Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41838160 . C A CCDS33031.1:NM_000660.4:c.887cGg>cTg_NP_000651.3:p.296R>L Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 ARG C:269 C:267 62.0 0.276 E -93.9 150.4 61.0 0.271 0.005 D:P01137:0.004
ARG D:269 D:267 88.0 0.391 E -98.2 149.0 85.0 0.378 0.013 C:P01137:0.013
ARG G:269 G:267 60.0 0.267 E -93.6 151.1 59.0 0.262 0.005 H:P01137:0.004
ARG H:269 H:267 104.0 0.462 E -99.2 153.5 78.0 0.347 0.115 G:P01137:0.116
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 ARG A:269 A:267 131.0 0.582 E -95.4 120.2 73.0 0.324 0.258 A:P01137:0.258
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 ARG C:269 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 ARG A:269 A:267 50.0 0.222 E -89.2 142.6 37.0 0.164 0.058 B:P07200:0.058
ARG B:269 B:267 50.0 0.222 E -89.3 142.6 45.0 0.2 0.022 A:P07200:0.022
ARG C:269 C:267 50.0 0.222 E -89.3 142.7 NA NA NA
ARG D:269 D:267 50.0 0.222 E -89.2 142.6 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 ARG A:269 A:267 55.0 0.244 E -122.8 136.8 47.0 0.209 0.035 B:P07200:0.036
ARG B:269 B:267 50.0 0.222 E -122.7 138.9 43.0 0.191 0.031 A:P07200:0.031
ARG C:269 C:267 50.0 0.222 E -120.6 136.4 NA NA NA
ARG D:269 D:267 45.0 0.2 E -123.5 142.2 NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 ARG A:18 A:18 136.0 0.604 E -108.1 172.2 136.0 0.604 0.0
ARG B:18 B:18 137.0 0.609 E -107.7 173.3 137.0 0.609 0.0
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 ARG A:18 A:18 93.0 0.413 E -111.7 163.4 93.0 0.413 0.0
ARG B:18 B:18 90.0 0.4 E -112.5 162.9 90.0 0.4 0.0
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 ARG A:18 A:18 NA NA NA NA NA 80.0 0.356 NA
ARG B:18 B:18 NA NA NA NA NA 81.0 0.36 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 ARG A:18 A:18 67.0 0.298 E -107.4 168.6 67.0 0.298 0.0 HOH
 3.714
 CB
 O
ARG B:18 B:18 58.0 0.258 E -80.4 179.8 58.0 0.258 0.0 HOH
 5.453
 CB
 O
ARG G:18 C:18 67.0 0.298 E -98.9 174.2 NA NA NA
ARG H:18 D:18 58.0 0.258 E -80.5 -179.3 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 ARG A:18 C:18 58.0 0.258 E -117.6 146.0 58.0 0.258 0.0
ARG B:18 D:18 55.0 0.244 E -118.0 139.4 55.0 0.244 0.0
ARG C:18 A:18 53.0 0.236 E -118.3 140.4 NA NA NA
ARG D:18 B:18 54.0 0.24 E -117.5 143.9 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 ARG B:18 B:296 61.0 0.271 E -103.4 143.2 34.0 0.151 0.12 C:P01137:0.12
ARG D:18 D:296 34.0 0.151 E -102.2 139.6 12.0 0.053 0.098 A:P01137:0.093
I:Q14392:0.004
ARG F:18 F:296 62.0 0.276 E -104.9 142.0 NA NA NA
ARG H:18 H:296 39.0 0.173 E -100.5 140.1 NA NA NA
5ty4 2 ? 81.44 6e-54 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 ARG B:4 B:318 24.0 0.107 -156.9 151.9 24.0 0.107 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 ARG A:296 A:296 50.0 0.222 E -110.9 135.1