Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41838128 . C A CCDS33031.1:NM_000660.4:c.919Ggc>Tgc_NP_000651.3:p.307G>C Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 GLY C:280 C:278 51.0 0.68 73.5 42.5 51.0 0.68 0.0
GLY D:280 D:278 49.0 0.653 71.8 38.5 49.0 0.653 0.0
GLY G:280 G:278 52.0 0.693 74.1 41.0 52.0 0.693 0.0
GLY H:280 H:278 48.0 0.64 70.8 39.4 48.0 0.64 0.0
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 GLY A:280 A:278 49.0 0.653 70.3 10.1 49.0 0.653 0.0
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 GLY C:280 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 GLY A:280 A:278 55.0 0.733 67.3 29.6 55.0 0.733 0.0
GLY B:280 B:278 56.0 0.747 67.4 29.6 56.0 0.747 0.0
GLY C:280 C:278 55.0 0.733 67.3 29.7 NA NA NA
GLY D:280 D:278 56.0 0.747 67.3 29.7 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 GLY A:280 A:278 62.0 0.827 69.0 25.8 62.0 0.827 0.0
GLY B:280 B:278 57.0 0.76 69.3 26.8 57.0 0.76 0.0
GLY C:280 C:278 56.0 0.747 69.5 25.4 NA NA NA
GLY D:280 D:278 58.0 0.773 69.4 26.9 NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 GLY A:29 A:29 26.0 0.347 60.7 16.8 20.0 0.267 0.08 B:P01137:0.08
GLY B:29 B:29 25.0 0.333 62.2 13.6 20.0 0.267 0.066 A:P01137:0.067
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 GLY A:29 A:29 28.0 0.373 63.7 11.7 24.0 0.32 0.053 B:P01137:0.053
GLY B:29 B:29 28.0 0.373 63.7 11.7 24.0 0.32 0.053 A:P01137:0.053
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 GLY A:29 A:29 NA NA NA NA NA 26.0 0.347 NA
GLY B:29 B:29 NA NA NA NA NA 28.0 0.373 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 GLY A:29 A:29 38.0 0.507 89.8 -13.5 23.0 0.307 0.2 B:P01137:0.2
 HOH
 3.849
 CA
 O
GLY B:29 B:29 50.0 0.667 84.0 21.8 38.0 0.507 0.16 A:P01137:0.16
 HOH
 8.694
 O
 O
GLY G:29 C:29 40.0 0.533 91.3 -2.1 NA NA NA
GLY H:29 D:29 51.0 0.68 80.7 22.9 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 GLY A:29 C:29 41.0 0.547 75.6 27.9 33.0 0.44 0.107 B:P01137:0.107
GLY B:29 D:29 41.0 0.547 71.1 26.1 37.0 0.493 0.054 A:P01137:0.053
GLY C:29 A:29 44.0 0.587 69.4 27.9 NA NA NA
GLY D:29 B:29 45.0 0.6 73.7 28.1 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 GLY B:29 B:307 63.0 0.84 69.1 28.0 61.0 0.813 0.027 D:P01137:0.027
GLY D:29 D:307 58.0 0.773 67.9 27.2 58.0 0.773 0.0
GLY F:29 F:307 62.0 0.827 69.3 28.2 NA NA NA
GLY H:29 H:307 56.0 0.747 68.7 27.8 NA NA NA
5ty4 2 ? 81.44 6e-54 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 GLY B:15 B:329 40.0 0.533 86.4 21.4 40.0 0.533 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 GLY A:307 A:307 42.0 0.56 65.5 19.5