Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 42473589 . A C CCDS12594.1:NM_152296.4:c.2686Tgg>Ggg_NP_689509.1:p.896W>G Homo sapiens ATPase Na+/K+ transporting subunit alpha 3 (ATP1A3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wgu 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 TRP A:899 A:899 31.0 0.122 E -106.0 138.9 0.0 0.0 0.122 B:P05027:0.122
TRP D:899 C:899 27.0 0.106 E -110.9 140.7 NA NA NA
3wgv 1 I7HD36 88.01 0.0 X-RAY
 2013-10-09 TRP A:899 A:899 30.0 0.118 E -100.7 139.1 0.0 0.0 0.118 B:P05027:0.118
TRP D:899 C:899 27.0 0.106 E -112.3 145.9 NA NA NA
4xe5 1 Q08DA1 87.61 0.0 X-RAY
 2016-03-09 TRP A:904 A:904 34.0 0.133 -111.2 129.3 2.0 0.008 0.125 B:G3MWR4:0.125
4hqj 1 P05024 87.51 0.0 X-RAY
 2013-10-02 TRP A:904 A:899 33.0 0.129 E -104.3 143.0 0.0 0.0 0.129 B:P05027:0.129
TRP D:904 C:899 31.0 0.122 E -104.7 142.7 NA NA NA
4hyt 1 P05024 87.51 0.0 X-RAY
 2013-06-26 TRP A:904 A:899 32.0 0.125 -101.2 141.3 1.0 0.004 0.121 B:P05027:0.122
TRP D:904 C:899 35.0 0.137 -100.9 141.5 NA NA NA
4res 1 P05024 87.51 0.0 X-RAY
 2015-01-28 TRP A:904 A:899 36.0 0.141 -128.5 135.8 1.0 0.004 0.137 B:P05027:0.137
TRP D:904 C:899 35.0 0.137 -126.9 136.3 NA NA NA
4ret 1 P05024 87.51 0.0 X-RAY
 2015-01-28 TRP A:904 A:899 36.0 0.141 -102.0 141.9 1.0 0.004 0.137 B:P05027:0.137
TRP D:904 C:899 35.0 0.137 -102.0 142.0 NA NA NA
7evx 1 P05024 87.51 0.0 X-RAY
 2021-07-07 TRP A:904 A:899 36.0 0.141 E -107.3 134.2 0.0 0.0 0.141 B:P05027:0.141
TRP D:904 C:899 35.0 0.137 E -107.9 134.1 NA NA NA
7d91 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 40.0 0.157 E -110.9 136.8 0.0 0.0 0.157 B:P05027:0.157
7d92 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 40.0 0.157 E -112.7 138.3 0.0 0.0 0.157 B:P05027:0.157
7d93 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 34.0 0.133 E -106.5 132.9 2.0 0.008 0.125 B:P05027:0.125
TRP C:899 C:899 33.0 0.129 E -105.5 134.1 NA NA NA
7d94 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 36.0 0.141 E -105.7 133.3 1.0 0.004 0.137 B:P05027:0.137
TRP D:899 C:899 33.0 0.129 E -103.9 134.6 NA NA NA
7ddf 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 33.0 0.129 E -112.7 127.8 0.0 0.0 0.129 B:P05027:0.129
TRP D:899 C:899 31.0 0.122 E -113.1 129.1 NA NA NA
7ddh 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 37.0 0.145 E -101.3 139.7 0.0 0.0 0.145 B:P05027:0.145
TRP D:899 C:899 36.0 0.141 E -100.3 139.9 NA NA NA
7ddi 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 33.0 0.129 E -101.4 129.3 0.0 0.0 0.129 B:P05027:0.129
TRP D:899 C:899 36.0 0.141 E -102.7 131.2 NA NA NA
7ddj 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 34.0 0.133 E -105.8 133.4 1.0 0.004 0.129 B:P05027:0.129
TRP D:899 C:899 32.0 0.125 E -104.6 134.6 NA NA NA
7ddk 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 35.0 0.137 E -107.2 131.5 0.0 0.0 0.137 B:P05027:0.137
TRP D:899 C:899 33.0 0.129 E -107.3 132.7 NA NA NA
7ddl 1 P05024 87.51 0.0 X-RAY
 2021-01-27 TRP A:899 A:899 33.0 0.129 E -104.7 133.8 0.0 0.0 0.129 B:P05027:0.129
TRP D:899 C:899 34.0 0.133 E -104.5 135.8 NA NA NA
3b8e 1 P05024 87.58 0.0 X-RAY
 2007-12-18 TRP A:881 A:899 90.0 0.353 H -108.0 60.7 31.0 0.122 0.231 B:P05027:0.231
TRP D:881 C:899 128.0 0.502 B -111.6 15.8 NA NA NA
3kdp 1 P05024 87.58 0.0 X-RAY
 2010-02-16 TRP A:881 A:899 31.0 0.122 E -102.4 144.3 2.0 0.008 0.114 B:P05027:0.114
TRP D:881 C:899 33.0 0.129 E -101.3 143.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 TRP A:875 A:899 43.0 0.169 E -112.9 138.8 0.0 0.0 0.169 B:P05027:0.169
TRP D:875 C:899 42.0 0.165 E -113.3 138.2 NA NA NA
2zxe 1 Q4H132 85.56 0.0 X-RAY
 2009-05-19 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:None:0.137
3a3y 1 Q4H132 85.56 0.0 X-RAY
 2009-09-08 TRP A:911 A:906 34.0 0.133 E -123.0 132.7 0.0 0.0 0.133 B:None:0.133
 HOH
 7.718
 CH2
 O
5avq 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5avr 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5avs 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.3 138.8 1.0 0.004 0.133 B:C4IX13:0.133
5avt 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5avu 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.9 0.0 0.0 0.137 B:C4IX13:0.137
5avv 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.1 138.9 0.0 0.0 0.137 B:C4IX13:0.137
5avw 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.3 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5avx 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.9 1.0 0.004 0.133 B:C4IX13:0.133
5avy 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 1.0 0.004 0.133 B:C4IX13:0.133
5avz 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.7 1.0 0.004 0.133 B:C4IX13:0.133
5aw0 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw1 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.3 138.8 1.0 0.004 0.133 B:C4IX13:0.133
5aw2 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw3 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 1.0 0.004 0.133 B:C4IX13:0.133
5aw4 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw5 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw6 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.1 138.9 0.0 0.0 0.137 B:C4IX13:0.137
5aw7 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.2 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw8 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 35.0 0.137 E -114.3 138.8 0.0 0.0 0.137 B:C4IX13:0.137
5aw9 1 Q4H132 85.56 0.0 X-RAY
 2015-09-02 TRP A:911 A:906 33.0 0.129 E -114.7 138.8 0.0 0.0 0.129 B:C4IX13:0.129

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13637-f1 1 P13637 100.0 0.0 TRP A:896 A:896 39.0 0.153 E -113.7 130.5
af-p50993-f1 1 P50993 88.81 0.0 TRP A:903 A:903 39.0 0.153 E -114.5 127.7
af-p05023-f1 1 P05023 88.03 0.0 TRP A:906 A:906 41.0 0.161 E -113.8 129.3