63.2 -41.6 7.0 0.045 0.413 A:P06744:0.413
 HOH
 4.198
 O
 O
VAL C:410 C:410 70.0 0.452 E -68.7 -42.7 NA NA NA
VAL D:410 D:410 71.0 0.458 E -65.1 -42.8 NA NA NA
1jiq 1 P06744 94.98 0.0 X-RAY
 2002-06-19 VAL A:410 A:410 71.0 0.458 E -65.6 -43.2 5.0 0.032 0.426 B:P06744:0.426
 HOH
 2.767
 O
 O
VAL B:410 B:410 71.0 0.458 E -62.2 -46.0 7.0 0.045 0.413 A:P06744:0.413
 HOH
 2.832
 O
 O
VAL C:410 C:410 73.0 0.471 E -66.3 -43.3 NA NA NA
VAL D:410 D:410 71.0 0.458 E -63.1 -45.1 NA NA NA
1nuh 1 P06744 94.98 0.0 X-RAY
 2003-02-11 VAL A:410 A:409 71.0 0.458 E -74.6 -38.2 8.0 0.052 0.406 A:P06744:0.406
 HOH
 6.258
 N
 O
1jlh 1 P06744 94.8 0.0 X-RAY
 2003-02-11 VAL A:410 A:409 72.0 0.465 E -67.8 -43.5 6.0 0.039 0.426 B:P06744:0.426
 HOH
 2.739
 O
 O
VAL B:410 B:409 72.0 0.465 E -65.2 -42.9 8.0 0.052 0.413 A:P06744:0.413
 HOH
 2.704
 O
 O
VAL C:410 C:409 73.0 0.471 E -68.6 -43.0 NA NA NA
VAL D:410 D:409 71.0 0.458 E -65.2 -42.2 NA NA NA
1iat 1 P06744 94.97 0.0 X-RAY
 2001-05-30 VAL A:409 A:409 73.0 0.471 E -65.5 -44.0 8.0 0.052 0.419 A:P06744:0.419
 HOH
 2.741
 O
 O
6xuh 1 P06744 94.96 0.0 X-RAY
 2020-07-29 VAL A:409 A:409 71.0 0.458 E -71.8 -41.9 7.0 0.045 0.413 B:P06744:0.413
 HOH
 3.222
 O
 O
VAL B:409 B:409 72.0 0.465 E -72.0 -42.1 8.0 0.052 0.413 A:P06744:0.413
 HOH
 5.774
 N
 O
VAL C:409 C:409 72.0 0.465 E -72.4 -42.0 NA NA NA
VAL D:409 D:409 72.0 0.465 E -72.4 -41.9 NA NA NA
6xui 1 P06744 94.96 0.0 X-RAY
 2020-07-29 VAL A:409 A:409 73.0 0.471 E -65.6 -45.6 5.0 0.032 0.439 D:P06744:0.439
 HOH
 2.775
 O
 O
VAL B:409 B:409 73.0 0.471 E -67.4 -43.8 NA NA NA
VAL C:409 C:409 72.0 0.465 E -65.6 -44.7 NA NA NA
VAL D:409 D:409 75.0 0.484 E -70.4 -42.8 7.0 0.045 0.439 A:P06744:0.439
 HOH
 2.690
 O
 O
1gzd 1 P08059 88.51 0.0 X-RAY
 2002-06-10 VAL A:409 A:409 71.0 0.458 E -76.8 -34.3 5.0 0.032 0.426 A:P08059:0.426
 HOH
 4.024
 O
 O
1gzv 1 P08059 88.51 0.0 X-RAY
 2002-10-31 VAL A:409 A:409 69.0 0.445 E -80.0 -31.9 6.0 0.039 0.406 A:P08059:0.406
1g98 1 Q9N1E2 87.81 0.0 X-RAY
 2001-06-01 VAL A:410 A:409 72.0 0.465 E -64.5 -45.6 7.0 0.045 0.42 B:Q9N1E2:0.419
 HOH
 2.707
 O
 O
VAL B:410 B:409 72.0 0.465 E -64.9 -44.5 7.0 0.045 0.42 A:Q9N1E2:0.419
 HOH
 2.643
 O
 O
1hm5 1 Q9N1E2 87.81 0.0 X-RAY
 2002-09-27 VAL A:410 A:409 74.0 0.477 E -64.9 -45.8 6.0 0.039 0.438 B:Q9N1E2:0.439
 HOH
 2.801
 O
 O
VAL B:410 B:409 73.0 0.471 E -64.8 -44.3 5.0 0.032 0.439 A:Q9N1E2:0.439
 HOH
 2.753
 O
 O
1hox 1 Q9N1E2 87.81 0.0 X-RAY
 2001-07-20 VAL A:410 A:409 70.0 0.452 E -72.1 -42.6 6.0 0.039 0.413 B:Q9N1E2:0.413
 HOH
 2.635
 O
 O
VAL B:410 B:409 70.0 0.452 E -68.0 -45.5 7.0 0.045 0.407 A:Q9N1E2:0.406
 HOH
 2.922
 O
 O
1xtb 1 Q9N1E2 87.81 0.0 X-RAY
 2005-03-22 VAL A:410 A:409 73.0 0.471 E -63.7 -42.6 8.0 0.052 0.419 B:Q9N1E2:0.419
 HOH
 2.826
 O
 O
VAL B:410 B:1409 72.0 0.465 E -63.0 -45.1 7.0 0.045 0.42 A:Q9N1E2:0.419
 HOH
 2.778
 O
 O
1n8t 1 Q9N1E2 87.97 0.0 X-RAY
 2003-03-04 VAL A:409 A:409 73.0 0.471 E -57.6 -50.9 5.0 0.032 0.439 B:Q9N1E2:0.439
 HOH
 2.812
 O
 O
VAL B:409 B:409 73.0 0.471 E -60.3 -46.4 6.0 0.039 0.432 A:Q9N1E2:0.432
 HOH
 3.096
 O
 O
1dqr 1 Q9N1E2 87.79 0.0 X-RAY
 2000-02-09 VAL A:409 A:409 71.0 0.458 E -63.2 -46.2 3.0 0.019 0.439 B:Q9N1E2:0.439
 HOH
 5.566
 O
 O
VAL B:409 B:409 69.0 0.445 E -62.9 -45.4 5.0 0.032 0.413 A:Q9N1E2:0.413
 HOH
 4.817
 O
 O
1koj 1 Q9N1E2 87.79 0.0 X-RAY
 2002-05-03 VAL A:409 A:409 73.0 0.471 E -66.9 -43.3 9.0 0.058 0.413 B:Q9N1E2:0.413
 HOH
 2.554
 CG1
 O
VAL B:409 B:409 72.0 0.465 E -67.9 -46.5 5.0 0.032 0.433 A:Q9N1E2:0.432
 HOH
 2.651
 O
 O
2cvp 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 73.0 0.471 E -63.9 -47.0 5.0 0.032 0.439 B:P06745:0.439
 GOL
HOH
 5.342
2.685
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -67.4 -44.5 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.210
2.730
 O
O
 O3
O
2cxn 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 74.0 0.477 E -63.3 -46.5 5.0 0.032 0.445 B:P06745:0.445
 GOL
HOH
 5.314
2.776
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -63.5 -45.6 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.257
2.845
 O
O
 O3
O
2cxo 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 72.0 0.465 E -63.6 -46.8 4.0 0.026 0.439 B:P06745:0.439
 GOL
HOH
 5.342
2.864
 O
O
 O3
O
VAL B:410 B:410 73.0 0.471 E -64.3 -45.0 4.0 0.026 0.445 A:P06745:0.445
 GOL
HOH
 5.194
2.797
 O
O
 O3
O
2cxp 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 75.0 0.484 E -64.0 -46.2 4.0 0.026 0.458 B:P06745:0.458
 GOL
HOH
 5.244
2.732
 O
O
 O3
O
VAL B:410 B:410 73.0 0.471 E -62.4 -45.3 4.0 0.026 0.445 A:P06745:0.445
 GOL
HOH
 5.197
2.798
 O
O
 O3
O
2cxq 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 74.0 0.477 E -65.0 -45.3 5.0 0.032 0.445 B:P06745:0.445
 GOL
HOH
 5.232
2.728
 O
O
 O3
O
VAL B:410 B:410 73.0 0.471 E -63.3 -45.5 4.0 0.026 0.445 A:P06745:0.445
 GOL
HOH
 5.224
2.820
 O
O
 O3
O
2cxr 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 74.0 0.477 E -64.9 -45.7 4.0 0.026 0.451 B:P06745:0.452
 GOL
HOH
 5.246
2.720
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -62.1 -45.2 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.182
2.766
 O
O
 O3
O
2cxs 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 74.0 0.477 E -64.5 -45.2 5.0 0.032 0.445 B:P06745:0.445
 GOL
HOH
 5.174
2.708
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -64.5 -45.6 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.229
2.808
 O
O
 O3
O
2cxt 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 75.0 0.484 E -65.9 -42.3 5.0 0.032 0.452 B:P06745:0.452
 GOL
HOH
 5.190
2.656
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -65.9 -42.8 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.144
2.822
 O
O
 O3
O
2cxu 1 P06745 84.38 0.0 X-RAY
 2006-05-23 VAL A:410 A:410 74.0 0.477 E -63.6 -45.3 5.0 0.032 0.445 B:P06745:0.445
 GOL
HOH
 5.219
2.709
 O
O
 O3
O
VAL B:410 B:410 74.0 0.477 E -64.1 -44.6 4.0 0.026 0.451 A:P06745:0.452
 GOL
HOH
 5.162
2.720
 O
O
 O3
O
1u0e 1 P06745 84.05 0.0 X-RAY
 2004-11-02 VAL A:410 A:409 73.0 0.471 E -65.2 -46.3 5.0 0.032 0.439 B:P06745:0.439
 BME
HOH
 5.348
2.813
 O
O
 O1
O
VAL B:410 B:409 74.0 0.477 E -67.6 -43.4 6.0 0.039 0.438 A:P06745:0.439
 HOH
 2.662
 O
 O
1u0f 1 P06745 84.05 0.0 X-RAY
 2004-11-02 VAL A:410 A:409 73.0 0.471 E -64.3 -47.9 5.0 0.032 0.439 B:P06745:0.439
 SO4
BME
HOH
 9.848
5.322
2.832
 CG2
O
O
 O1
O1
O
VAL B:410 B:409 73.0 0.471 E -67.5 -42.4 7.0 0.045 0.426 A:P06745:0.426
 GOL
HOH
 5.011
2.722
 O
O
 O1
O
1u0g 1 P06745 84.05 0.0 X-RAY
 2004-11-02 VAL A:410 A:409 72.0 0.465 E -66.6 -45.9 4.0 0.026 0.439 B:P06745:0.439
 BME
HOH
 5.295
2.744
 O
O
 O1
O
VAL B:410 B:409 72.0 0.465 E -66.5 -44.6 5.0 0.032 0.433 A:P06745:0.432
 HOH
 2.763
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p06744-f1 1 P06744 94.98 0.0 VAL A:410 A:410 74.0 0.477 E -64.3 -43.5