Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 34887546 | . | A | C | CCDS54246.1:NM_001184722.1:c.1286aAg>aCg_NP_001171651.1:p.429K>T | Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1iri | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2002-06-05 | LYS | A:418 | A:418 | 212.0 | 1.0 | G | 55.5 | 40.4 | 212.0 | 1.0 | 0.0 |
HOH |
4.753 |
C |
O |
||
| LYS | B:418 | B:418 | 220.0 | 1.0 | H | 53.8 | 37.2 | 220.0 | 1.0 | 0.0 |
HOH |
3.399 |
CA |
O |
|||||||||
| LYS | C:418 | C:418 | 218.0 | 1.0 | H | 57.4 | 41.7 | NA | NA | NA | |||||||||||||
| LYS | D:418 | D:418 | 213.0 | 1.0 | G | 78.4 | 35.6 | NA | NA | NA | |||||||||||||
| 1jiq | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2002-06-19 | LYS | A:418 | A:418 | 214.0 | 1.0 | H | 53.1 | 37.9 | 214.0 | 1.0 | 0.0 |
HOH |
2.758 |
N |
O |
||
| LYS | B:418 | B:418 | 214.0 | 1.0 | G | 53.1 | 35.7 | 214.0 | 1.0 | 0.0 |
HOH |
2.915 |
N |
O |
|||||||||
| LYS | C:418 | C:418 | 217.0 | 1.0 | G | 52.8 | 31.8 | NA | NA | NA | |||||||||||||
| LYS | D:418 | D:418 | 211.0 | 1.0 | G | 68.7 | 31.8 | NA | NA | NA | |||||||||||||
| 1nuh | 1 | P06744 | 94.98 | 0.0 |
X-RAY |
2003-02-11 | LYS | A:418 | A:417 | 212.0 | 1.0 | G | 49.6 | 36.8 | 212.0 | 1.0 | 0.0 |
HOH |
7.844 |
C |
O |
||
| 1jlh | 1 | P06744 | 94.8 | 0.0 |
X-RAY |
2003-02-11 | LYS | A:418 | A:417 | 202.0 | 1.0 | H | 50.5 | 34.7 | 196.0 | 0.98 | 0.02 |
B:P06744:0.03 |
HOH |
2.783 |
N |
O |
|
| LYS | B:418 | B:417 | 205.0 | 1.0 | G | 63.0 | 32.0 | 205.0 | 1.0 | 0.0 |
HOH |
2.753 |
N |
O |
|||||||||
| LYS | C:418 | C:417 | 208.0 | 1.0 | G | 51.2 | 39.9 | NA | NA | NA | |||||||||||||
| LYS | D:418 | D:417 | 204.0 | 1.0 | H | 55.4 | 38.4 | NA | NA | NA | |||||||||||||
| 1iat | 1 | P06744 | 94.97 | 0.0 |
X-RAY |
2001-05-30 | LYS | A:417 | A:417 | 209.0 | 1.0 | H | 53.7 | 34.3 | 209.0 | 1.0 | 0.0 |
HOH |
2.806 |
N |
O |
||
| 6xuh | 1 | P06744 | 94.96 | 0.0 |
X-RAY |
2020-07-29 | LYS | A:417 | A:417 | 213.0 | 1.0 | H | 51.4 | 44.5 | 213.0 | 1.0 | 0.0 |
HOH |
5.089 |
N |
O |
||
| LYS | B:417 | B:417 | 214.0 | 1.0 | H | 51.2 | 44.2 | 214.0 | 1.0 | 0.0 |
HOH |
5.193 |
N |
O |
|||||||||
| LYS | C:417 | C:417 | 213.0 | 1.0 | H | 51.1 | 44.3 | NA | NA | NA | |||||||||||||
| LYS | D:417 | D:417 | 213.0 | 1.0 | H | 51.2 | 44.3 | NA | NA | NA | |||||||||||||
| 6xui | 1 | P06744 | 94.96 | 0.0 |
X-RAY |
2020-07-29 | LYS | A:417 | A:417 | 216.0 | 1.0 | G | 57.9 | 39.9 | 216.0 | 1.0 | 0.0 |
HOH |
2.741 |
N |
O |
||
| LYS | B:417 | B:417 | 212.0 | 1.0 | G | 54.3 | 37.8 | NA | NA | NA | |||||||||||||
| LYS | C:417 | C:417 | 218.0 | 1.0 | H | 51.4 | 39.3 | NA | NA | NA | |||||||||||||
| LYS | D:417 | D:417 | 211.0 | 1.0 | G | 53.9 | 37.5 | 211.0 | 1.0 | 0.0 |
HOH |
2.794 |
O |
O |
|||||||||
| 1gzd | 1 | P08059 | 88.51 | 0.0 |
X-RAY |
2002-06-10 | LYS | A:417 | A:417 | 222.0 | 1.0 | H | 49.6 | 42.5 | 222.0 | 1.0 | 0.0 |
HOH |
2.813 |
N |
O |
||
| 1gzv | 1 | P08059 | 88.51 | 0.0 |
X-RAY |
2002-10-31 | LYS | A:417 | A:417 | 212.0 | 1.0 | H | 48.9 | 50.4 | 212.0 | 1.0 | 0.0 | ||||||
| 1g98 | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2001-06-01 | LYS | A:418 | A:417 | 182.0 | 0.91 | G | 55.4 | 36.1 | 182.0 | 0.91 | 0.0 |
HOH |
3.577 |
NZ |
O |
||
| LYS | B:418 | B:417 | 212.0 | 1.0 | G | 58.8 | 33.0 | 212.0 | 1.0 | 0.0 |
HOH |
2.730 |
N |
O |
|||||||||
| 1hm5 | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2002-09-27 | LYS | A:418 | A:417 | 213.0 | 1.0 | G | 56.6 | 28.0 | 213.0 | 1.0 | 0.0 |
HOH |
2.969 |
N |
O |
||
| LYS | B:418 | B:417 | 215.0 | 1.0 | G | 54.5 | 37.1 | 215.0 | 1.0 | 0.0 |
HOH |
2.759 |
N |
O |
|||||||||
| 1hox | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2001-07-20 | LYS | A:418 | A:417 | 216.0 | 1.0 | G | 55.2 | 35.7 | 216.0 | 1.0 | 0.0 |
HOH |
3.096 |
CA |
O |
||
| LYS | B:418 | B:417 | 213.0 | 1.0 | G | 61.0 | 33.6 | 213.0 | 1.0 | 0.0 |
HOH |
2.733 |
NZ |
O |
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| 1xtb | 1 | Q9N1E2 | 87.81 | 0.0 |
X-RAY |
2005-03-22 | LYS | A:418 | A:417 | 214.0 | 1.0 | G | 56.0 | 35.3 | 214.0 | 1.0 | 0.0 |
HOH |
2.819 |
N |
O |
||
| LYS | B:418 | B:1417 | 213.0 | 1.0 | G | 54.7 | 41.4 | 213.0 | 1.0 | 0.0 |
HOH |
4.151 |
O |
O |
|||||||||
| 1n8t | 1 | Q9N1E2 | 87.97 | 0.0 |
X-RAY |
2003-03-04 | LYS | A:417 | A:417 | 219.0 | 1.0 | G | 55.6 | 29.8 | 219.0 | 1.0 | 0.0 |
HOH |
4.667 |
O |
O |
||
| LYS | B:417 | B:417 | 193.0 | 0.965 | G | 55.7 | 31.2 | 193.0 | 0.965 | 0.0 |
HOH |
5.025 |
N |
O |
|||||||||
| 1dqr | 1 | Q9N1E2 | 87.79 | 0.0 |
X-RAY |
2000-02-09 | LYS | A:417 | A:417 | 211.0 | 1.0 | G | 57.0 | 36.7 | 211.0 | 1.0 | 0.0 |
HOH |
3.405 |
O |
O |
||
| LYS | B:417 | B:417 | 205.0 | 1.0 | G | 59.8 | 32.5 | 205.0 | 1.0 | 0.0 |
HOH |
3.600 |
O |
O |
|||||||||
| 1koj | 1 | Q9N1E2 | 87.79 | 0.0 |
X-RAY |
2002-05-03 | LYS | A:417 | A:417 | 217.0 | 1.0 | G | 56.8 | 33.9 | 217.0 | 1.0 | 0.0 |
HOH |
2.813 |
O |
O |
||
| LYS | B:417 | B:417 | 211.0 | 1.0 | G | 56.3 | 32.9 | 211.0 | 1.0 | 0.0 |
HOH |
2.703 |
O |
O |
|||||||||
| 2cvp | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 219.0 | 1.0 | G | 54.0 | 32.7 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.787 2.836 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 220.0 | 1.0 | G | 57.3 | 29.1 | 220.0 | 1.0 | 0.0 |
GOL HOH |
4.659 2.864 |
O N |
C1 O |
|||||||||
| 2cxn | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 218.0 | 1.0 | G | 52.5 | 35.3 | 216.0 | 1.0 | 0.0 |
B:P06745:0.01 |
GOL HOH |
4.728 2.973 |
O N |
C1 O |
|
| LYS | B:418 | B:418 | 218.0 | 1.0 | H | 56.8 | 31.5 | 218.0 | 1.0 | 0.0 |
GOL HOH |
4.657 2.781 |
O O |
C1 O |
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| 2cxo | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 216.0 | 1.0 | G | 55.0 | 30.3 | 216.0 | 1.0 | 0.0 |
GOL HOH |
4.653 2.911 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 216.0 | 1.0 | H | 54.0 | 34.8 | 216.0 | 1.0 | 0.0 |
GOL HOH |
4.745 2.892 |
O N |
C1 O |
|||||||||
| 2cxp | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 219.0 | 1.0 | G | 52.4 | 33.0 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.731 2.775 |
O NZ |
C1 O |
||
| LYS | B:418 | B:418 | 219.0 | 1.0 | H | 54.7 | 33.5 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.730 2.696 |
O O |
C1 O |
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| 2cxq | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 213.0 | 1.0 | G | 54.0 | 33.6 | 213.0 | 1.0 | 0.0 |
GOL HOH |
4.678 2.885 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 219.0 | 1.0 | H | 54.3 | 34.8 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.703 2.897 |
O N |
C1 O |
|||||||||
| 2cxr | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 213.0 | 1.0 | G | 56.3 | 31.4 | 213.0 | 1.0 | 0.0 |
GOL HOH |
4.638 2.893 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 214.0 | 1.0 | H | 54.7 | 35.7 | 214.0 | 1.0 | 0.0 |
GOL HOH |
4.726 2.892 |
O N |
C1 O |
|||||||||
| 2cxs | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 217.0 | 1.0 | G | 53.5 | 33.0 | 217.0 | 1.0 | 0.0 |
GOL HOH |
4.687 2.880 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 219.0 | 1.0 | H | 54.1 | 32.9 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.705 2.917 |
O N |
C1 O |
|||||||||
| 2cxt | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 219.0 | 1.0 | G | 54.8 | 30.7 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.697 2.866 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 217.0 | 1.0 | H | 55.1 | 30.1 | 217.0 | 1.0 | 0.0 |
GOL HOH |
4.745 2.940 |
O N |
C1 O |
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| 2cxu | 1 | P06745 | 84.38 | 0.0 |
X-RAY |
2006-05-23 | LYS | A:418 | A:418 | 219.0 | 1.0 | G | 53.8 | 31.9 | 219.0 | 1.0 | 0.0 |
GOL HOH |
4.913 2.826 |
O N |
C1 O |
||
| LYS | B:418 | B:418 | 217.0 | 1.0 | H | 54.2 | 33.1 | 217.0 | 1.0 | 0.0 |
GOL HOH |
4.692 2.916 |
O N |
C1 O |
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| 1u0e | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | LYS | A:418 | A:417 | 216.0 | 1.0 | G | 52.9 | 34.1 | 216.0 | 1.0 | 0.0 |
BME HOH |
5.283 2.735 |
O N |
S2 O |
||
| LYS | B:418 | B:417 | 217.0 | 1.0 | H | 53.6 | 38.6 | 217.0 | 1.0 | 0.0 |
HOH |
2.691 |
N |
O |
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| 1u0f | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | LYS | A:418 | A:417 | 216.0 | 1.0 | G | 54.0 | 31.8 | 216.0 | 1.0 | 0.0 |
BME GOL HOH |
5.239 7.016 2.898 |
O N N |
S2 O3 O |
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| LYS | B:418 | B:417 | 215.0 | 1.0 | H | 48.5 | 35.6 | 215.0 | 1.0 | 0.0 |
GOL GOL HOH |
5.321 6.986 2.827 |
O N N |
C1 O3 O |
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| 1u0g | 1 | P06745 | 84.05 | 0.0 |
X-RAY |
2004-11-02 | LYS | A:418 | A:417 | 218.0 | 1.0 | G | 53.1 | 33.6 | 218.0 | 1.0 | 0.0 |
BME HOH |
5.263 2.815 |
O N |
S2 O |
||
| LYS | B:418 | B:417 | 220.0 | 1.0 | H | 50.6 | 37.5 | 220.0 | 1.0 | 0.0 |
GOL HOH |
7.220 2.869 |
N N |
O3 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p06744-f1 | 1 | P06744 | 94.98 | 0.0 | LYS | A:418 | A:418 | 219.0 | 1.0 | G | 55.3 | 40.1 | |