Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41837072 . G A CCDS33031.1:NM_000660.4:c.1058gCg>gTg_NP_000651.3:p.353A>V Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 ALA C:326 C:324 63.0 0.548 S -142.6 106.9 63.0 0.548 0.0
ALA D:326 D:324 67.0 0.583 S -145.8 95.3 67.0 0.583 0.0
ALA G:326 G:324 126.0 1.0 360.0 104.4 125.0 1.0 0.0 H:P01137:0.009
ALA H:326 H:324 67.0 0.583 S -142.9 94.3 67.0 0.583 0.0
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 ALA A:326 A:324 63.0 0.548 S -155.3 91.2 61.0 0.53 0.018 A:P01137:0.017
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 ALA C:326 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 ALA A:326 A:324 56.0 0.487 S -148.0 100.1 56.0 0.487 0.0
ALA B:326 B:324 69.0 0.6 S -129.9 80.3 64.0 0.557 0.043 A:P07200:0.043
ALA C:326 C:324 52.0 0.452 S -169.4 112.1 NA NA NA
ALA D:326 D:324 68.0 0.591 S -111.7 88.7 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 ALA A:326 A:324 57.0 0.496 S -133.2 111.7 57.0 0.496 0.0
ALA B:326 B:324 71.0 0.617 S -134.8 104.6 70.0 0.609 0.008 A:P07200:0.009
ALA C:326 C:324 59.0 0.513 S -134.4 112.2 NA NA NA
ALA D:326 D:324 61.0 0.53 S -136.4 102.6 NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 ALA A:75 A:75 28.0 0.243 -52.0 -177.1 19.0 0.165 0.078 B:P01137:0.078
ALA B:75 B:75 29.0 0.252 -51.6 -177.5 20.0 0.174 0.078 A:P01137:0.078
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 ALA A:75 A:75 20.0 0.174 -52.6 -175.1 10.0 0.087 0.087 B:P01137:0.087
ALA B:75 B:75 21.0 0.183 -52.7 -175.2 12.0 0.104 0.079 A:P01137:0.078
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 ALA A:75 A:75 NA NA NA NA NA 13.0 0.113 NA
ALA B:75 B:75 NA NA NA NA NA 14.0 0.122 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 ALA A:75 A:75 48.0 0.417 -161.0 169.9 47.0 0.409 0.008 B:P01137:0.009
 HOH
 3.857
 CB
 O
ALA B:75 B:75 40.0 0.348 -157.5 156.1 40.0 0.348 0.0 HOH
 4.597
 O
 O
ALA G:75 C:75 47.0 0.409 -153.9 169.7 NA NA NA
ALA H:75 D:75 40.0 0.348 -158.0 153.9 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 ALA A:75 C:75 43.0 0.374 -163.0 148.7 34.0 0.296 0.078 B:P01137:0.078
ALA B:75 D:75 45.0 0.391 -163.7 145.6 41.0 0.357 0.034 A:P01137:0.035
ALA C:75 A:75 38.0 0.33 S -166.7 146.5 NA NA NA
ALA D:75 B:75 51.0 0.443 -159.4 144.4 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 ALA B:75 B:353 61.0 0.53 S -139.6 119.0 51.0 0.443 0.087 I:Q14392:0.087
ALA D:75 D:353 72.0 0.626 S -138.5 85.0 55.0 0.478 0.148 C:P01137:0.026
I:Q14392:0.122
ALA F:75 F:353 57.0 0.496 S -141.6 140.3 NA NA NA
ALA H:75 H:353 71.0 0.617 S -140.4 105.8 NA NA NA
5ty4 2 ? 81.44 6e-54 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 SER B:61 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 ALA A:353 A:353 45.0 0.391 -139.7 146.1