Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 41836977 | . | G | A | CCDS33031.1:NM_000660.4:c.1153Cgc>Tgc_NP_000651.3:p.385R>C | Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5ffo | 3 | P01137 | 99.17 | 0.0 |
X-RAY |
2017-01-25 | ARG | C:358 | C:356 | 80.0 | 0.356 | -93.8 | -68.9 | 80.0 | 0.356 | 0.0 | |||||||
ARG | D:358 | D:356 | 139.0 | 0.618 | -95.0 | -69.5 | 139.0 | 0.618 | 0.0 | ||||||||||||||
ARG | G:358 | G:356 | 81.0 | 0.36 | -92.3 | -68.5 | 81.0 | 0.36 | 0.0 | ||||||||||||||
ARG | H:358 | H:356 | 140.0 | 0.622 | -94.0 | -70.9 | 133.0 | 0.591 | 0.031 |
G:P01137:0.031 |
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5vqp | 1 | P01137 | 99.17 | 0.0 |
X-RAY |
2017-11-15 | ARG | A:358 | A:356 | 73.0 | 0.324 | E | -106.2 | -21.7 | 73.0 | 0.324 | 0.0 | ||||||
6uja | 3 | P07200 | 94.18 | 0.0 |
EM |
2020-02-05 | ARG | C:358 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
3rjr | 1 | P07200 | 93.63 | 0.0 |
X-RAY |
2011-06-15 | ARG | A:358 | A:356 | 72.0 | 0.32 | -102.9 | -49.0 | 72.0 | 0.32 | 0.0 | |||||||
ARG | B:358 | B:356 | 69.0 | 0.307 | -102.9 | -49.0 | 69.0 | 0.307 | 0.0 | ||||||||||||||
ARG | C:358 | C:356 | 70.0 | 0.311 | -103.0 | -48.9 | NA | NA | NA | ||||||||||||||
ARG | D:358 | D:356 | 71.0 | 0.316 | -103.0 | -48.9 | NA | NA | NA | ||||||||||||||
5vqf | 1 | P07200 | 93.63 | 0.0 |
X-RAY |
2017-11-15 | ARG | A:358 | A:356 | 63.0 | 0.28 | -100.5 | -31.7 | 63.0 | 0.28 | 0.0 | |||||||
ARG | B:358 | B:356 | 78.0 | 0.347 | -101.4 | -31.2 | 78.0 | 0.347 | 0.0 | ||||||||||||||
ARG | C:358 | C:356 | 68.0 | 0.302 | -99.2 | -31.0 | NA | NA | NA | ||||||||||||||
ARG | D:358 | D:356 | 68.0 | 0.302 | -99.0 | -31.8 | NA | NA | NA | ||||||||||||||
1kla | 1 | P01137 | 100.0 | 1e-80 |
NMR |
1996-08-17 | ARG | A:107 | A:107 | 148.0 | 0.658 | E | -120.1 | -17.7 | 148.0 | 0.658 | 0.0 | ||||||
ARG | B:107 | B:107 | 145.0 | 0.644 | E | -120.6 | -17.9 | 145.0 | 0.644 | 0.0 | |||||||||||||
1klc | 1 | P01137 | 100.0 | 1e-80 |
NMR |
1996-08-17 | ARG | A:107 | A:107 | 164.0 | 0.729 | E | -144.2 | 13.3 | 164.0 | 0.729 | 0.0 | ||||||
ARG | B:107 | B:107 | 163.0 | 0.724 | E | -144.6 | 14.7 | 163.0 | 0.724 | 0.0 | |||||||||||||
1kld | 1 | P01137 | 100.0 | 1e-80 |
NMR |
1996-08-17 | ARG | A:107 | A:107 | NA | NA | NA | NA | NA | 156.0 | 0.693 | NA | ||||||
ARG | B:107 | B:107 | NA | NA | NA | NA | NA | 158.0 | 0.702 | NA | |||||||||||||
3kfd | 1 | P01137 | 100.0 | 1e-80 |
X-RAY |
2010-03-02 | ARG | A:107 | A:107 | 78.0 | 0.347 | E | -90.9 | -49.2 | 78.0 | 0.347 | 0.0 |
HOH |
3.488 |
CZ |
O |
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ARG | B:107 | B:107 | 90.0 | 0.4 | E | -101.3 | -15.7 | 90.0 | 0.4 | 0.0 |
HOH |
8.873 |
N |
O |
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ARG | G:107 | C:107 | 75.0 | 0.333 | E | -92.6 | -52.9 | NA | NA | NA | |||||||||||||
ARG | H:107 | D:107 | 92.0 | 0.409 | E | -108.6 | -18.4 | NA | NA | NA | |||||||||||||
4kv5 | 1 | P01137 | 100.0 | 1e-80 |
X-RAY |
2014-09-24 | ARG | A:107 | C:107 | 84.0 | 0.373 | E | -103.2 | -20.6 | 84.0 | 0.373 | 0.0 | ||||||
ARG | B:107 | D:107 | 73.0 | 0.324 | -104.2 | -20.2 | 73.0 | 0.324 | 0.0 | ||||||||||||||
ARG | C:107 | A:107 | 73.0 | 0.324 | E | -102.1 | -21.4 | NA | NA | NA | |||||||||||||
ARG | D:107 | B:107 | 82.0 | 0.364 | -101.2 | -21.4 | NA | NA | NA | ||||||||||||||
6gff | 2 | P01137 | 100.0 | 1e-80 |
X-RAY |
2018-11-07 | ARG | B:107 | B:385 | 73.0 | 0.324 | E | -103.8 | -34.6 | 73.0 | 0.324 | 0.0 | ||||||
ARG | D:107 | D:385 | 155.0 | 0.689 | E | -105.4 | -30.0 | 155.0 | 0.689 | 0.0 | |||||||||||||
ARG | F:107 | F:385 | 71.0 | 0.316 | E | -105.1 | -32.5 | NA | NA | NA | |||||||||||||
ARG | H:107 | H:385 | 109.0 | 0.484 | E | -104.6 | -32.3 | NA | NA | NA | |||||||||||||
5ty4 | 2 | ? | 81.44 | 6e-54 |
ELECTRON CRYSTALLOGRAPHY |
2017-04-26 | LYS | B:93 | B:407 | 73.0 | 0.365 | -131.5 | -85.1 | 73.0 | 0.365 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p01137-f1 | 1 | P01137 | 99.74 | 0.0 | ARG | A:385 | A:385 | 69.0 | 0.307 | -94.3 | -45.1 |