Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41836966 . C A CCDS33031.1:NM_000660.4:c.1164aaG>aaT_NP_000651.3:p.388K>N Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 LYS C:361 C:359 78.0 0.39 E -124.6 175.3 36.0 0.18 0.21 D:P01137:0.21
LYS D:361 D:359 78.0 0.39 E -127.0 171.8 42.0 0.21 0.18 C:P01137:0.18
LYS G:361 G:359 79.0 0.395 E -125.1 175.0 38.0 0.19 0.205 H:P01137:0.205
LYS H:361 H:359 78.0 0.39 E -126.9 172.0 41.0 0.205 0.185 G:P01137:0.185
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 LYS A:361 A:359 98.0 0.49 E -161.6 162.2 76.0 0.38 0.11 A:P01137:0.11
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 LYS C:361 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 LYS A:361 A:359 26.0 0.13 E -141.4 159.2 4.0 0.02 0.11 B:P07200:0.11
LYS B:361 B:359 76.0 0.38 E -141.6 159.2 42.0 0.21 0.17 A:P07200:0.17
LYS C:361 C:359 27.0 0.135 E -141.3 158.7 NA NA NA
LYS D:361 D:359 75.0 0.375 E -141.3 158.5 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 LYS A:361 A:359 22.0 0.11 E -142.4 157.6 3.0 0.015 0.095 B:P07200:0.095
LYS B:361 B:359 74.0 0.37 E -144.9 159.4 48.0 0.24 0.13 A:P07200:0.13
LYS C:361 C:359 31.0 0.155 E -140.1 159.4 NA NA NA
LYS D:361 D:359 84.0 0.42 E -141.8 151.6 NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 LYS A:110 A:110 46.0 0.23 -137.3 -128.9 46.0 0.23 0.0
LYS B:110 B:110 46.0 0.23 -137.3 -129.0 46.0 0.23 0.0
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 LYS A:110 A:110 29.0 0.145 -168.2 -141.6 28.0 0.14 0.005 B:P01137:0.005
LYS B:110 B:110 30.0 0.15 -168.5 -148.2 30.0 0.15 0.0
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 LYS A:110 A:110 NA NA NA NA NA 34.0 0.17 NA
LYS B:110 B:110 NA NA NA NA NA 34.0 0.17 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 LYS A:110 A:110 38.0 0.19 E -165.9 146.0 38.0 0.19 0.0 HOH
 3.999
 NZ
 O
LYS B:110 B:110 46.0 0.23 E -163.3 158.8 46.0 0.23 0.0 HOH
 5.690
 NZ
 O
LYS G:110 C:110 40.0 0.2 E -161.6 143.1 NA NA NA
LYS H:110 D:110 45.0 0.225 E -162.7 157.6 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 LYS A:110 C:110 57.0 0.285 E -143.6 174.7 57.0 0.285 0.0
LYS B:110 D:110 61.0 0.305 E -143.3 171.1 61.0 0.305 0.0
LYS C:110 A:110 59.0 0.295 E -144.3 174.4 NA NA NA
LYS D:110 B:110 65.0 0.325 E -147.0 172.8 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 LYS B:110 B:388 39.0 0.195 E -134.7 151.0 25.0 0.125 0.07 D:P01137:0.07
LYS D:110 D:388 79.0 0.395 E -138.5 153.2 79.0 0.395 0.0
LYS F:110 F:388 40.0 0.2 E -137.5 152.7 NA NA NA
LYS H:110 H:388 92.0 0.46 E -140.0 151.2 NA NA NA
5ty4 2 ? 81.44 6e-54 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 LYS B:96 B:410 123.0 0.615 E -121.6 141.8 123.0 0.615 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 LYS A:388 A:388 62.0 0.31 E -140.6 165.4