Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 41847807 . C A CCDS33031.1:NM_000660.4:c.841Gac>Tac_NP_000651.3:p.281D>Y Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5ffo 3 P01137 99.17 0.0 X-RAY
 2017-01-25 ASP C:254 C:252 45.0 0.3 -103.0 -137.8 45.0 0.3 0.0
ASP D:254 NA:NA DO NA DO DO DO NA NA NA
ASP G:254 G:252 45.0 0.3 -103.6 -138.7 45.0 0.3 0.0
ASP H:254 NA:NA DO NA DO DO DO NA NA NA
5vqp 1 P01137 99.17 0.0 X-RAY
 2017-11-15 ASP A:254 A:252 138.0 0.92 -110.8 130.6 138.0 0.92 0.0
6uja 3 P07200 94.18 0.0 EM
 2020-02-05 ASP C:254 NA:NA DO NA DO DO DO NA NA NA
3rjr 1 P07200 93.63 0.0 X-RAY
 2011-06-15 ASP A:254 A:252 57.0 0.38 -91.0 -165.5 57.0 0.38 0.0
ASP B:254 B:252 54.0 0.36 -92.8 -162.2 54.0 0.36 0.0
ASP C:254 C:252 61.0 0.407 -93.5 -174.0 NA NA NA
ASP D:254 D:252 63.0 0.42 -90.8 -173.5 NA NA NA
5vqf 1 P07200 93.63 0.0 X-RAY
 2017-11-15 ASP A:254 A:252 63.0 0.42 E -84.9 -177.8 63.0 0.42 0.0
ASP B:254 NA:NA DO NA DO DO DO NA NA NA
ASP C:254 C:252 61.0 0.407 E -102.2 178.0 NA NA NA
ASP D:254 NA:NA DO NA DO DO DO NA NA NA
1kla 1 P01137 100.0 1e-80 NMR
 1996-08-17 ASP A:3 A:3 41.0 0.273 B -103.8 172.8 41.0 0.273 0.0
ASP B:3 B:3 40.0 0.267 B -104.2 173.2 40.0 0.267 0.0
1klc 1 P01137 100.0 1e-80 NMR
 1996-08-17 ASP A:3 A:3 41.0 0.273 S -120.2 -170.1 41.0 0.273 0.0
ASP B:3 B:3 42.0 0.28 S -120.8 -169.8 42.0 0.28 0.0
1kld 1 P01137 100.0 1e-80 NMR
 1996-08-17 ASP A:3 A:3 NA NA NA NA NA 36.0 0.24 NA
ASP B:3 B:3 NA NA NA NA NA 36.0 0.24 NA
3kfd 1 P01137 100.0 1e-80 X-RAY
 2010-03-02 ASP A:3 A:3 36.0 0.24 B -103.4 178.4 22.0 0.147 0.093 F:P36897:0.093
 HOH
 4.667
 OD2
 O
ASP B:3 B:3 56.0 0.373 B -132.4 174.6 29.0 0.193 0.18 E:P36897:0.18
ASP G:3 C:3 37.0 0.247 B -103.0 179.9 NA NA NA
ASP H:3 D:3 56.0 0.373 E -140.1 171.1 NA NA NA
4kv5 1 P01137 100.0 1e-80 X-RAY
 2014-09-24 ASP A:3 C:3 42.0 0.28 B -98.1 -179.9 42.0 0.28 0.0
ASP B:3 D:3 41.0 0.273 B -99.0 -177.1 41.0 0.273 0.0
ASP C:3 A:3 42.0 0.28 B -99.2 -178.7 NA NA NA
ASP D:3 B:3 39.0 0.26 B -98.9 -177.0 NA NA NA
6gff 2 P01137 100.0 1e-80 X-RAY
 2018-11-07 ASP B:3 B:281 61.0 0.407 E -90.0 175.4 61.0 0.407 0.0
ASP D:3 D:281 90.0 0.6 -76.5 123.3 12.0 0.08 0.52 L:None:0.52
ASP F:3 F:281 60.0 0.4 E -97.0 -175.8 NA NA NA
ASP H:3 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01137-f1 1 P01137 99.74 0.0 ASP A:281 A:281 85.0 0.567 -47.2 79.7