Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41838150 . G A CCDS33031.1:NM_000660.4:c.897taC>taT_NP_000651.3:p.299Y>Y Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 TYR C:272 C:270 103.0 0.448 E -95.6 122.0 103.0 0.448 0.0
TYR D:272 D:270 114.0 0.496 -97.5 123.1 114.0 0.496 0.0
TYR G:272 G:270 101.0 0.439 E -96.2 122.6 101.0 0.439 0.0
TYR H:272 H:270 115.0 0.5 -100.4 126.0 115.0 0.5 0.0
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 TYR A:272 A:270 105.0 0.457 E -73.5 125.0 105.0 0.457 0.0
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 TYR C:272 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 TYR A:272 A:270 100.0 0.435 E -95.5 131.9 100.0 0.435 0.0
TYR B:272 B:270 104.0 0.452 E -95.5 132.0 104.0 0.452 0.0
TYR C:272 C:270 101.0 0.439 E -95.5 132.0 NA NA NA
TYR D:272 D:270 103.0 0.448 E -95.7 131.8 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 TYR A:272 A:270 102.0 0.443 E -87.7 135.5 102.0 0.443 0.0
TYR B:272 B:270 105.0 0.457 E -88.5 135.3 105.0 0.457 0.0
TYR C:272 C:270 97.0 0.422 E -87.4 135.9 NA NA NA
TYR D:272 D:270 101.0 0.439 E -87.1 136.0 NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 TYR A:21 A:21 100.0 0.435 -48.5 132.6 97.0 0.422 0.013 B:P01137:0.013
TYR B:21 B:21 97.0 0.422 -48.3 132.7 94.0 0.409 0.013 A:P01137:0.013
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 TYR A:21 A:21 101.0 0.439 E -48.4 133.5 97.0 0.422 0.017 B:P01137:0.017
TYR B:21 B:21 100.0 0.435 E -48.4 133.5 96.0 0.417 0.018 A:P01137:0.017
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 TYR A:21 A:21 NA NA NA NA NA 101.0 0.439 NA
TYR B:21 B:21 NA NA NA NA NA 104.0 0.452 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 TYR A:21 A:21 106.0 0.461 E -79.1 152.4 104.0 0.452 0.009 B:P01137:0.009
 HOH
 3.922
 CD2
 O
TYR B:21 B:21 108.0 0.47 E -109.1 134.1 106.0 0.461 0.009 A:P01137:0.009
 HOH
 5.261
 CD2
 O
TYR G:21 C:21 108.0 0.47 E -81.7 151.1 NA NA NA
TYR H:21 D:21 99.0 0.43 E -112.2 138.9 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 TYR A:21 C:21 100.0 0.435 E -107.0 139.0 98.0 0.426 0.009 B:P01137:0.009
TYR B:21 D:21 98.0 0.426 -108.8 134.9 96.0 0.417 0.009 A:P01137:0.009
TYR C:21 A:21 99.0 0.43 E -109.8 134.9 NA NA NA
TYR D:21 B:21 109.0 0.474 -110.1 134.4 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 TYR B:21 B:299 97.0 0.422 E -100.7 132.6 97.0 0.422 0.0
TYR D:21 D:299 96.0 0.417 -100.0 134.3 96.0 0.417 0.0
TYR F:21 F:299 97.0 0.422 E -101.8 131.8 NA NA NA
TYR H:21 H:299 96.0 0.417 E -99.9 134.0 NA NA NA
5ty4 2 ? 81.44 6e-54 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 TYR B:7 B:321 134.0 0.583 -121.4 140.0 134.0 0.583 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 TYR A:299 A:299 102.0 0.443 E -83.0 134.6